Anticoagulation with argatroban and prostacyclin compared to unfractionated heparin and prostacyclin during continous venovenous haemodialfiltation: a crossover trial
- Conditions
- Anticoagulation with argatroban and prostacyclin compared to unfractionated heparin and prostacyclin during continous venovenous haemodiafiltarion: a crossover trial
- Registration Number
- EUCTR2008-000042-31-AT
- Lead Sponsor
- niv. Klinik f. Anästhesie, Intensivmedizin und Schmerztherapie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- Not specified
Inclusion Criteria
a) aged over 18
b) requiring continous renal replacement therapy
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) yes
F.1.3.1 Number of subjects for this age range
Exclusion Criteria
a) severe liver dysfunction
b) suffering from heprin-induced thrombocytopenia
c) known hypersensitivity to argatroban or one of its ingredients
d) pregnant or nursing women
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: Comparison of duration of filter life during venovenous haemodiafiltration with anticoagulation with argatroban and prostacyclin or unfractionated heparin and prostacyclin;Secondary Objective: ;Primary end point(s): duration of filter life span during continous venovenous haemodiafiltration
- Secondary Outcome Measures
Name Time Method