A clinical study of zinc supplementation in children with fast breathing and breathing difficulty

• Conditions: Severe acute lower respiratory tract infection

• Registration Number: CTRI/2009/091/000040

Brief Summary

This study is randomized, blinded study for evaluating the effect of zinc supplementation on duration of illness in children aged 2-24 months with severe acute lower respiratory tract infection. Primary outcome is time to be asymptomatic which is defined as resolution of all four of the following: respiratory distress, tachypnoea, hypoxia in room air and systemic danger signs

Detailed Description

Not available

Recruitment & Eligibility

• Sex: Not specified
• Target Recruitment: 0

Inclusion Criteria

Children aged 2-24 months presenting with tachypnoea and either chest retractions or one of the following danger signs: cyanosis, inability to feed/drink, lethargy and convulsions.

Exclusion Criteria

Children with concurrent diarrhea, severe malnutrition (weight for age <50% of reference value), congenital heart disease and those already on zinc supplements were excluded.

Study & Design

• Study Type: Not specified
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Time to be asymptomatic	defined as resolution of all four of the following: respiratory distress, tachypnoea, hypoxia in room air and systemic danger signs

Secondary Outcome Measures

Name	Time	Method
Duration of hospital stay	measured at discharge from hospital

Trial Locations

Locations (1)

Department of Pediatrics; 🇮🇳 Chandigarh, CHANDIGARH, India

Department of Pediatrics

🇮🇳Chandigarh, CHANDIGARH, India

Anuradha Bansal

Principal investigator

dranuradhabansal@yahoo.co.in