Establishment of a Multi-Center Big Data System for Severe Infection and a Collaborative Network on Sepsis in Chinese Children
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 5,000
- 试验地点
- 1
- 主要终点
- survival rate
研究概览
简要总结
1. To research the current situation of severe infection in children in China, and to investigate the incidence, prognosis and disease burden of severe infection in children in different regions of China. 2. Establish the risk prediction model and diagnosi model of severe infection in children, and verify the accuracy of the model in multi-center; 3. To study the effectiveness and safety of different treatments in real diagnosis and treatment, and to evaluate the efficacy of subgroups under different ages and high risk factors.
详细描述
1.Children between 0 and 18 years old. 2.Severe pneumonia and/or sepsis.Patients were included who meet the guidline for diagnosis and treatment of community-acquired pneumonia in Children (2019) issued by the National Health Commission of the people's Republic of China and/or who meet the International Guide to the 2020 campaign to Save sepsis: management of septic shock and sepsis-related organ dysfunction in children. 3.notifiable infectious diseases.4.The researcher believes that he is not suitable to participate in other situations in this study.5.Participants in other clinical trials in the same period.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Prospective
入排标准
- 年龄范围
- 29 Days 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Children between 0 and 18 years old.
- •Severe pneumonia and/or sepsis.
排除标准
- •notifiable infectious diseases.
- •The researcher believes that he is not suitable to participate in other situations in this study.
- •Participants in other clinical trials in the same period.
研究组 & 干预措施
Severe infection
Children with severe infection in PICU
干预措施: Not applicable（Cohort study） (Other)
结局指标
主要结局
survival rate
时间窗: within 28 days after they discharged from PICU
The survival rate of children in 28 days after their discharged from PICU
次要结局
- length of stay in PICU(within 28 days after they discharged from PICU)