Long-term Observation PMS for Afatinib
- Registration Number
- NCT02131259
- Lead Sponsor
- Boehringer Ingelheim
- Brief Summary
In Japan, post-approval execution of post marketing surveillance (PMS) is requested by the Japanese Pharmaceutical Affairs Law (J-PAL) in order to accumulate safety and efficacy data for reexamination. Reexamination period is defined by J-PAL. Eight years after approval of a new substance, results of PMS need to be submitted as a part of reexamination dossier to the Japanese regulatory authority, the Ministry of Health, Labour and Welfare (MHLW).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 1605
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Afatinib Afatinib dimaleate -
- Primary Outcome Measures
Name Time Method Incidence of Adverse Drug Reactions (ADRs) From first drug administration until 28 days after the last drug administration, up to 52 weeks. This outcome measure presents incidence of adverse drug reactions (ADRs). An ADR was defined as an AE if either the investigator or the sponsor (or both) assessed the causal relationship to GIOTRIF® Tablets either as "Yes", "Probably yes" or "Can't be denied".
The number of patients with Adverse Drug Reactions (ADRs): "Malignant progression" reported as ADRs were included.
- Secondary Outcome Measures
Name Time Method Objective Overall Response Based on Physician's Assessment [According to RECIST Version 1.1] 52 weeks. Objective overall response based on investigator's assessment (according to Response Evaluation Criteria in Solid Tumors (RECIST 1.1) for target lesions and assessed by MRI: complete response (CR) is the disappearance of all target lesions, a partial response (PR) is defined as at least a 30% decrease in the sum of the target lesion and stable disease (SD) is defined as fitting the criteria neither for progressive disease (PD) nor a PR. The population included the Tyrosine Kinase Inhibitor \[TKI\]-naïve patients and the TKI pre-treated patients.
Overall response was calculated with 95% Clopper-Pearson confidence interval.
OR = (CR+PR)/(CR+PR+SD+PD+Unknown)\*100.
Trial Locations
- Locations (432)
Boehringer Ingelheim Investigational Site 145
🇯🇵Adachi Tokyo, Japan
Boehringer Ingelheim Investigational Site 47
🇯🇵Akita Akita, Japan
Boehringer Ingelheim Investigational Site 44
🇯🇵Akita Akita, Japan
Boehringer Ingelheim Investigational Site 28
🇯🇵Aomori Aomori, Japan
Boehringer Ingelheim Investigational Site 115
🇯🇵Chiba Chiba, Japan
Boehringer Ingelheim Investigational Site 135
🇯🇵Chuo Tokyo, Japan
Boehringer Ingelheim Investigational Site 148
🇯🇵Edogawa Tokyo, Japan
Boehringer Ingelheim Investigational Site 394
🇯🇵Fukuoka Fukuoka, Japan
Boehringer Ingelheim Investigational Site 54
🇯🇵Higashiokitama Yamagata, Japan
Boehringer Ingelheim Investigational Site 31
🇯🇵Hirosaki Aomori, Japan
Boehringer Ingelheim Investigational Site 362
🇯🇵Hiroshima Hiroshima, Japan
Boehringer Ingelheim Investigational Site 360
🇯🇵Hiroshima Hiroshima, Japan
Boehringer Ingelheim Investigational Site 309
🇯🇵Ikeda Osaka, Japan
Boehringer Ingelheim Investigational Site 105
🇯🇵Iruma Saitama, Japan
Boehringer Ingelheim Investigational Site 289
🇯🇵Joyo Kyoto, Japan
Boehringer Ingelheim Investigational Site 423
🇯🇵Kagoshima Kagoshima, Japan
Boehringer Ingelheim Investigational Site 201
🇯🇵Kamakura Kanagawa, Japan
Boehringer Ingelheim Investigational Site 223
🇯🇵Kanazawa Ishikawa, Japan
Boehringer Ingelheim Investigational Site 225
🇯🇵Kanazawa Ishikawa, Japan
Boehringer Ingelheim Investigational Site 123
🇯🇵Kashiwa Chiba, Japan
Boehringer Ingelheim Investigational Site 106
🇯🇵Kawagoe Saitama, Japan
Boehringer Ingelheim Investigational Site 99
🇯🇵Kawaguchi Saitama, Japan
Boehringer Ingelheim Investigational Site 185
🇯🇵Kawasaki Kanagawa, Japan
Boehringer Ingelheim Investigational Site 377
🇯🇵Kita Kagawa, Japan
Boehringer Ingelheim Investigational Site 326
🇯🇵Kishiwada Osaka, Japan
Boehringer Ingelheim Investigational Site 328
🇯🇵Kobe Hyogo, Japan
Boehringer Ingelheim Investigational Site 179
