Prevalence of H. Pylori Gastritis in Sleeve Gastrectomy Specimens

Completed

• Conditions: Gastritis H Pylori; Gastritis; Obesity Associated Disorder
• Interventions: Other: Giemsa stain

• Registration Number: NCT05101395
• Lead Sponsor: University of Jordan

Brief Summary

This is a cross-sectional study looking for prevalence of H.Pylori related gastritis among patients underwent sleeve gastrectomy over five year study period. The study also looks for possible association with patients's characteristics. Also, compares its findings with similar regional and international studies.

Detailed Description

Not available

Study Timeline

• Study Start: 2015-01-01
• Primary Completion: 2019-10-30
• Study Completion: 2019-10-30
• Status Verified: 2021-10
• Study First Submitted: 2021-10-19
• Study First Submitted QC: 2021-10-19
• Last Update Submitted: 2021-10-30
• Study First Posted: 2021-11-01
• Last Update Posted: 2021-11-08

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 810

Inclusion Criteria

• patients who underwent sleeve gastrectomy
• surgery was performed between January 2015 and October 2019

Exclusion Criteria

• patients whose resected specimens were not examined histopathologically

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Patients with Gastritis	Giemsa stain	Patients who underwent sleeve gastrectomy and the histopathology result of resected gastric specimen showed the presence of gastritis in it.

Primary Outcome Measures

Name	Time	Method
Prevalence of gastritis	start to end of the study, 5 years	proportion of patients who underwent sleeve gastrectomy who have gastritis in their resected gastric specimen at or during study period.; calculated as (number of pt with gastritis / number of examined resected gastric specimens)
Prevalence of H.pylori gastritis	start to end of the study, 5 years	proportion of patients who underwent sleeve gastrectomy who have H.pylori related gastritis in their resected gastric specimen at or during study period.; calculated as (number of pt with H.pylori gastritis / number of examined resected gastric specimens)

Secondary Outcome Measures

Name	Time	Method
likelihood ratio between H.pylori gastritis and BMI	start to end of the study, 5 years	The relationship between H.pylori gastritis and body mass index (BMI). weight and height will be combined to report BMI in kg/m\^2 likelihood ratio will be calculated by cross table analysis looking for using Statistical Analysis Software SPSS program version 26.
likelihood ratio between H.pylori gastritis and advancing age	start to end of the study, 5 years	The relationship between H.pylori gastritis and advancing age. likelihood ratio will be calculated by cross table analysis using Statistical Analysis Software SPSS program version 26.
Prevalence of other histopathological findings	start to end of the study, 5 years	proportion of patients who underwent sleeve gastrectomy who have histopathological findings not including gastritis or H.pylori related gastritis in their resected gastric specimen at or during study period.; calculated as (number of pt with the histopathological finding / number of examined resected gastric specimens)
likelihood ratio between H.pylori gastritis and female gender	start to end of the study, 5 years	The relationship between H.pylori gastritis and female gender. likelihood ratio will be calculated by cross table analysis using Statistical Analysis Software SPSS program version 26.

Trial Locations

Locations (1)

Jordan University Hospital; 🇯🇴 Amman, Jubaiha, Jordan