跳至主要内容
临床试验/CTRI/2021/08/036083
CTRI/2021/08/036083尚未招募不适用

A randomised controlled trial to assess the efficacy of Pericapsuler Nerve Group Block verses Lumbar Plexus Block for postoperative analgesia in patients undergoing hip surgery

Lady Hardinge Medical College1 个研究点 分布在 1 个国家目标入组 100 人开始时间: 2021年7月9日最近更新:
适应症

试验速览

阶段
不适用
状态
尚未招募
入组人数
100
试验地点
1
主要终点
Mean opioid consumption (in mg/kg) at the end of 24 hours postoperatively in both PENG block and lumbar plexus block group

研究概览

简要总结

Hip fracture is a common orthopedic emergency, & associated with significant morbidity and mortality. Surgical reduction and fixation is the definitive treatment in most patients to improve mobility and quality of life. Adequate pain relief is essential in the postoperative period to enable ambulation and initiation of physiotherapy.

Various methods have been used to provide post op analgesia. Intravenous patient-controlled analgesia (IV PCA) or epidural analgesia are the most common methods. IV PCA is associated with poor pain control and opioid associated complications. Epidural analgesia may lead to hemodynamic instability and bilateral motor block.

Recently, peripheral nerve blockade has emerged alternative analgesic approach.4 Femoral nerve block and fascia illiaca block are useful however they are associated with inadequate pain control for hip surgery because of low propensity to block obturator nerve.

Lumbar plexus block or psoas compartment blocks has been considered Gold standard, as it reliably block all its branches including obturator nerve and provide potent analgesia with reduce opioid consumption for hip surgery. It is a deep block and technically challenging even with the use of ultrasound.

Recently ultrasound guided Pericapsular Nerve Group (PENG) block has been described which block articular branches of hip supplied by femoral, obturator, and accessory obturator nerve. Technique for PENG block is easy as it is quite superficial as well as initial data on its application and hip surgery is in encouraging.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Investigator Blinded

入排标准

年龄范围
18.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • •Adult patients ASA I and ASA II 18-70 years posted for hip surgery.

排除标准

  • •1.Any known drug allergies.
  • •2.Contraindication to nerve block like coagulopathy, bleeding diathesis and local infection 3.Patient requires general anaesthesia during surgery.

结局指标

主要结局

Mean opioid consumption (in mg/kg) at the end of 24 hours postoperatively in both PENG block and lumbar plexus block group

时间窗: Mean opioid consumption (in mg/kg) at the end of 24 hours postoperatively in both PENG block and lumbar plexus block group

次要结局

  • 1.Mean NRS on rest at 0, 4, 8, 12&24 hr postoperatively in both the group(2.Mean NRS on limb movement at 0, 4, 8, 12&24 hr postoperatively in both the group)

研究者

申办方类型
Government medical college

研究点 (1)

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