🇯🇵Komae Tokyo, Japan
Boehringer Ingelheim Investigational Site 418
🇯🇵Oita Oita, Japan
Boehringer Ingelheim Investigational Site 62
🇯🇵Koriyama Fukushima, Japan
Boehringer Ingelheim Investigational Site 103
🇯🇵Koshigaya Saitama, Japan
Boehringer Ingelheim Investigational Site 287
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 24
🇯🇵Kushiro Hokkaido, Japan
Boehringer Ingelheim Investigational Site 413
🇯🇵Kumamoto Kumamoto, Japan
Boehringer Ingelheim Investigational Site 355
🇯🇵Kurashiki Okayama, Japan
Boehringer Ingelheim Investigational Site 278
🇯🇵Kuwana Mie, Japan
Boehringer Ingelheim Investigational Site 415
🇯🇵Kumamoto Kumamoto, Japan
Boehringer Ingelheim Investigational Site 285
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 177
🇯🇵Machida Tokyo, Japan
Boehringer Ingelheim Investigational Site 92
🇯🇵Maebashi Gumma, Japan
Boehringer Ingelheim Investigational Site 291
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 94
🇯🇵Maebashi Gumma, Japan
Boehringer Ingelheim Investigational Site 119
🇯🇵Matsudo Chiba, Japan
Boehringer Ingelheim Investigational Site 172
🇯🇵Mitaka Tokyo, Japan
Boehringer Ingelheim Investigational Site 346
🇯🇵Matsue Shimane, Japan
Boehringer Ingelheim Investigational Site 242
🇯🇵Matsumoto Nagano, Japan
Boehringer Ingelheim Investigational Site 347
🇯🇵Matsue Shimane, Japan
Boehringer Ingelheim Investigational Site 241
🇯🇵Matsumoto Nagano, Japan
Boehringer Ingelheim Investigational Site 249
🇯🇵Matsumoto Nagano, Japan
Boehringer Ingelheim Investigational Site 244
🇯🇵Matsumoto Nagano, Japan
Boehringer Ingelheim Investigational Site 280
🇯🇵Matsusaka Mie, Japan
Boehringer Ingelheim Investigational Site 381
🇯🇵Matsuyama Ehime, Japan
Boehringer Ingelheim Investigational Site 140
🇯🇵Minato Tokyo, Japan
Boehringer Ingelheim Investigational Site 75
🇯🇵Mito Ibaraki, Japan
Boehringer Ingelheim Investigational Site 138
🇯🇵Minato Tokyo, Japan
Boehringer Ingelheim Investigational Site 171
🇯🇵Mitaka Tokyo, Japan
Boehringer Ingelheim Investigational Site 139
🇯🇵Minato Tokyo, Japan
Boehringer Ingelheim Investigational Site 34
🇯🇵Morioka Iwate, Japan
Boehringer Ingelheim Investigational Site 405
🇯🇵Nagasaki Nagasaki, Japan
Boehringer Ingelheim Investigational Site 315
🇯🇵Moriguchi Osaka, Japan
Boehringer Ingelheim Investigational Site 283
🇯🇵Moriyama Shiga, Japan
Boehringer Ingelheim Investigational Site 237
🇯🇵Nagano Nagano, Japan
Boehringer Ingelheim Investigational Site 274
🇯🇵Nagakute Aichi, Japan
Boehringer Ingelheim Investigational Site 236
🇯🇵Nagano Nagano, Japan
Boehringer Ingelheim Investigational Site 341
🇯🇵Nara Nara, Japan
Boehringer Ingelheim Investigational Site 216
🇯🇵Niigata Niigata, Japan
Boehringer Ingelheim Investigational Site 211
🇯🇵Nagaoka Niigata, Japan
Boehringer Ingelheim Investigational Site 268
🇯🇵Nagoya Aichi, Japan
Boehringer Ingelheim Investigational Site 272
🇯🇵Nagoya Aichi, Japan
Boehringer Ingelheim Investigational Site 80
🇯🇵Naka Ibaraki, Japan
Boehringer Ingelheim Investigational Site 122
🇯🇵Narashino Chiba, Japan
Boehringer Ingelheim Investigational Site 169
🇯🇵Nerima Tokyo, Japan
Boehringer Ingelheim Investigational Site 217
🇯🇵Niigata Niigata, Japan
Boehringer Ingelheim Investigational Site 335
🇯🇵Nishinomiya Hyogo, Japan
Boehringer Ingelheim Investigational Site 334
🇯🇵Nishinomiya Hyogo, Japan
Boehringer Ingelheim Investigational Site 253
🇯🇵Ogaki Gifu, Japan
Boehringer Ingelheim Investigational Site 358
🇯🇵Onomichi Hiroshima, Japan
Boehringer Ingelheim Investigational Site 350
🇯🇵Okayama Okayama, Japan
Boehringer Ingelheim Investigational Site 301
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 207
🇯🇵Sagamihara Kanagawa, Japan
Boehringer Ingelheim Investigational Site 43
🇯🇵Osaki Miyagi, Japan
Boehringer Ingelheim Investigational Site 35
🇯🇵Oshu Iwate, Japan
Boehringer Ingelheim Investigational Site 156
🇯🇵Ota Tokyo, Japan
Boehringer Ingelheim Investigational Site 70
🇯🇵Ryugasaki Ibaraki, Japan
Boehringer Ingelheim Investigational Site 204
🇯🇵Sagamihara Kanagawa, Japan
