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临床试验/ACTRN12615001134516
ACTRN12615001134516撤回不适用

Dietary protein digestion and absorption kinetics and subsequent postprandial muscle protein accretion in healthy older people

Stijn Soenen0 个研究点目标入组 20 人开始时间: 2015年10月27日最近更新:

试验速览

阶段
不适用
状态
撤回
发起方
Stijn Soenen
入组人数
20

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional
分配方式
Randomised controlled trial
主要目的
Prevention
盲法
Blinded (masking used)

入排标准

年龄范围
65 Years 至 o limit(—)
性别
Male

入选标准

  • Body Mass Index (BMI): 22-30 kg/m2
  • Weight stable (<5% fluctuation in body weight in previous 3 months)

排除标准

  • smokers of cigarettes/cigars/marijuana;
  • intake of >2 standard drinks on >5 days per week;
  • intake of >4 cups of caffeinated drinks per day;
  • intake of any illicit substance;
  • vegetarians;
  • lactose intolerance;
  • Use of prescribed or non-prescribed medications (including vitamins and herbal supplements) which may effect gastrointestinal function or appetite - if subjects are willing, and able, to stop using medications, vitamins and/or supplements which affect gastrointestinal or energy metabolism during the study a washout period of at least 14 days prior to the first test day will apply;
  • food allergy(s), diabetes mellitus (fasting glucose >6.9 mmol/L), epilepsy, or gallbladder, pancreatic, cardiovascular or respiratory diseases;
  • significant gastrointestinal symptoms, disease or surgery (apart from uncomplicated appendectomy), as determined by a questionnaire;
  • impaired cognitive function (score <25 on Mini-Mental State Examination);
  • depression (a score >11 on the Geriatric Depression Questionnaire);
  • any other illness deemed significant by the investigator (including chronic illnesses not explicitly listed above);
  • low ferritin levels (<20ug/l) and plasma Hb levels (<130g/l), or blood donated in the 12 weeks prior to taking part in the study, in line with current Australian Red Cross Guidelines;
  • individuals who are found to be unable to comprehend the study protocol.

研究者

发起方
Stijn Soenen

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