NL-OMON34971
Completed
Not Applicable
Role of hypercoagulability and hypofibrinolysis in the progression of hepatic fibrosis - Coagulation and Fibrosis
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- hepatic fibrosis
- Sponsor
- Erasmus MC, Universitair Medisch Centrum Rotterdam
- Enrollment
- 292
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. All participants of the Rotterdam Study (cohorts RS I\-5, RS II\-3 and RS III\-1\).
- •\- 1a. TE values \>12,5 kPa in the absence of steatosis will be considered as presence of advanced fibrosis. TE values \>10,5 kPa in the presence of steatosis will be considered as presence of advanced fibrosis (cases).
- •\- 1b. TE values \< 5 kPa will be considered as absence of fibrosis or presence of mild fibrosis (controls)
- •2\. Male or female, age \>\=18
- •3\. All subjects must have provided written informed consent.
Exclusion Criteria
- •a. Subjects with unreliable Fibroscan and/or US\-examination, as evaluated by the executing technician.
- •b. No informed consent
- •c. Subjects with decompensated cirrhosis
Outcomes
Primary Outcomes
Not specified
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