Human response to neck treatment following concussio

Not Applicable

Completed

• Conditions: Persistent post-concussion symptoms; Physical Medicine / Rehabilitation - Physiotherapy; Neurological - Other neurological disorders

• Registration Number: ACTRN12622000479707
• Lead Sponsor: Gerard Farrell

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2022-03-25
• Study Completion: 2023-04-08
• Last Update Posted: 22 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Male
• Target Recruitment: 19

Inclusion Criteria

Males with a diagnosis of persistent post-concussion symptoms aged between 19-35 years old who own an iPhone.

Exclusion Criteria

Participants will be excluded if they are:
-Asymptomatic.
-Unable to refrain from external treatment (treatment session in person or online) or change in treatment (progression or modification of existing treatment) for three consecutive days, specifically days five to seven (out of eight), so the intervention can be performed, and salivary samples collected (primary outcome).
-Confounding factors to the outcome measurements. These include; Serious medical or psychiatric disorder; co-morbid musculoskeletal or serious conditions which may confound treatment or anticipated recovery; NSAIDs use; recent steroid injections; currently have an endocrine, central nervous system, cardiovascular, or a mental health disorder; systemic glucocorticoid or cardioactive medication; serotonin-norepinephrine reuptake inhibitors; moderate to severe traumatic brain injury. Note, Participants prescribed with psychotropic medication for treatment of concussion-related symptoms (e.g., headache and migraine) will be permitted to be enrolled in the study provided they are not prescribed serotonin-norepinephrine reuptake inhibitors (e.g., desvenlafaxine, venlafaxine, duloxetine, etc.) given their impact on autonomic function.
-Contra-indications to the intervention. If any precautions to manual therapy are present, participants will be excluded on a case-by-case basis.

Study & Design

• Study Type: Interventional
• Study Design: Not specified