Breast Stimulation Versus Pitocin for Induction of Labor
Not Applicable
- Conditions
- Labor Induction
- Interventions
- Procedure: breast pump nipple stimulation
- Registration Number
- NCT00984347
- Lead Sponsor
- Hadassah Medical Organization
- Brief Summary
The purpose of the trial is to compare nipple stimulation with a breast pump to pitocin for induction of labor in term pregnancies.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 150
Inclusion Criteria
- 18 years and older
- completed 37 weeks gestation
- singleton pregnancy
- reassuring fetal heart rate at admission monitor
Exclusion Criteria
- multiple pregnancies
- known fetal malformations
- non reassuring NST
- polyhydramnios (AFI>220)
- oligohydramnios
- PET
- IUGR
- macrosomia (EFW >4000g)
- antepartum bleeding
- maternal fever
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description Breast Stimultion breast pump nipple stimulation nipple stimulation with a breast pump, calibrated at the lowest suction strength,operated alternately: 15 min one breast, 15 min second breast, 15 min rest, till appearance of regular uterine contractions (3 contractions in 10 min). the manipulation will continue for 3 hours of regular contractions. Oxytocin induction Oxytocin women in need for induction of labor due to medical indications, will receive continuous IV oxytocin
- Primary Outcome Measures
Name Time Method time from induction to delivery 24h
- Secondary Outcome Measures
Name Time Method fetal distress (monitor assessment, cord ph) 24 h cesarean section rate 24h
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms underlie oxytocin receptor activation during labor induction with breast pump stimulation?
How does breast pump nipple stimulation compare to synthetic oxytocin in terms of labor onset efficacy and maternal satisfaction?
Are there specific biomarkers that predict successful labor induction via mechanical nipple stimulation versus pharmacological oxytocin?
What are the potential adverse events associated with breast pump-induced labor compared to Pitocin administration?
What alternative labor induction methods are being studied alongside breast pump stimulation and oxytocin in term pregnancies?
Trial Locations
- Locations (1)
Hadassah University Hospital Mt. Scopus
🇮🇱Jerusalem, Israel
Hadassah University Hospital Mt. Scopus🇮🇱Jerusalem, IsraelYael Sciaky-Tamir, MDPrincipal Investigator