A human trial of Gastrodia elata Blume and Glycyrrhiza uralensis Fischer extracts mixture on improvement of Cognitive(memory) Functio

Not Applicable

Recruiting

Conditions: Symptoms, signs and abnormal clinical and laboratory findings, NEC

Registration Number: KCT0007338

Lead Sponsor: Wonkwang University, Gwangju Medical Center

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: All

Target Recruitment: 100

Inclusion Criteria

1) Those who complain of subjective memory loss {one or more points in the subjective memory loss questionnaire (SMCQ)}
2) Those who Korean-Mini Mental State Examination(K-MMSE) results in 18~28 scores
3) Participants who have fully understand the information provided about the study voluntarily decided to participate and agree to comply with precautions.

Exclusion Criteria

1)Patients with a clinically significant disease requiring treatment (i.e., acute or chronic cardiovascular system, endocrine system, immune system, respiratory system, kidney and urinary system, neuropsychiatric system, musculoskeletal inflammation, inflammatory disease, blood and tumor disease, gastrointestinal disease, etc.)
2)Patients with a history of antipsychotic medication use within 3 months prior to the screening examination
3)Patients with a history of clinically significant hypersensitivity reactions to drugs and test products
4)Patients who have participated in other clinical trials within 3 months prior to the screening examination
5)Patients with a Severe score of 29-63 points as a result of the Depression Scale (BDI) test
6)Patients who are judged ineligible to participate in the trial by the principal investigator for other reasons, including laboratory test outcomes

Study & Design

Study Type: Interventional Study

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Alzheimer's Disease Assessment Scale-cognitive subscale

Secondary Outcome Measures

Name	Time	Method
Korean Mini-Mental Status Examination;Subject Memory Complain Questionnaire;Perceived stress scale);Beck Depression Inventory;Brain-derived neurotrophic factor;amyloid ß