Is it Possible to Replace Fentanyl by Non Narcotic Medication for Induction and Maintenance of Anesthesia in Minor Procedures?
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 120
- 试验地点
- 1
- 主要终点
- Intubation with less hemodynamic changes
研究概览
简要总结
To compare between fentanyl group and ketamine lidocaine group for induction of anesthesia as regards hemodynamics and smooth intubation.
详细描述
Two groups each with 60 patients Group I anesthesia initiated by propofol, fentanyl and cisatracurium. Group II anesthesia initiated by ketamine, lidocaine, propofol and cisatracurium.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •ASA I and II between
- •Age between 18-55 years
- •Undergoing minor surgical procedure less than an hour.
排除标准
- •Patients with hypertension
- •Patients with Ischemic heart diseases
- •Patients with chronic renal or liver diseases
研究组 & 干预措施
Ketamine and lidocaine
Administered propofol, ketamine and lidocaine for induction.
干预措施: Cisatracurium (Drug)
Fentanyl
Administered propofol and fentanyl for induction.
干预措施: Propofol (Drug)
Fentanyl
Administered propofol and fentanyl for induction.
干预措施: Fentanyl (Drug)
Fentanyl
Administered propofol and fentanyl for induction.
干预措施: Cisatracurium (Drug)
Ketamine and lidocaine
Administered propofol, ketamine and lidocaine for induction.
干预措施: Ketamine (Drug)
Ketamine and lidocaine
Administered propofol, ketamine and lidocaine for induction.
干预措施: Propofol (Drug)
Ketamine and lidocaine
Administered propofol, ketamine and lidocaine for induction.
干预措施: Lidocaine (Drug)
结局指标
主要结局
Intubation with less hemodynamic changes
时间窗: Anesthesia time
changes in pulse rate during anesthesia
Smooth Maintenance of anesthesia
时间窗: anesthesia time
changes in blood pressure during anesthesia
less postoperative pain killers
时间窗: 24 hours postoperative
amount of pain killers used and timing
次要结局
未报告次要终点
研究者
Ayman Anis Metry
Assistant professor
Ain Shams University