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Clinical Trials/NCT04618770
NCT04618770
Terminated
Not Applicable

A Prospective, Post-market, Multi-center Evaluation of the Clinical Outcomes of the Triathlon Total Knee System Using the Triathlon PSR Tibial Insert

Stryker Orthopaedics1 site in 1 country37 target enrollmentStarted: February 8, 2021Last updated:

Overview

Phase
Not Applicable
Status
Terminated
Enrollment
37
Locations
1
Primary Endpoint
Mean SF-36 Physical Component Score

Overview

Brief Summary

This study is a prospective, open-label, post-market, non-randomized, multi-center clinical evaluation of the Triathlon Total Knee System using the Triathlon PSR Tibial Insert for primary total knee arthroplasty (TKA) in a consecutive series of patients who meet the eligibility criteria. The SF-36 score of subjects receiving the Triathlon Total Knee with the Triathlon PSR insert is expected to be comparable with that of subjects receiving historical Triathlon PS cemented constructs.

Study Design

Study Type
Interventional
Allocation
Na
Intervention Model
Single Group
Primary Purpose
Treatment
Masking
None

Eligibility Criteria

Ages
18 Years to 75 Years (Adult, Older Adult)
Sex
All
Accepts Healthy Volunteers
No

Inclusion Criteria

  • Patient has signed an IRB/EC approved; study specific Informed Patient Consent Form.
  • Patient is a male or non-pregnant female, skeletally mature, age 18-75 years at time of study device implantation.
  • Patient has a diagnosis of Non-Inflammatory Degenerative Joint Disease (NIDJD).
  • Patient is a candidate for primary cemented total knee replacement.
  • Patient is willing and able to comply with postoperative scheduled clinical and radiographic evaluations and rehabilitation.

Exclusion Criteria

  • Patient has a Body Mass Index (BMI) \>
  • Patient is already participating in the study for a contralateral total knee replacement.
  • Patient has a diagnosis of avascular necrosis or inflammatory arthritis.
  • Patient has an active or suspected latent infection in or about the affected knee joint at time of study device implantation.
  • Patient has any mental or neuromuscular disorder which would create an unacceptable risk of prosthesis instability, prosthesis fixation failure, or complications in postoperative care.
  • Patient has a compromised bone stock which cannot provide adequate support to the prosthesis.
  • Patient is immunologically suppressed or receiving steroids in excess of normal physiological requirements (e.g. \> 30 days).
  • Patient is diagnosed with lumbar radicular pain.
  • Patient has severe instability of the knee joint secondary to the absence of collateral ligament integrity and function.
  • Patient has a known sensitivity to device materials.

Outcomes

Primary Outcomes

Mean SF-36 Physical Component Score

Time Frame: pre-operative, 6 weeks, 1 year

The SF-36 is a 36-item patient completed questionnaire to measure general health and well-being. It includes physical and mental status component sub scores; each ranging from 0-100. Low values represent a poor health state and high values represent a good health state.

Secondary Outcomes

  • Survivorship of Triathlon PSR Insert(1 Year)
  • Range of Motion(PreOp, 6 weeks, 1 year)
  • EuroQol-5 Dimension (EQ-5D)(PreOp, 6 week, 1 year)

Investigators

Sponsor Class
Industry
Responsible Party
Sponsor

Study Sites (1)

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