ACTRN12621001671853尚未招募未知
Impact of hyperbaric oxygen in poor ovarian responders on assisted reproduction technology treatment pregnancy rate
José Miguel Raimundo0 个研究点目标入组 40 人开始时间: 2021年12月6日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 40
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Treatment
- 盲法
- Open (masking not used)
入排标准
- 年龄范围
- 19 Years 至 50 Years(—)
- 性别
- Female
入选标准
- •poor ovarian responders
- •Bologna Criteria”:
- •1) advanced women’s age (greater than 40 years) or any other risk factor for POR;
- •2) recovering a few numbers of oocytes (less than 3 oocytes) following previous ovarian stimulation;
- •3) abnormal ovarian reserve test (antral follicle counts 5–7 or anti-Mullerian hormone 0.5–1.1 ng/mL).
- •A poor responder is defined by the presence of two of these criteria.
排除标准
- •rFSH - recombinant follicle stimulating hormone
- •Prior hypersensitivity to recombinant FSH preparations or one of their excipients
- •High levels of FSH indicating primary gonadal failure
- •Uncontrolled thyroid or adrenal dysfunction
- •Sex hormone dependent tumors of the reproductive tract and accessory organs
- •An organic intracranial lesion such as a pituitary tumor
- •Abnormal uterine bleeding of undetermined origin (see Selection of Patients)
- •Ovarian cyst or enlargement of undetermined origin (see Selection of Patients)
- •Hyperbaric oxygen
- •Pleural diseases: History of pneumothorax, post-pleurodesis status, thoracotomy or chest trauma with subsequent significant restriction of pleural mobility
- •Lung diseases: Bullous emphysema
- •Uncontrolled claustrophobia
- •Drugs: bleomycin;cisplatin, doxorubicin and disulfiram
- •Uncontrolled heart disease
研究者
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