MedPath

Vaccine Hesitancy in Black/African Americans With Rheumatic Diseases

Not Applicable
Active, not recruiting
Conditions
SLE
COVID-19 Vaccine
Rheumatic Diseases
COVID-19
Interventions
Behavioral: COVID-19 vaccine and booster training, and importance
Registration Number
NCT05822219
Lead Sponsor
Northwestern University
Brief Summary

To establish the efficacy of a community-based POL (Popular Opinion Leader) intervention with two different trainings designed to increase COVID-19 vaccine and booster uptake and reduce hesitancy among social networks of Black individuals with rheumatic conditions. The investigators will also determine the structure and composition of the personal and outreach social networks of POLs.

Detailed Description

Through community-academic partnerships in Boston and Chicago, investigators will recruit and randomly assign POLs who identify as Black with rheumatic conditions to two training arms in each city. Arms 1 and 2 will receive the same core curriculum addressing COVID-19 vaccine hesitancy, safety and efficacy. POLs will work in their communities to distributed information they learned in the trainings to members of their social network. The investigators will gather information about these social networks, assessing for differences in characteristics such as size, location, and who is in it (percentage of family, percentage Black, percentage with rheumatic conditions).

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
60
Inclusion Criteria

POLs:

18-85 years old; All genders; English-speaking; Self-identify as Black and/or African descent; Received ≥1 dose of a COVID-19 vaccine after 8.31.2022 (bivalent booster or updated COVID-19 vaccine [2023-2024] formula)

Social network members:

At least 18 years of age; All genders; English-speaking or Haitian Creole or Spanish-speaking if the POL also speaks Haitian Creole or Spanish; Not have received the updated COVID-19 vaccine 2023-2024 formula; Recent (within 3 months) COVID-19 infection and either undecided or no intention of receiving the vaccine.

Exclusion Criteria

Both POLs and social network members:

Under 18 years of age Pregnant women Institutionalized or incarcerated Those who are up to date on COVID vaccinations

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
COVID-19 vaccine and booster trainingCOVID-19 vaccine and booster training, and importanceGroup training involving COVID-19 vaccine and booster information, including background, development, and myths.
COVID-19 vaccine and booster training with extra undisclosed componentCOVID-19 vaccine and booster training, and importanceGroup training involving COVID-19 vaccine and booster information, including background, development, and myths. Contains extra training component that is undisclosed until the end of the study so as not to introduce bias.
Primary Outcome Measures
NameTimeMethod
Receipt of >1 COVID-19 vaccine or booster dose6 months

This will be measured as documentation of receipt of \>1 additional COVID-19 vaccine or booster dose above network members' baseline number of doses, scored yes or no.

Secondary Outcome Measures
NameTimeMethod
Structure and composition of the Popular Opinion Leader outreach networks.6 months

A mixed methods social network assessment tool will be used to compare the structures and compositions of the outreach social networks of the Popular Opinion Leaders between the two intervention arms. This is not scored but rather used to create social network map and to understand characteristics of social networks.

Change in COVID-19 vaccine hesitancy6 months

This will be measured as the network members' absolute change in vaccine hesitancy scale score comparing 6 months to baseline between the two study arms, using the validated 10-item Likert Vaccine Hesitancy Scale, score range 10-50.

Trial Locations

Locations (1)

Northwestern University

🇺🇸

Chicago, Illinois, United States

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