EVALUATION OF DYNAMIC MRI WITH T1-MAPS CORRELATED WITH HISTOPATHOLOGY IN PATIENTS WITH CROHN'S DISEASE.
Recruiting
- Conditions
- Crohn's disease, ziekte van Crohn
- Registration Number
- NL-OMON19958
- Lead Sponsor
- Academic Medical Center, department of radiology
- Brief Summary
/A
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 20
Inclusion Criteria
1. Proven Crohn's Disease (by endoscopy or histopathology);
2. Scheduled to undergo small-bowel surgery for Crohn's Disease.];
Exclusion Criteria
1. Age < 18 years;
2. General contraindications for MRI (pacemaker, claustrophobia, renal insufficiency and pregnancy).
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The main study parameter will be the accuracy of detecting disease activity and efficacy of DCE MRI at MR in patients with proven Crohn’s disease as compared to histopathology.
- Secondary Outcome Measures
Name Time Method The secondary study parameters will be the accuracy of detecting disease activity on DCE-MRI as compared to CDAI and CRP. Also the aspect of the bowel wall (serositis or normal) as seen during surgery will be compared to the MRI and the histology.