How effective is the Repetitive Transcranial Magnetic Stimulation (rTMS) in improving Daily Living, Behaviour and Cognitive ability of Parkinson disease Patients: A Randomized Controlled Trial

Recruiting

• Conditions: Parkinsons disease,

• Registration Number: CTRI/2019/11/021847
• Lead Sponsor: Department of Biotechnology

Brief Summary

Parkinsons Disease (PD) is the second most common neurodegenerative disorder and the most common movement disorder. The present research aims to study the efficacy of the Rtms using a neural navigator. This makes the work and therapeutic efficacy free from human error. Hence, if our research turns out to be positive at the completion of this project, then this program can be used for providing rTMS to patients suffering from Parkinson Disease along with other movement related disorders in order to improve their quality of life domains including cognition and behavioural aspect as they are found to be impaired which often gets under diagnosed and is found to have disabling effects on their lives. Hence, such treatment would help them restore optimal functional independence, moreover. It would also help in clinical and public health perspective. Since the existing management method (pharmacological) for various neurological disorders more often aims at relieving physical symptoms than neuropsychological symptoms. Hence such a study was planned where the quality of life is targeted for better community and social integration.

Detailed Description

Not available

Study Timeline

• Study Start: 2019-04-11
• Last Update Posted: 2021-09-14

Recruitment & Eligibility

• Status: Open to Recruitment
• Sex: All
• Target Recruitment: 130

Inclusion Criteria

• Consenting Individual 2.
• Patients diagnosed with idopathic Parkinson disease (As per UK Brain Bank Criteria) 3.
• Ability to sustain rTMS procedure for 2 weeks time period.
• All education levels 4.
• Urban and rural 5.
• Right/left handedness.

Exclusion Criteria

•Those not consenting •Any history of major psychiatric illness •Acute head injury •Patients with severe Depression on BDI-II (≥29).

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The effectiveness of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cognition and Behavioural domains of Parkinson disease Patients.	baseline | 1 month | 3 months | 6 months

Secondary Outcome Measures

Name	Time	Method
Parkinson Disease- Quality of Life- 39	Parkinson Disease- Quality of Life- 39

Trial Locations

Locations (1)

All India Institute of Medical Sciences, New Delhi; 🇮🇳 Delhi, DELHI, India

All India Institute of Medical Sciences, New Delhi

🇮🇳Delhi, DELHI, India

Dr Ashima Nehra

Principal investigator

9810882765

ashimanwadhawan@gmail.com