Prevention of atherosclerosis by SGLT2 inhibitor; multicenter, randomized controlled study - PROTECT

Department of Cardiovascular Medicine, Saga University0 个研究点目标入组 479 人开始时间: 2015年7月31日最近更新: 2023年10月17日

适应症

试验速览

暂无简介。

•1) Type 1 diabetes 2) Has history of severe ketosis, diabetic coma, or precoma within 6 months 3) Has severe infection, serious trauma, or pre or post surgery (including carotid endarterectomy and stent implantation) 4) With severe renal dysfunction (eGRF <45 mL/min/1.73m2 or patient undergoing artificial dialysis) 5) Has history of myocardial infarction, angina, percutaneous transluminal coronary angioplasty, coronary artery bypass graft, cerebral infarction, intracranial hemorrhage, subarachnoid hemorrhage, transient ischemic attacks within 3 months before initiation of the study 6) Heart failure patient whose NYHA functional classification is III or IV 7) Has history of administration of SGLT-2 within 1 month before initiation of the study 8) Pregnant, possibly pregnant, planned to become pregnant or nursing women 9) Has history of hypersensitivity to ipragliflozin or any other excipient of ipragliflozin 10) Are considered not eligible for the study by the attending doctor due to other reasons

发起方

Department of Cardiovascular Medicine, Saga University