Boehringer Ingelheim Investigational Site 239
🇯🇵Saku Nagano, Japan
Boehringer Ingelheim Investigational Site 10
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 7
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 9
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 11
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 15
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 36
🇯🇵Sendai Miyagi, Japan
Boehringer Ingelheim Investigational Site 275
🇯🇵Seto Aichi, Japan
Boehringer Ingelheim Investigational Site 98
🇯🇵Shibukawa Gumma, Japan
Boehringer Ingelheim Investigational Site 73
🇯🇵Sashima Ibaraki, Japan
Boehringer Ingelheim Investigational Site 38
🇯🇵Sendai Miyagi, Japan
Boehringer Ingelheim Investigational Site 83
🇯🇵Shimotsuga Tochigi, Japan
Boehringer Ingelheim Investigational Site 372
🇯🇵Shimonoseki Yamaguchi, Japan
Boehringer Ingelheim Investigational Site 152
🇯🇵Shinagawa Tokyo, Japan
Boehringer Ingelheim Investigational Site 163
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 259
🇯🇵Shizuoka Shizuoka, Japan
Boehringer Ingelheim Investigational Site 102
🇯🇵Soka Saitama, Japan
Boehringer Ingelheim Investigational Site 332
🇯🇵Sumoto Hyogo, Japan
Boehringer Ingelheim Investigational Site 314
🇯🇵Takatsuki Osaka, Japan
Boehringer Ingelheim Investigational Site 256
🇯🇵Sunto Shizuoka, Japan
Boehringer Ingelheim Investigational Site 90
🇯🇵Takasaki Gumma, Japan
Boehringer Ingelheim Investigational Site 374
🇯🇵Tokushima Tokushima, Japan
Boehringer Ingelheim Investigational Site 263
🇯🇵Toyohashi Aichi, Japan
Boehringer Ingelheim Investigational Site 254
🇯🇵Takayama Gifu, Japan
Boehringer Ingelheim Investigational Site 342
🇯🇵Tenri Nara, Japan
Boehringer Ingelheim Investigational Site 375
🇯🇵Tokushima Tokushima, Japan
Boehringer Ingelheim Investigational Site 6
🇯🇵Tomakomai Hokkaido, Japan
Boehringer Ingelheim Investigational Site 221
🇯🇵Toyama Toyama, Japan
Boehringer Ingelheim Investigational Site 279
🇯🇵Tsu Mie, Japan
Boehringer Ingelheim Investigational Site 101
🇯🇵Toda Saitama, Japan
Boehringer Ingelheim Investigational Site 373
🇯🇵Tokushima Tokushima, Japan
Boehringer Ingelheim Investigational Site 380
🇯🇵Toon Ehime, Japan
Boehringer Ingelheim Investigational Site 273
🇯🇵Toyota Aichi, Japan
Boehringer Ingelheim Investigational Site 55
🇯🇵Tsuruoka Yamagata, Japan
Boehringer Ingelheim Investigational Site 66
🇯🇵Tsuchiura Ibaraki, Japan
Boehringer Ingelheim Investigational Site 67
🇯🇵Tsuchiura Ibaraki, Japan
Boehringer Ingelheim Investigational Site 68
🇯🇵Tsuchiura Ibaraki, Japan
Boehringer Ingelheim Investigational Site 72
🇯🇵Tsukuba Ibaraki, Japan
Boehringer Ingelheim Investigational Site 370
🇯🇵Ube Yamaguchi, Japan
Boehringer Ingelheim Investigational Site 240
🇯🇵Ueda Nagano, Japan
Boehringer Ingelheim Investigational Site 431
🇯🇵Urasoe Okinawa, Japan
Boehringer Ingelheim Investigational Site 82
🇯🇵Utsunomiya Tochigi, Japan
Boehringer Ingelheim Investigational Site 404
🇯🇵Ureshino Saga, Japan
Boehringer Ingelheim Investigational Site 401
🇯🇵Yanagawa Fukuoka, Japan
Boehringer Ingelheim Investigational Site 50
🇯🇵Yamagata Yamagata, Japan
Boehringer Ingelheim Investigational Site 277
🇯🇵Yokkaichi Mie, Japan
Boehringer Ingelheim Investigational Site 188
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 187
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 319
🇯🇵Yao Osaka, Japan
Boehringer Ingelheim Investigational Site 49
🇯🇵Yamagata Yamagata, Japan
Boehringer Ingelheim Investigational Site 191
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 229
🇯🇵Yoshida Fukui, Japan
Boehringer Ingelheim Investigational Site 281
🇯🇵Ise Mie, Japan
Boehringer Ingelheim Investigational Site 388
🇯🇵Kitakyushu Fukuoka, Japan
Boehringer Ingelheim Investigational Site 389
🇯🇵Kitakyushu Fukuoka, Japan
Boehringer Ingelheim Investigational Site 74
🇯🇵Kasama Ibaraki, Japan
Boehringer Ingelheim Investigational Site 329
🇯🇵Kobe Hyogo, Japan
Boehringer Ingelheim Investigational Site 61
🇯🇵Koriyama Fukushima, Japan
Boehringer Ingelheim Investigational Site 288
