The effect of simvastatin on healing of extracted tooth socket

Phase 2

• Conditions: oss of teeth due to extractio.; Complete loss of teeth; K08.1

• Registration Number: IRCT20200324046848N1
• Lead Sponsor: Yazd University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 5 January 2021

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

The patient with not restorable tooth or crown, a root fracture, extensive decay Residual roots without apical lesions
Atraumatic tooth extraction
People who are in complete health status

Exclusion Criteria

Smokers
Pregnant and lactating women
History of radiation therapy and chemotherapy
Sensitivity to statin drugs

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The healing of hard tissue of extracted tooth socket. Timepoint: At baseline and 8 weeks after surgery. Method of measurement: Amount of bone trabecule formed in the extracted tooth socket is measured in histologic specimen using ImageJ software.

Secondary Outcome Measures

Name	Time	Method
Percentage of mineralized bone. Timepoint: 2 months after the surgery. Method of measurement: By histo-pathology evaluation.