Evaluate the effectiveness of ozone therapy on recuperation of patient suffering from Medication-related osteonecrosis of the jaw
Early Phase 1
Recruiting
- Conditions
- Osteonecrosis.Osteonecrosis due to drugsM87.1
- Registration Number
- IRCT20201201049555N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 28
Inclusion Criteria
Exposed bone or bone that can be probed through an intraoral or extraoral fistula that remains in the maxillofacial region for more than 8 weeks.
No history of radiotherapy
Possibility of frequent visits for ozone therapy sessions
Exclusion Criteria
Existence of pathological fractures while entering the study
Pregnant patients
Poor prognosis of cancer (with five-year SR less than 10%)
Incidence of pathological fractures in the jaw in the affected area
Perform radiotherapy during the treatment process
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Tenderness pain. Timepoint: After intervention. Method of measurement: Examination.
- Secondary Outcome Measures
Name Time Method