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 292
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 91
🇯🇵Maebashi Gumma, Japan
Boehringer Ingelheim Investigational Site 293
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 93
🇯🇵Maebashi Gumma, Japan
Boehringer Ingelheim Investigational Site 378
🇯🇵Matsuyama Ehime, Japan
Boehringer Ingelheim Investigational Site 243
🇯🇵Matsumoto Nagano, Japan
Boehringer Ingelheim Investigational Site 379
🇯🇵Matsuyama Ehime, Japan
Boehringer Ingelheim Investigational Site 158
🇯🇵Meguro Tokyo, Japan
Boehringer Ingelheim Investigational Site 416
🇯🇵Minamata Kumamoto, Japan
Boehringer Ingelheim Investigational Site 137
🇯🇵Minato Tokyo, Japan
Boehringer Ingelheim Investigational Site 419
🇯🇵Miyazaki Miyazaki, Japan
Boehringer Ingelheim Investigational Site 420
🇯🇵Miyazaki Miyazaki, Japan
Boehringer Ingelheim Investigational Site 421
🇯🇵Miyazaki Miyazaki, Japan
Boehringer Ingelheim Investigational Site 33
🇯🇵Morioka Iwate, Japan
Boehringer Ingelheim Investigational Site 5
🇯🇵Muroran Hokkaido, Japan
Boehringer Ingelheim Investigational Site 238
🇯🇵Nagano Nagano, Japan
Boehringer Ingelheim Investigational Site 271
🇯🇵Nagoya Aichi, Japan
Boehringer Ingelheim Investigational Site 167
🇯🇵Nakano Tokyo, Japan
Boehringer Ingelheim Investigational Site 39
🇯🇵Natori Miyagi, Japan
Boehringer Ingelheim Investigational Site 215
🇯🇵Niigata Niigata, Japan
Boehringer Ingelheim Investigational Site 382
🇯🇵Niihama Ehime, Japan
Boehringer Ingelheim Investigational Site 336
🇯🇵Nishinomiya Hyogo, Japan
Boehringer Ingelheim Investigational Site 417
🇯🇵Oita Oita, Japan
Boehringer Ingelheim Investigational Site 22
🇯🇵Obihiro Hokkaido, Japan
Boehringer Ingelheim Investigational Site 353
🇯🇵Okayama Okayama, Japan
Boehringer Ingelheim Investigational Site 264
🇯🇵Okazaki Aichi, Japan
Boehringer Ingelheim Investigational Site 265
🇯🇵Okazaki Aichi, Japan
Boehringer Ingelheim Investigational Site 178
🇯🇵Ome Tokyo, Japan
Boehringer Ingelheim Investigational Site 295
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 298
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 304
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 305
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 307
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 96
🇯🇵Ota Gumma, Japan
Boehringer Ingelheim Investigational Site 153
🇯🇵Ota Tokyo, Japan
Boehringer Ingelheim Investigational Site 154
🇯🇵Ota Tokyo, Japan
Boehringer Ingelheim Investigational Site 4
🇯🇵Otaru Hokkaido, Japan
Boehringer Ingelheim Investigational Site 85
🇯🇵Otawara Tochigi, Japan
Boehringer Ingelheim Investigational Site 403
🇯🇵Saga Saga, Japan
Boehringer Ingelheim Investigational Site 205
🇯🇵Sagamihara Kanagawa, Japan
Boehringer Ingelheim Investigational Site 206
🇯🇵Sagamihara Kanagawa, Japan
Boehringer Ingelheim Investigational Site 323
🇯🇵Sakai Osaka, Japan
Boehringer Ingelheim Investigational Site 56
🇯🇵Sakata Yamagata, Japan
Boehringer Ingelheim Investigational Site 57
🇯🇵Sakata Yamagata, Japan
Boehringer Ingelheim Investigational Site 14
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 2
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 338
🇯🇵Sanda Hyogo, Japan
Boehringer Ingelheim Investigational Site 409
🇯🇵Sasebo Nagasaki, Japan
Boehringer Ingelheim Investigational Site 410
🇯🇵Sasebo Nagasaki, Japan
Boehringer Ingelheim Investigational Site 427
🇯🇵Satsumasendai Kagoshima, Japan
Boehringer Ingelheim Investigational Site 157
🇯🇵Shibuya Tokyo, Japan
Boehringer Ingelheim Investigational Site 408
🇯🇵Shimabara Nagasaki, Japan
Boehringer Ingelheim Investigational Site 369
🇯🇵Shimonoseki Yamaguchi, Japan
Boehringer Ingelheim Investigational Site 371
🇯🇵Shimonoseki Yamaguchi, Japan
Boehringer Ingelheim Investigational Site 84
🇯🇵Shimotsuga Tochigi, Japan
Boehringer Ingelheim Investigational Site 87
🇯🇵Shimotsuke Tochigi, Japan
Boehringer Ingelheim Investigational Site 88
🇯🇵Shimotsuke Tochigi, Japan
Boehringer Ingelheim Investigational Site 151
🇯🇵Shinagawa Tokyo, Japan
Boehringer Ingelheim Investigational Site 162
