Comparison study of the effects between DPP-4 inhibitor and sulfonylurea on glucagon secretion in type 2 diabetic patients treated with biguanide
- Conditions
- Type 2 diabetes
- Registration Number
- JPRN-UMIN000012262
- Lead Sponsor
- Divison of Diabetes and Metabolism,Itabashi Hospital, Nihon University School of Medicine
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 40
Not provided
1)iabets mellitus due to glucagon-producing tumor 2) patients:the medicine is changed within the last three months 3) Type 1 diabtes,HbA1c: higher than 10.5%,patients who require hospitalization for high blood glucose or diabetic ketoasidosis 4) patients treated with Dpp-4 inhibitor, sulfonylurea or insulin injection 5)patients with nephrotic syndrome 6) hypersensitivity to drugs on this study 7) renal dysfunction (1.3 and 1.2 mg/dL or more for male and female, respectively) 8)hepatitis (AST,ALT: three folds higher than baseline), 9) pregnancy, possibly pregnant woman 10) patients who are inadequate to enter this study due to the other reasons by physician's judgments
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method