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临床试验/CTRI/2025/12/099744
CTRI/2025/12/099744尚未招募不适用

Influence of Pneumonia on the Physiological Cost Index (PCI) of Walking

Dr Sanjana B Hubballi1 个研究点 分布在 1 个国家目标入组 63 人开始时间: 2026年2月1日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
63
试验地点
1
主要终点
physiological cost index

研究概览

简要总结

Titled "Influence of Pneumonia on the Physiological Cost Index (PCI) of Walking" investigates how pneumonia impacts energy expenditure during ambulation. Pneumonia, a serious respiratory infection caused by bacteria, viruses, or fungi, leads to inflammation of the alveoli and compromises respiratory efficiency. It remains a major public health issue in India, particularly affecting the elderly and individuals with weakened immune systems. The condition often results in reduced exercise tolerance, fatigue, and impaired functional mobility. While conventional tools such as spirometry are effective for assessing lung function, their reliance on specialized equipment and trained personnel makes them less feasible in resource-limited settings. The Physiological Cost Index (PCI), a simple and non-invasive method, offers an alternative by estimating energy expenditure through heart rate changes in relation to walking speed. This cross-sectional study will recruit adults aged 40–70 years with clinically diagnosed pneumonia who are medically stable and able to walk independently. Participants will undergo a 6-minute walk test (6MWT) during which key physiological parameters heart rate, respiratory rate, oxygen saturation, and blood pressure, will be measured pre- and post-test. PCI will be calculated using MacGregor’s formula: (Post-walking Heart Rate – Resting Heart Rate) / Speed (m/min). Additional outcome measures include the Borg Scale for perceived exertion, CURB-65 pneumonia severity score, Fatigue Severity Scale (FSS), and other clinical markers. Individuals with unstable cardiovascular conditions, neuromuscular impairments, ongoing fever, or chronic respiratory disorders will be excluded. This study is distinctive in applying PCI to pneumonia patients—a population not commonly assessed for ambulatory energy cost. It aims to reveal elevated PCI values in this group, reflecting the increased physiological demand associated with pneumonia. The findings are expected to guide physiotherapists in developing tailored rehabilitation programs based on functional limitations. Moreover, it supports the integration of PCI into routine physiotherapy assessments as a cost-effective and accessible tool for tracking functional recovery in both hospital and community settings.

研究设计

研究类型
Observational

入排标准

年龄范围
40.00 Year(s) 至 70.00 Year(s)(—)
性别
All

入选标准

  • 1.Age 40-70 years.
  • 2.Confirmed diagnosis of pneumonia by clinical, radiological or microbiological confirmation.
  • Hemodynamically stable with no active shock or unstable vitals.
  • 4.Able to ambulate independently with or without assistive devices.
  • 5.Resting SpO2 greater than or equal to 88percent on room air or supplemental oxygen.
  • 6.Medically cleared for physical activity.

排除标准

  • 1.Unstable cardiovascular conditions 2.Uncontrolled hypertension, arrhythmias, recent myocardial infarction 3.Severe orthopedic or neuromuscular limitations that impair walking 4.Cognitive impairment that interferes With understanding instructions 5.Pregnancy 6.Use of beta-blockers or medications that significantly blunt heart rate response 7.Ongoing fever greater than or equal to 38.5°C at the time of testing (pneumonia group) 8.History of chronic respiratory disease (e.g., COPD, asthma) in control group 9.Inability or refusal to give informed consent.

结局指标

主要结局

physiological cost index

时间窗: outcome measures are taken after completion of the 6-minute walk test

次要结局

  • Borgs rate of perceived exertion(Scale is taken after completion of Minutes walk)

研究者

发起方
Dr Sanjana B Hubballi
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Sanjana B Hubballi

SDM College of physiotherapy

研究点 (1)

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