The Protocol of Enhanced Recovery After Surgery in Colorectal Surgery
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Fudan University
- Enrollment
- 500
- Locations
- 1
- Primary Endpoint
- safety of the ERAS protocol and whether it can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery
Study Overview
Brief Summary
The purpose of this study is to determine whether ERAS is safe and can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery.
Detailed Description
The key factors that keep a patient in hospital after uncomplicated major colorectal surgery include the need for parenteral analgesia(persistent pain), intravenous fluids (persistent gut dysfunction), and bed rest (persistent lack of mobility). These factors often overlap and interact to delay return of function. Obviously, postoperative complications will also prolong the time until recovery and ultimately length of stay. A clinical pathway, called Enhanced Recovery After Surgery(ERAS), to accelerate recovery after colonic resection based on a multimodal programme with optimal pain relief, stress reduction with regional anaesthesia, early enteral nutrition and early mobilisation has demonstrated improvements in physical performance, pulmonary function, body composition and a marked reduction of length of stay.
Comparison(s): A total of 500 cases colorectal surgery were randomized to receive ERAS protocol or the traditional protocol, such as mechanical bowl preparation, intravenous fluids until bowl movement recovery and bed rest.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- None
Eligibility Criteria
- Ages
- 20 Years to 80 Years (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Colorectal surgery patients
- •Age 20～80
- •Without comorbidities which will influence prognosis, such as paralysis, spine cataface, or cardiac infarction
Exclusion Criteria
- •Emergency
- •Combined other organ resection
- •Age > 80
- •Comorbidities which will influence prognosis, such as paralysis, spine cataface, or cardiac infarction
Arms & Interventions
A
received enhanced recovery after surgery (ERAS) protocol in colorectal surgery
Intervention: enhanced recovery after surgery (ERAS) protocol (Procedure)
B
normal recovery protocol in colorectal surgery
Intervention: control (Procedure)
Outcomes
Primary Outcomes
safety of the ERAS protocol and whether it can decrease surgical stress, increase functional recovery and reduce complication rate in colorectal surgery
Time Frame: perioperation and until 30 days after surgery
Secondary Outcomes
No secondary outcomes reported