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 165
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 166
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 258
🇯🇵Shizuoka Shizuoka, Japan
Boehringer Ingelheim Investigational Site 310
🇯🇵Suita Osaka, Japan
Boehringer Ingelheim Investigational Site 311
🇯🇵Suita Osaka, Japan
Boehringer Ingelheim Investigational Site 146
🇯🇵Sumida Tokyo, Japan
Boehringer Ingelheim Investigational Site 245
🇯🇵Suwa Nagano, Japan
Boehringer Ingelheim Investigational Site 376
🇯🇵Takamatsu Kagawa, Japan
Boehringer Ingelheim Investigational Site 69
🇯🇵Tsukuba Ibaraki, Japan
Boehringer Ingelheim Investigational Site 290
🇯🇵Uji Kyoto, Japan
Boehringer Ingelheim Investigational Site 81
🇯🇵Utsunomiya Tochigi, Japan
Boehringer Ingelheim Investigational Site 344
🇯🇵Wakayama Wakayama, Japan
Boehringer Ingelheim Investigational Site 276
🇯🇵Yokkaichi Mie, Japan
Boehringer Ingelheim Investigational Site 51
🇯🇵Yamagata Yamagata, Japan
Boehringer Ingelheim Investigational Site 52
🇯🇵Yamagata Yamagata, Japan
Boehringer Ingelheim Investigational Site 412
🇯🇵Yamaga Kumamoto, Japan
Boehringer Ingelheim Investigational Site 197
🇯🇵Yamato Kanagawa, Japan
Boehringer Ingelheim Investigational Site 195
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 196
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 199
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 192
🇯🇵Yokosuka Kanagawa, Japan
Boehringer Ingelheim Investigational Site 193
🇯🇵Yokosuka Kanagawa, Japan
Boehringer Ingelheim Investigational Site 345
🇯🇵Yonago Tottori, Japan
Boehringer Ingelheim Investigational Site 230
🇯🇵Yoshida Fukui, Japan
Boehringer Ingelheim Investigational Site 400
🇯🇵Yukuhashi Fukuoka, Japan
Boehringer Ingelheim Investigational Site 64
🇯🇵Aizuwakamatsu Fukushima, Japan
Boehringer Ingelheim Investigational Site 429
🇯🇵Aira Kagoshima, Japan
Boehringer Ingelheim Investigational Site 333
🇯🇵Amagasaki Hyogo, Japan
Boehringer Ingelheim Investigational Site 45
🇯🇵Akita Akita, Japan
Boehringer Ingelheim Investigational Site 46
🇯🇵Akita Akita, Japan
Boehringer Ingelheim Investigational Site 266
🇯🇵Anjo Aichi, Japan
Boehringer Ingelheim Investigational Site 27
🇯🇵Aomori Aomori, Japan
Boehringer Ingelheim Investigational Site 127
🇯🇵Asahi Chiba, Japan
Boehringer Ingelheim Investigational Site 128
🇯🇵Asahi Chiba, Japan
Boehringer Ingelheim Investigational Site 18
🇯🇵Asahikawa Hokkaido, Japan
Boehringer Ingelheim Investigational Site 19
🇯🇵Asahikawa Hokkaido, Japan
Boehringer Ingelheim Investigational Site 20
🇯🇵Asahikawa Hokkaido, Japan
Boehringer Ingelheim Investigational Site 21
🇯🇵Asahikawa Hokkaido, Japan
Boehringer Ingelheim Investigational Site 198
🇯🇵Atsugi Kanagawa, Japan
Boehringer Ingelheim Investigational Site 142
🇯🇵Bunkyo Tokyo, Japan
Boehringer Ingelheim Investigational Site 294
🇯🇵Ayabe Kyoto, Japan
Boehringer Ingelheim Investigational Site 143
🇯🇵Bunkyo Tokyo, Japan
Boehringer Ingelheim Investigational Site 144
🇯🇵Bunkyo Tokyo, Japan
Boehringer Ingelheim Investigational Site 112
🇯🇵Chiba Chiba, Japan
Boehringer Ingelheim Investigational Site 114
🇯🇵Chiba Chiba, Japan
Boehringer Ingelheim Investigational Site 113
🇯🇵Chiba Chiba, Japan
Boehringer Ingelheim Investigational Site 116
🇯🇵Chiba Chiba, Japan
Boehringer Ingelheim Investigational Site 117
🇯🇵Chiba Chiba, Japan
Boehringer Ingelheim Investigational Site 402
🇯🇵Chikugo Fukuoka, Japan
Boehringer Ingelheim Investigational Site 16
🇯🇵Chitose Hokkaido, Japan
Boehringer Ingelheim Investigational Site 133
🇯🇵Chiyoda Tokyo, Japan
Boehringer Ingelheim Investigational Site 132
🇯🇵Chiyoda Tokyo, Japan
Boehringer Ingelheim Investigational Site 134
🇯🇵Chiyoda Tokyo, Japan
Boehringer Ingelheim Investigational Site 234
🇯🇵Chuo Yamanashi, Japan
Boehringer Ingelheim Investigational Site 136
🇯🇵Chuo Tokyo, Japan
Boehringer Ingelheim Investigational Site 48
🇯🇵Daisen Akita, Japan
Boehringer Ingelheim Investigational Site 235
🇯🇵Chuo Yamanashi, Japan
Boehringer Ingelheim Investigational Site 147
🇯🇵Edogawa Tokyo, Japan
