跳至主要内容
临床试验/CTRI/2019/11/021847
CTRI/2019/11/021847招募中不适用

To study the effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) on Activities of Daily Living, Behavioral and Cognitive ability (A-B-C) of Parkinson disease Patients through a randomized controlled trial

Department of Biotechnology1 个研究点 分布在 1 个国家目标入组 130 人开始时间: 2019年4月11日最近更新:

试验速览

阶段
不适用
状态
招募中
发起方
入组人数
130
试验地点
1
主要终点
The effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cognition and Behavioural domains of Parkinson disease Patients.

研究概览

简要总结

Parkinsons Disease (PD) is the second most common neurodegenerative disorder and the most common movement disorder. The present research aims to study the efficacy of the Rtms using a neural navigator. This makes the work and therapeutic efficacy free from human error. Hence, if our research turns out to be positive at the completion of this project, then this program can be used for providing rTMS to patients suffering from Parkinson Disease along with other movement related disorders in order to improve their quality of life domains including cognition and behavioural aspect as they are found to be impaired which often gets under diagnosed and is found to have disabling effects on their lives. Hence, such treatment would help them restore optimal functional independence, moreover. It would also help in clinical and public health perspective. Since the existing management method (pharmacological) for various neurological disorders more often aims at relieving physical symptoms than neuropsychological symptoms. Hence such a study was planned where the quality of life is targeted for better community and social integration.

研究设计

研究类型
Interventional
分配方式
Computer generated randomization
盲法
Investigator Blinded

入排标准

年龄范围
50.00 Year(s) 至 90.00 Year(s)(—)
性别
All

入选标准

  • Consenting Individual
  • Patients diagnosed with idopathic Parkinson disease (As per UK Brain Bank Criteria)
  • Ability to sustain rTMS procedure for 2 weeks time period.
  • All education levels
  • Urban and rural
  • Right/left handedness.

排除标准

  • •Those not consenting •Any history of major psychiatric illness •Acute head injury •Patients with severe Depression on BDI-II (≥29).

结局指标

主要结局

The effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cognition and Behavioural domains of Parkinson disease Patients.

时间窗: baseline | 1 month | 3 months | 6 months

次要结局

  • Parkinson Disease- Quality of Life- 39(Parkinson Disease- Quality of Life- 39)

研究者

发起方
Department of Biotechnology
申办方类型
Government funding agency

研究点 (1)

Loading locations...

相似试验