Effects of Supplementation with vitamin D on anti aging protein klotho
- Conditions
- vitamin d deficiency.Vitamin D deficiency, unspecified
- Registration Number
- IRCT201511152709N36
- Lead Sponsor
- International Campus of Iran University of medical science
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 90
more than 60 years old; old people with deficiency or insufficiency of serum Vitamin D levels (less than 30ng/ml serum 25-hydroxyvitamin D); Willingness to cooperate in the study; Lack of sensitivity to Vitamin D Supplement; no Consumption of multi vitamin, mineral and omega 3 Supplement; no Consumption of Vitamin D Supplement; Non-diabetic people; Without a history of stroke or Severe card
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Serum soluble klotho. Timepoint: before and after intervention. Method of measurement: ELISA.;25(OH)D. Timepoint: before and after intervention. Method of measurement: ELISA.;1,25(OH)2D. Timepoint: before and after intervention. Method of measurement: ELISA.;FBS. Timepoint: before and after intervention. Method of measurement: Colorimetric.;HgA1c. Timepoint: before and after intervention. Method of measurement: Ion exchange.;Hs-CRP. Timepoint: before and after intervention. Method of measurement: ELISA.;Super Oxide Dismutase assay. Timepoint: before and after intervention. Method of measurement: Calorimetry.;Cognitive function. Timepoint: before and after intervention. Method of measurement: questionnaire.
- Secondary Outcome Measures
Name Time Method Blood pressure. Timepoint: Before and after intervention. Method of measurement: Mercury sphygmomanometer.;Weight. Timepoint: before and after intervention. Method of measurement: Digital scale.;Dietary intake. Timepoint: before and after intervention. Method of measurement: questionare.;Body mass index. Timepoint: before and after intervention. Method of measurement: Calculation.;Physical activity. Timepoint: before and after intervention. Method of measurement: questionare.;Sun exposure. Timepoint: before and after intervention. Method of measurement: questionare.;Drug consumption. Timepoint: before and after intervention. Method of measurement: questionare.;Smoking. Timepoint: before and after intervention. Method of measurement: questionare.
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