Outcome After Laparoscopic Surgery for Peptic Ulcer Perforation

Completed

• Conditions: Intraabdominal Abscess After Procedure; Pneumonia; Operation Wound; Infection; Leakage
• Interventions: Procedure: Peritoneal irrigation; Procedure: Suction only

• Registration Number: NCT05147870
• Lead Sponsor: Chang Wei-Jung

Brief Summary

Despite advances in laparoscopic surgery for perforated peptic ulcer (PPU), intra-abdominal abscess (IAA) is recognized as one of the commonly reported complications with relation to the extent of infectious abdominal contamination. Herein, the investigators report their experience of laparoscopic surgery for PPU with/without peritoneal irrigation and discuss postoperative outcome. The investigators retrospectively examined the electronic medical records of the patients who underwent laparoscopic surgery for perforated peptic ulcer at a single medical center in Taiwan between January 2013 and August 2021. Retrospectively, the investigators would include those patients with clinical diagnosis of PPU who underwent emergent laparoscopic surgery. The patients with previous abdominal surgery, pathologic confirmed malignant ulcer perforation or concomitant ulcer bleeding were excluded. The investigators focused on post-operative complications and outcome after laparoscopic surgery with or without peritoneal irrigation. This information can be important in improving surgical options with respect to risk and potential benefits in this setting.

Detailed Description

Not available

Study Timeline

• Study Start: 2013-01-01
• Primary Completion: 2021-08-31
• Study Completion: 2021-08-31
• Status Verified: 2021-11
• Study First Submitted: 2021-11-05
• Study First Submitted QC: 2021-11-23
• Last Update Submitted: 2021-11-23
• Study First Posted: 2021-12-07
• Last Update Posted: 2021-12-07

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 150

Inclusion Criteria

• The patients with clinical diagnosis of PPU underwent laparoscopic repair surgery.

Exclusion Criteria

• The patients received surgery in an open approach or underwent laparoscopy initially but then intraoperatively converted to laparotomy.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Irrigation group	Peritoneal irrigation	-
Suction only group	Suction only	-

Primary Outcome Measures

Name	Time	Method
Short-term outcome with wound infection, pneumonia, leakage, and intraabdominal abscess	Through hospitalization, an average of 8 days	Complication grading used clavien dindo classification