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Sirolimus-Eluting BX VELOCITYTM Balloon-Expandable Stent in a Compassionate Use Registry (SECURE)

Phase 3
Completed
Conditions
Coronary Artery Disease
Interventions
Device: CYPHER Sirolimus-Eluting Coronary Stent
Registration Number
NCT00231244
Lead Sponsor
Cordis Corporation
Brief Summary

The objective of this study is to allow treatment with the sirolimus-eluting Bx VELOCITYTM stent in patients with a serious disease or condition for which there is no generally acceptable alternate treatment available.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
252
Inclusion Criteria
  1. Male or non-pregnant female patient minimum 18 years of age
  2. There is no alternative treatment for this patient as determined by the treating physician and an uninvolved cardiac surgeon;
  3. Target lesion is 2.50mm and 3.50mm in diameter (visual estimate);
  4. Target lesion is 45mm in length (visual estimate), treated with a maximum of three 18 mm stents;
Exclusion Criteria
  1. There is currently another method of treatment for the patient, including coronary artery bypass surgery (CABG) or brachytherapy;
  2. The study target lesion has definite or possible thrombus present by angiographic criteria.

Study & Design

Study Type
INTERVENTIONAL
Study Design
SINGLE_GROUP
Arm && Interventions
GroupInterventionDescription
1CYPHER Sirolimus-Eluting Coronary StentCYPHER Sirolimus-Eluting Coronary Stent
Primary Outcome Measures
NameTimeMethod
The primary endpoint of this study is a composite of Target Vessel Failure (TVF) defined as target vessel revascularization, myocardial infarction or cardiac death at 30 days, 6mo, 12mo, 2, 3, 4, and 5 years.30 days, 6mo, 12mo, 2, 3, 4, and 5 years
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (1)

Scripps Clinic and Research

🇺🇸

LaJolla, California, United States

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