The effect of bevacizumab on success of trabeculectomy in glaucoma patients
Phase 2
- Conditions
- Primary open-angle glaucoma.Glaucoma (primary)(residual stage): capsular with pseudoexfoliation of lens, chronic simple, low-tension, pigmentary
- Registration Number
- IRCT2012120711647N1
- Lead Sponsor
- Vice chancellor for research, Tehran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 60
Inclusion Criteria
Inclusion Criteria: Primary open angle or pseudoexfoliative glaucoma patients 65 years or older who are candidates of standard trabeculectomy procedure (whose optic nerve function is failing or is likely to fail and is already on the maximum tolerated medical therapy and not likely to achieve a sufficient lOP reduction with laser treatment).
Exclusion criteria: Patients at high risk of failure of trabeculectomy, including aphakic, pseudophakic, uveitic, neovascular and juvenile glaucoma.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Success of trabeculectomy. Timepoint: six months after surgery. Method of measurement: Goldmann applanation tonometry (intraocular pressure between 6 and 21 ml Hg and 30% reduction of intraocular pressure compared to preoperative values).
- Secondary Outcome Measures
Name Time Method