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Clinical Trials/NCT01283451
NCT01283451
Completed
Not Applicable

Ability of Near Infrared Spectroscopy to Isolate Compartments of the Extremity

J&M Shuler1 site in 1 country63 target enrollmentJanuary 2010

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Acute Compartment Syndrome
Sponsor
J&M Shuler
Enrollment
63
Locations
1
Primary Endpoint
Near infrared spectroscopy
Status
Completed
Last Updated
7 years ago

Overview

Brief Summary

Near infrared spectroscopy (NIRS) provides a non-invasive means of continuously monitoring tissue oxygenation, which may be useful for diagnosis of acute compartment syndrome (ACS). Placement of these sensor pads on the surface of the skin must be such that light penetrates the intended compartment without inadvertently obtaining measurements of an adjacent compartment. The objective of this study is to examine whether the NIRS measurements of each compartment truly represent the tissue perfusion of the intended compartment, as indicated by the predictable decrease in muscle oxygenation of a given compartment in response to muscle fatigue. The investigators hypothesize that the tissue oxygenation values of the stimulated compartment will significantly decrease following muscle stimulation, indicating that the intended muscle compartment was successfully isolated. Additionally, the investigators hypothesize that NIRS values of unstimulated muscle compartments will not change from baseline.

Registry
clinicaltrials.gov
Start Date
January 2010
End Date
December 2016
Last Updated
7 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
J&M Shuler
Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • 18-75 years old
  • no current extremity injuries
  • willing to provide written informed consent

Exclusion Criteria

  • history of any anatomy-altering surgery to the extremity in question
  • history of peripheral vascular disease
  • history of pulmonary disease

Outcomes

Primary Outcomes

Near infrared spectroscopy

Time Frame: <30 minutes

NIRS values will be measured before and after muscle fatigue

Study Sites (1)

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