A Clinical Study of Laparoscopic Proximal Gastrectomy Based on PTST(Parachute-tunnel- Style Technique) Esophagogastric Anastomose.
Not Applicable
- Conditions
- Proximal GastrectomyGastroesophagostomyGastroesophageal-junction Cancer
- Registration Number
- NCT06217991
- Lead Sponsor
- Tang-Du Hospital
- Brief Summary
1. To evaluate the safety, simplicity and effectiveness of the gastric function (anti-reflux) preservation of the innovative "parachute-tunnel-style technique" (PTST) in laparoscopic proximal gastrectomy.
2. To investigate the correlation between anastomotic stenosis and blood supply of serosa-muscle flap,suture after esophagogastric anastomosis.(obtain objective indexes such as blood supply, healing pattern and length change of serosa-muscle flap through animal experiments)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ENROLLING_BY_INVITATION
- Sex
- All
- Target Recruitment
- 100
Inclusion Criteria
- Gastric cancer was confirmed histopathologically;
- Patients who may undergo proximal gastrectomy according to guidelines;
- Early upper gastric cancer, more than 1/2 of the distal gastric remnant remained after resection;
- Esophagogastric junction carcinoma with maximum diameter ≤4 cm;
- Patients with advanced upper gastric cancer (MSI-H) achieved cCR by neoadjuvant immunochemotherapy.
Exclusion Criteria
- Patients with systemic conditions that cannot tolerate laparoscopic surgery;
- Distal gastric remnant was less than 1/2 after proximal gastrectomy.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method occurrence rate of reflux esophagitis three month after surgery; six month after surgery * Visick score after surgery
* Los Angeles ratingoccurrence rate of anastomotic stenosis one month after surgery morbidity(%)
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
General Surgery Gastrointestinal Department,Tang-Du of Fourth Military Medical University
🇨🇳Xi'an, Shannxi Province, China
General Surgery Gastrointestinal Department,Tang-Du of Fourth Military Medical University🇨🇳Xi'an, Shannxi Province, China