Inspiratory Muscle Strength as a Determinant of Functional Capacity Early After Coronary Artery Bypass Graft Surgery
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 2
- 主要终点
- Maximal inspiratory and expiratory pressure were measured (before, 7 and 30 days after surgery).
研究概览
简要总结
The purpose of this study is to evaluate the effects of a 6-day postoperative in hospital cardiopulmonary rehabilitation program on inspiratory muscle strength and its potential association with improved functional capacity after coronary artery bypass grafting surgery.
详细描述
Eligible patients were randomized to a cardiopulmonary rehabilitation program (Rehab; n = 10) or to usual care (Control; n = 10). The randomization was done by the Graphpad StatMate computerized program. Those patients assigned to Control were followed by their own physicians, received routine nursing assistance, were visited daily by the one of the investigators (CPM), but were not exposed to any specific respiratory or motor physical intervention. Those randomized to Rehab received the same medical and nursing care, but followed a structured physical therapy program twice a day.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
入排标准
- 年龄范围
- 21 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Previous history of more than one vessel coronary artery disease
- •Lifelong abstinence from tobacco
- •Formal indication for CABG
排除标准
- •Patients older than 75 years of age
- •Chronic renal failure (dialysis for more than 3 months)
- •Unstable angina in the 48 hours prior to CABG
- •Moderate or severe valve disease
- •Complex cardiac arrhythmia's
- •Inability to exercise the lower limbs
- •Previous pulmonary disease (forced vital capacity [FVC] < 80% of predicted and/or forced expiratory volume in 1 s [FEV1] < 70% of predicted)
- •Previous history of asthma.
结局指标
主要结局
Maximal inspiratory and expiratory pressure were measured (before, 7 and 30 days after surgery).
时间窗: From 1 day before surgery up to 30 days after surgery (CABG)
次要结局
- Six-minute walk test (6MWT) was performed 7 days after surgery, and maximal cardiopulmonary exercise testing (CPET) was performed 30 days after CABG.(From 7 days after surgery up to 30 days after surgery (CABG))