Boehringer Ingelheim Investigational Site 173
🇯🇵Fuchu Tokyo, Japan
Boehringer Ingelheim Investigational Site 257
🇯🇵Fuji Shizuoka, Japan
Boehringer Ingelheim Investigational Site 260
🇯🇵Fujieda Shizuoka, Japan
Boehringer Ingelheim Investigational Site 97
🇯🇵Fujioka Gumma, Japan
Boehringer Ingelheim Investigational Site 231
🇯🇵Fukui Fukui, Japan
Boehringer Ingelheim Investigational Site 111
🇯🇵Fukaya Saitama, Japan
Boehringer Ingelheim Investigational Site 32
🇯🇵Hirosaki Aomori, Japan
Boehringer Ingelheim Investigational Site 393
🇯🇵Fukuoka Fukuoka, Japan
Boehringer Ingelheim Investigational Site 203
🇯🇵Fujisawa Kanagawa, Japan
Boehringer Ingelheim Investigational Site 232
🇯🇵Fukui Fukui, Japan
Boehringer Ingelheim Investigational Site 395
🇯🇵Fukuoka Fukuoka, Japan
Boehringer Ingelheim Investigational Site 396
🇯🇵Fukuoka Fukuoka, Japan
Boehringer Ingelheim Investigational Site 58
🇯🇵Fukushima Fukushima, Japan
Boehringer Ingelheim Investigational Site 399
🇯🇵Fukuoka Fukuoka, Japan
Boehringer Ingelheim Investigational Site 59
🇯🇵Fukushima Fukushima, Japan
Boehringer Ingelheim Investigational Site 60
🇯🇵Fukushima Fukushima, Japan
Boehringer Ingelheim Investigational Site 356
🇯🇵Fukuyama Hiroshima, Japan
Boehringer Ingelheim Investigational Site 357
🇯🇵Fukuyama Hiroshima, Japan
Boehringer Ingelheim Investigational Site 251
🇯🇵Gifu Gifu, Japan
Boehringer Ingelheim Investigational Site 29
🇯🇵Hachinohe Aomori, Japan
Boehringer Ingelheim Investigational Site 121
🇯🇵Funabashi Chiba, Japan
Boehringer Ingelheim Investigational Site 252
🇯🇵Gifu Gifu, Japan
Boehringer Ingelheim Investigational Site 432
🇯🇵Ginowan Okinawa, Japan
Boehringer Ingelheim Investigational Site 321
🇯🇵Habikino Osaka, Japan
Boehringer Ingelheim Investigational Site 30
🇯🇵Hachinohe Aomori, Japan
Boehringer Ingelheim Investigational Site 176
🇯🇵Hachioji Tokyo, Japan
Boehringer Ingelheim Investigational Site 209
🇯🇵Hadano Kanagawa, Japan
Boehringer Ingelheim Investigational Site 107
🇯🇵Hidaka Saitama, Japan
Boehringer Ingelheim Investigational Site 367
🇯🇵Hatsukaichi Hiroshima, Japan
Boehringer Ingelheim Investigational Site 349
🇯🇵Hamada Shimane, Japan
Boehringer Ingelheim Investigational Site 3
🇯🇵Hakodate Hokkaido, Japan
Boehringer Ingelheim Investigational Site 261
🇯🇵Hamamatsu Shizuoka, Japan
Boehringer Ingelheim Investigational Site 76
🇯🇵Higashiibaraki Ibaraki, Japan
Boehringer Ingelheim Investigational Site 318
🇯🇵Higashiosaka Osaka, Japan
Boehringer Ingelheim Investigational Site 316
🇯🇵Hirakata Osaka, Japan
Boehringer Ingelheim Investigational Site 53
🇯🇵Higashiokitama Yamagata, Japan
Boehringer Ingelheim Investigational Site 339
🇯🇵Himeji Hyogo, Japan
Boehringer Ingelheim Investigational Site 317
🇯🇵Hirakata Osaka, Japan
Boehringer Ingelheim Investigational Site 208
🇯🇵Hiratsuka Kanagawa, Japan
Boehringer Ingelheim Investigational Site 359
🇯🇵Hiroshima Hiroshima, Japan
Boehringer Ingelheim Investigational Site 361
🇯🇵Hiroshima Hiroshima, Japan
Boehringer Ingelheim Investigational Site 363
🇯🇵Hiroshima Hiroshima, Japan
Boehringer Ingelheim Investigational Site 79
🇯🇵Hitachi Ibaraki, Japan
Boehringer Ingelheim Investigational Site 78
🇯🇵Hitachinaka Ibaraki, Japan
Boehringer Ingelheim Investigational Site 364
🇯🇵Hiroshima Hiroshima, Japan
Boehringer Ingelheim Investigational Site 77
🇯🇵Hitachinaka Ibaraki, Japan
Boehringer Ingelheim Investigational Site 312
🇯🇵Ibaraki Osaka, Japan
Boehringer Ingelheim Investigational Site 120
🇯🇵Ichikawa Chiba, Japan
Boehringer Ingelheim Investigational Site 246
🇯🇵Iida Nagano, Japan
Boehringer Ingelheim Investigational Site 131
🇯🇵Ichihara Chiba, Japan
Boehringer Ingelheim Investigational Site 428
🇯🇵Isa Kagoshima, Japan
Boehringer Ingelheim Investigational Site 247
🇯🇵Iida Nagano, Japan
Boehringer Ingelheim Investigational Site 248
🇯🇵Ina Nagano, Japan
Boehringer Ingelheim Investigational Site 118
🇯🇵Inzai Chiba, Japan
Boehringer Ingelheim Investigational Site 368
🇯🇵Iwakuni Yamaguchi, Japan
Boehringer Ingelheim Investigational Site 407
🇯🇵Isahaya Nagasaki, Japan
