Efficacy of recombinant human fibroblast growth factor impregnated scaffold in the management of isolated maxillary gingival recession - A randomised controlled clinical trial
试验速览
- 阶段
- 4 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Changes in recession height
研究概览
简要总结
Recombinant human fibroblast growth factor (rhFGF) has shown promising results in the treatment of isolated maxillary gingival recession defects. When used in conjunction with a coronally advanced flap or biomaterials like collagen membranes, rhFGF enhances angiogenesis, promotes fibroblast proliferation, and accelerates periodontal tissue regeneration. Clinical outcomes demonstrate improved root coverage, increased keratinized tissue width, and superior soft tissue aesthetics, making rhFGF a valuable adjunct in regenerative periodontal therapy for localized recession. However there is no single study available on this in India. Hence this clinical trial.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant, Investigator and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 45.00 Year(s)（—）
- 性别
- All
入选标准
- •RT1 type recession Maxillary gingival recession Isolated gingival recession Thin soft tissue phenotype FMBS less than 20 FMPS less than 20.
排除标准
- •mokers Tobacco users Pregnancy Lactating mothers Not available for 24 months follow up Unwilling for periodic recall every 3 months.
结局指标
主要结局
Changes in recession height
时间窗: Baseline, 3 Months, 6 Months, 9 Months, 12 Months
Changes in recession width
时间窗: Baseline, 3 Months, 6 Months, 9 Months, 12 Months
Mean root coverage
时间窗: Baseline, 3 Months, 6 Months, 9 Months, 12 Months
Complete root coverage
时间窗: Baseline, 3 Months, 6 Months, 9 Months, 12 Months
Visual analog scale
时间窗: Baseline, 3 Months, 6 Months, 9 Months, 12 Months
Patient reported outcome measures
时间窗: Baseline, 3 Months, 6 Months, 9 Months, 12 Months
次要结局
- Patient satisfaction(Incidence of complications)
研究者
DrSaravanan SP
Army Dental Centre Research Referral Delhi