Implementation of a children’s hospital-wide central venous catheter insertion and maintenance bundle.

Completed

• Conditions: bloodstream infection, central venous catheter, prevention, children’s hospital, implementation, education

• Registration Number: NL-OMON28671
• Lead Sponsor: niversity Medical Center Rotterdam, Erasmus MC-Sophia Children's Hospital

Brief Summary

1: Buijs EA, Zwiers AJ, Ista E, Tibboel D, de Wildt SN. Biomarkers and clinical tools in critically ill children: are we heading toward tailored drug therapy? Biomark Med. 2012 Jun;6(3):239-57. PubMed PMID: 22731898.<br> 2: van Dijk M, Knoester H, van Beusekom BS, Ista E. Screening pediatric delirium with an adapted version of the Sophia Observation withdrawal Symptoms scale (SOS). Intensive Care Med. 2012 Mar;38(3):531-2. Epub 2011 Dec 9. PubMed PMID: 22160276; PubMed Central PMCID: PMC3286512.<br> 3: Ista E, Wildschut E, Tibboel D. Creating or preventing opioid addiction, finding the right dose. Pediatr Crit Care Med. 2011 Sep;12(5):590-2. PubMed PMID: 21897158.<br> 4: Valkenburg AJ, Boerlage AA, Ista E, Duivenvoorden HJ, Tibboel D, van Dijk M. The COMFORT-behavior scale is useful to assess pain and distress in 0- to 3-year-old children with Down syndrome. Pain. 2011 Sep;152(9):2059-64. Epub 2011 Jun 2. PubMed PMID: 21640484.<br> 5: Boerlage AA, Ista E, de Jong M, Tibboel D, van Dijk M. The COMFORT behavior scale: is a shorter observation period feasible?. Pediatr Crit Care Med. 2012 Mar;13(2):e124-5. PubMed PMID: 21499179.<br> 6: Duyndam A, Ista E, Houmes RJ, van Driel B, Reiss I, Tibboel D. Invasive ventilation modes in children: a systematic review and meta-analysis. Crit Care. 2011;15(1):R24. Epub 2011 Jan 17. Review. PubMed PMID: 21241490; PubMed Central PMCID: PMC3222058.<br> 7: Ista E, van Dijk M, Gischler S, de Leeuw M, Poley MJ, Tibboel D. Weaning of opioids and benzodiazepines at home after critical illness in infants: a cost-effective approach. J Opioid Manag. 2010 Jan-Feb;6(1):55-62. PubMed PMID: 20297615.<br> 8: Ista E, de Hoog M, Tibboel D, van Dijk M. Implementation of standard sedation management in paediatric intensive care: effective and feasible? J Clin Nurs. 2009 Sep;18(17):2511-20. Epub 2009 Jul 8. PubMed PMID: 19619202.<br> 9: Ista E, van Dijk M, de Hoog M, Tibboel D, Duivenvoorden HJ. Construction of the Sophia Observation withdrawal Symptoms-scale (SOS) for critically ill children. Intensive Care Med. 2009 Jun;35(6):1075-81. Epub 2009 Apr 15. PubMed PMID: 19367394.<br> 10: Ista E, van der Voort E. Assessment of withdrawal symptoms in pediatric intensive care patients, a new future? Pediatr Crit Care Med. 2008 Nov;9(6):654-5. PubMed PMID: 18997597.<br> 11: Ista E, van Dijk M, Gamel C, Tibboel D, de Hoog M. Withdrawal symptoms in critically ill children after long-term administration of sedatives and/or analgesics: a first evaluation. Crit Care Med. 2008 Aug;36(8):2427-32. PubMed PMID: 18596622.<br> 12: Ista E, van Dijk M, Gamel C, Tibboel D, de Hoog M. Withdrawal symptoms in children after long-term administration of sedatives and/or analgesics: a literature review. "Assessment remains troublesome". Intensive Care Med. 2007 Aug;33(8):1396-406. Epub 2007 Jun 1. Review. PubMed PMID: 17541548.<br> 13: Ista E, Joosten K. Nutritional assessment and enteral support of critically ill children. Crit Care Nurs Clin North Am. 2005 Dec;17(4):385-93, x. Review. PubMed PMID: 16344208.<br> 14: Ista E, van Dijk M, Tibboel D, de Hoog M. Assessment of sedation levels in pediatric intensive care patients can be improved by using the COMFORT "behavior" scale. Pediatr Crit Care Med. 2005 Jan;6(1):58-63. PubMed PMID: 15636661.

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 28 February 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 12840

Inclusion Criteria

All healthcare workers employed at the Erasmus MC-Sophia Children's Hospitial, Rotterdam, involved in patient care will participate.

Exclusion Criteria

Healthcare workers who are not involved in patient care.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Primary outcome measure is the number of catheter-associated infections per 1000 line-days.

Secondary Outcome Measures

Name	Time	Method
The process outcome is degree of adherence to use of these CVC bundles. A cost-effectiveness analysis is part of the study.