Boehringer Ingelheim Investigational Site 168
🇯🇵Itabashi Tokyo, Japan
Boehringer Ingelheim Investigational Site 95
🇯🇵Isesaki Gumma, Japan
Boehringer Ingelheim Investigational Site 65
🇯🇵Iwaki Fukushima, Japan
Boehringer Ingelheim Investigational Site 17
🇯🇵Iwamizawa Hokkaido, Japan
Boehringer Ingelheim Investigational Site 324
🇯🇵Izumi Osaka, Japan
Boehringer Ingelheim Investigational Site 348
🇯🇵Izumo Shimane, Japan
Boehringer Ingelheim Investigational Site 255
🇯🇵Izunokuni Shizuoka, Japan
Boehringer Ingelheim Investigational Site 213
🇯🇵Joetsu Niigata, Japan
Boehringer Ingelheim Investigational Site 214
🇯🇵Joetsu Niigata, Japan
Boehringer Ingelheim Investigational Site 422
🇯🇵Kagoshima Kagoshima, Japan
Boehringer Ingelheim Investigational Site 425
🇯🇵Kagoshima Kagoshima, Japan
Boehringer Ingelheim Investigational Site 424
🇯🇵Kagoshima Kagoshima, Japan
Boehringer Ingelheim Investigational Site 340
🇯🇵Kakogawa Hyogo, Japan
Boehringer Ingelheim Investigational Site 426
🇯🇵Kagoshima Kagoshima, Japan
Boehringer Ingelheim Investigational Site 262
🇯🇵Kakegawa Shizuoka, Japan
Boehringer Ingelheim Investigational Site 202
🇯🇵Kamakura Kanagawa, Japan
Boehringer Ingelheim Investigational Site 130
🇯🇵Kamogawa Chiba, Japan
Boehringer Ingelheim Investigational Site 224
🇯🇵Kanazawa Ishikawa, Japan
Boehringer Ingelheim Investigational Site 226
🇯🇵Kanazawa Ishikawa, Japan
Boehringer Ingelheim Investigational Site 227
🇯🇵Kanazawa Ishikawa, Japan
Boehringer Ingelheim Investigational Site 343
🇯🇵Kashihara Nara, Japan
Boehringer Ingelheim Investigational Site 124
🇯🇵Kashiwa Chiba, Japan
Boehringer Ingelheim Investigational Site 125
🇯🇵Kashiwa Chiba, Japan
Boehringer Ingelheim Investigational Site 104
🇯🇵Kasukabe Saitama, Japan
Boehringer Ingelheim Investigational Site 100
🇯🇵Kawaguchi Saitama, Japan
Boehringer Ingelheim Investigational Site 184
🇯🇵Kawasaki Kanagawa, Japan
Boehringer Ingelheim Investigational Site 182
🇯🇵Kawasaki Kanagawa, Japan
Boehringer Ingelheim Investigational Site 183
🇯🇵Kawasaki Kanagawa, Japan
Boehringer Ingelheim Investigational Site 186
🇯🇵Kawasaki Kanagawa, Japan
Boehringer Ingelheim Investigational Site 129
🇯🇵Kisarazu Chiba, Japan
Boehringer Ingelheim Investigational Site 42
🇯🇵Kesennuma Miyagi, Japan
Boehringer Ingelheim Investigational Site 325
🇯🇵Kishiwada Osaka, Japan
Boehringer Ingelheim Investigational Site 110
🇯🇵Kitaadachi Saitama, Japan
Boehringer Ingelheim Investigational Site 387
🇯🇵Kitakyushu Fukuoka, Japan
Boehringer Ingelheim Investigational Site 390
🇯🇵Kitakyushu Fukuoka, Japan
Boehringer Ingelheim Investigational Site 25
🇯🇵Kitami Hokkaido, Japan
Boehringer Ingelheim Investigational Site 391
🇯🇵Kitakyushu Fukuoka, Japan
Boehringer Ingelheim Investigational Site 26
🇯🇵Kitami Hokkaido, Japan
Boehringer Ingelheim Investigational Site 180
🇯🇵Kiyose Tokyo, Japan
Boehringer Ingelheim Investigational Site 327
🇯🇵Kobe Hyogo, Japan
Boehringer Ingelheim Investigational Site 181
🇯🇵Kiyose Tokyo, Japan
Boehringer Ingelheim Investigational Site 331
🇯🇵Kobe Hyogo, Japan
Boehringer Ingelheim Investigational Site 384
🇯🇵Kochi Kochi, Japan
Boehringer Ingelheim Investigational Site 330
🇯🇵Kobe Hyogo, Japan
Boehringer Ingelheim Investigational Site 383
🇯🇵Kochi Kochi, Japan
Boehringer Ingelheim Investigational Site 385
🇯🇵Kochi Kochi, Japan
Boehringer Ingelheim Investigational Site 386
🇯🇵Kochi Kochi, Japan
Boehringer Ingelheim Investigational Site 174
🇯🇵Kodaira Tokyo, Japan
Boehringer Ingelheim Investigational Site 233
🇯🇵Kofu Yamanashi, Japan
Boehringer Ingelheim Investigational Site 397
🇯🇵Koga Fukuoka, Japan
Boehringer Ingelheim Investigational Site 398
🇯🇵Koga Fukuoka, Japan
Boehringer Ingelheim Investigational Site 228
🇯🇵Komatsu Ishikawa, Japan
Boehringer Ingelheim Investigational Site 149
🇯🇵Koto Tokyo, Japan
Boehringer Ingelheim Investigational Site 150
🇯🇵Koto Tokyo, Japan
Boehringer Ingelheim Investigational Site 63
🇯🇵Koriyama Fukushima, Japan
Boehringer Ingelheim Investigational Site 108
🇯🇵Kumagaya Saitama, Japan
Boehringer Ingelheim Investigational Site 109
