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Clinical Trials/NCT05667480
NCT05667480
Active, not recruiting
Not Applicable

Utilization of Immersive Virtual Reality in Computerized Script Training for People with Aphasia: a Feasibility Study

The Hong Kong Polytechnic University1 site in 1 country26 target enrollmentApril 10, 2023

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Aphasia, Acquired
Sponsor
The Hong Kong Polytechnic University
Enrollment
26
Locations
1
Primary Endpoint
Percentage correct in reading aloud the sentences included in the trained scripts
Status
Active, not recruiting
Last Updated
last year

Overview

Brief Summary

The goal of this intervention study is to investigate the effects of immersive virtual reality in rehabilitation of language and communication of individuals with post-stroke aphasia. The main research questions are:

  1. Is VR-based script training a feasible treatment to Cantonese-speaking PWA?
  2. Will VR-based script training, when compared to conventional script training, better enhance treatment outcomes in functional communication of PWA?

Participants will be assessed before, in the middle of, immediately after treatment and 8-week post treatment in terms of their performance on:

  1. Accuracy and time for producing trained scripts.
  2. Accuracy and time for producing un-trained scripts
  3. Standardized aphasia test on severity of language impairment
  4. Standardized aphasia test on functional communication

The participants will be randomly allocated to receive one of the treatment:

  1. Virtual reality-based computerized script training; or
  2. Computerized script training without virtual reality Researchers will compare the treatment outcomes of the two treatment conditions and see if treatment with virtual reality would better promote outcomes when compared to training without virtual reality.
Registry
clinicaltrials.gov
Start Date
April 10, 2023
End Date
June 30, 2025
Last Updated
last year
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • a stroke onset more than six months, with an Aphasia Quotient (AQ) below 96.4, as evaluated by the Cantonese version of Western Aphasia Battery (CAB; Yiu, 1992),
  • premorbid fluent Cantonese speakers,
  • aged between 30 and 80 years,
  • no reported progressive neurogenic disorders such as dementia or Parkinson's disease,
  • no motor speech disorders of moderate to severe level, and
  • normal or corrected-to-normal vision and hearing functions

Exclusion Criteria

  • concurrent participation in other aphasia treatment trials, and
  • incompatibility with immersive VR exposure such as complains of nausea, headache, or other severe discomforts during trial use of a head-mounted device during screening.

Outcomes

Primary Outcomes

Percentage correct in reading aloud the sentences included in the trained scripts

Time Frame: From baseline up to 1-week post training

Trained scripts will be shown in written form while the PWA will be asked to read aloud the scripts.

Time required in read aloud of trained scripts

Time Frame: From baseline up to 1-week post training

Total time to read aloud the trained scripts

Percentage correct in spontaneous production of the sentences included in the trained scripts

Time Frame: From baseline up to 1-week post training

No written cue will be provided while the PWA will produce the scripts upon questions.

Time required for spantaneous production of trained scripts

Time Frame: From baseline up to 1-week post training

No written cue will be provided while the PWA will produce the scripts upon questions.

Secondary Outcomes

  • CAB(From baseline up to 1-week post training)
  • Percentage correct in producing untrained but related scripts(From baseline up to 1-week post training)
  • CANELT(From baseline up to 1-week post training)

Study Sites (1)

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