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VR and Script Training of PWA

Not Applicable
Active, not recruiting
Conditions
Aphasia, Acquired
Chronic Stroke
Interventions
Behavioral: VR-based script training
Behavioral: Conventional script training
Registration Number
NCT05667480
Lead Sponsor
The Hong Kong Polytechnic University
Brief Summary

The goal of this intervention study is to investigate the effects of immersive virtual reality in rehabilitation of language and communication of individuals with post-stroke aphasia. The main research questions are:

1. Is VR-based script training a feasible treatment to Cantonese-speaking PWA?

2. Will VR-based script training, when compared to conventional script training, better enhance treatment outcomes in functional communication of PWA?

Participants will be assessed before, in the middle of, immediately after treatment and 8-week post treatment in terms of their performance on:

1. Accuracy and time for producing trained scripts.

2. Accuracy and time for producing un-trained scripts

3. Standardized aphasia test on severity of language impairment

4. Standardized aphasia test on functional communication

The participants will be randomly allocated to receive one of the treatment:

1. Virtual reality-based computerized script training; or

2. Computerized script training without virtual reality Researchers will compare the treatment outcomes of the two treatment conditions and see if treatment with virtual reality would better promote outcomes when compared to training without virtual reality.

Detailed Description

Not available

Recruitment & Eligibility

Status
ACTIVE_NOT_RECRUITING
Sex
All
Target Recruitment
26
Inclusion Criteria
  1. a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
  2. premorbid fluent Cantonese speakers,
  3. aged between 30 and 80 years,
  4. no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
  5. no motor speech disorders of moderate to severe level, and
  6. normal or corrected-to-normal vision and hearing functions
Exclusion Criteria
  1. concurrent participation in other aphasia treatment trials, and
  2. incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
VR-based script trainingVR-based script training-
Conventional script trainingConventional script training-
Primary Outcome Measures
NameTimeMethod
Percentage correct in reading aloud the sentences included in the trained scriptsFrom baseline up to 1-week post training

Trained scripts will be shown in written form while the PWA will be asked to read aloud the scripts.

Time required in read aloud of trained scriptsFrom baseline up to 1-week post training

Total time to read aloud the trained scripts

Percentage correct in spontaneous production of the sentences included in the trained scriptsFrom baseline up to 1-week post training

No written cue will be provided while the PWA will produce the scripts upon questions.

Time required for spantaneous production of trained scriptsFrom baseline up to 1-week post training

No written cue will be provided while the PWA will produce the scripts upon questions.

Secondary Outcome Measures
NameTimeMethod
CABFrom baseline up to 1-week post training

Cantonese version of the Western Aphasia Battery

Percentage correct in producing untrained but related scriptsFrom baseline up to 1-week post training

No written cue will be provided while the PWA will produce the untrained scripts that share similar contexts with the trained scripts.

CANELTFrom baseline up to 1-week post training

Cantonese version of the Amsterdam-Nijmegen Everyday Language Test (ANELT; Blomert et al., 1994)

Trial Locations

Locations (1)

Hong Kong Polytechnic University

🇭🇰

Hong Kong, Hong Kong SAR, Hong Kong

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