🇯🇵Kumagaya Saitama, Japan
Boehringer Ingelheim Investigational Site 414
🇯🇵Kumamoto Kumamoto, Japan
Boehringer Ingelheim Investigational Site 352
🇯🇵Kurashiki Okayama, Japan
Boehringer Ingelheim Investigational Site 411
🇯🇵Kumamoto Kumamoto, Japan
Boehringer Ingelheim Investigational Site 365
🇯🇵Kure Hiroshima, Japan
Boehringer Ingelheim Investigational Site 366
🇯🇵Kure Hiroshima, Japan
Boehringer Ingelheim Investigational Site 286
🇯🇵Kyoto Kyoto, Japan
Boehringer Ingelheim Investigational Site 159
🇯🇵Meguro Tokyo, Japan
Boehringer Ingelheim Investigational Site 282
🇯🇵Moriyama Shiga, Japan
Boehringer Ingelheim Investigational Site 284
🇯🇵Nagahama Shiga, Japan
Boehringer Ingelheim Investigational Site 267
🇯🇵Nagoya Aichi, Japan
Boehringer Ingelheim Investigational Site 212
🇯🇵Nagaoka Niigata, Japan
Boehringer Ingelheim Investigational Site 269
🇯🇵Nagoya Aichi, Japan
Boehringer Ingelheim Investigational Site 210
🇯🇵Nagaoka Niigata, Japan
Boehringer Ingelheim Investigational Site 406
🇯🇵Nagasaki Nagasaki, Japan
Boehringer Ingelheim Investigational Site 170
🇯🇵Nerima Tokyo, Japan
Boehringer Ingelheim Investigational Site 270
🇯🇵Nagoya Aichi, Japan
Boehringer Ingelheim Investigational Site 218
🇯🇵Niigata Niigata, Japan
Boehringer Ingelheim Investigational Site 23
🇯🇵Obihiro Hokkaido, Japan
Boehringer Ingelheim Investigational Site 351
🇯🇵Okayama Okayama, Japan
Boehringer Ingelheim Investigational Site 296
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 299
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 303
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 302
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 306
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 155
🇯🇵Ota Tokyo, Japan
Boehringer Ingelheim Investigational Site 40
🇯🇵Sendai Miyagi, Japan
Boehringer Ingelheim Investigational Site 322
🇯🇵Sakai Osaka, Japan
Boehringer Ingelheim Investigational Site 126
🇯🇵Sakura Chiba, Japan
Boehringer Ingelheim Investigational Site 13
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 12
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 1
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 8
🇯🇵Sapporo Hokkaido, Japan
Boehringer Ingelheim Investigational Site 37
🇯🇵Sendai Miyagi, Japan
Boehringer Ingelheim Investigational Site 219
🇯🇵Shibata Niigata, Japan
Boehringer Ingelheim Investigational Site 430
🇯🇵Shimajiri Okinawa, Japan
Boehringer Ingelheim Investigational Site 160
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 161
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 164
🇯🇵Shinjuku Tokyo, Japan
Boehringer Ingelheim Investigational Site 41
🇯🇵Shiogama Miyagi, Japan
Boehringer Ingelheim Investigational Site 141
🇯🇵Taito Tokyo, Japan
Boehringer Ingelheim Investigational Site 175
🇯🇵Tachikawa Tokyo, Japan
Boehringer Ingelheim Investigational Site 222
🇯🇵Takaoka Toyama, Japan
Boehringer Ingelheim Investigational Site 337
🇯🇵Takarazuka Hyogo, Japan
Boehringer Ingelheim Investigational Site 89
🇯🇵Takasaki Gumma, Japan
Boehringer Ingelheim Investigational Site 313
🇯🇵Takatsuki Osaka, Japan
Boehringer Ingelheim Investigational Site 86
🇯🇵Tochigi Tochigi, Japan
Boehringer Ingelheim Investigational Site 71
🇯🇵Toride Ibaraki, Japan
Boehringer Ingelheim Investigational Site 220
🇯🇵Toyama Toyama, Japan
Boehringer Ingelheim Investigational Site 308
🇯🇵Toyonaka Osaka, Japan
Boehringer Ingelheim Investigational Site 354
🇯🇵Tsuyama Okayama, Japan
Boehringer Ingelheim Investigational Site 320
🇯🇵Yao Osaka, Japan
Boehringer Ingelheim Investigational Site 189
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 194
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 190
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 200
🇯🇵Yokohama Kanagawa, Japan
Boehringer Ingelheim Investigational Site 250
🇯🇵Matsumoto Nagano, Japan
Boehringer Ingelheim Investigational Site 392
🇯🇵Kitakyushu Fukuoka, Japan
Boehringer Ingelheim Investigational Site 297
🇯🇵Osaka Osaka, Japan
Boehringer Ingelheim Investigational Site 300
🇯🇵Osaka Osaka, Japan