Preoperative exercise and education for patients undergoing major abdominal cancer surgery: A multicentre randomised controlled trial (PRIORITY Trial)
- Conditions
- Advanced gastrointestinal cancersRecurrent gastrointestinal cancersAbdominal cancersCancer - Bowel - Back passage (rectum) or large bowel (colon)Cancer - PancreaticCancer - Oesophageal (gullet)Cancer - StomachCancer - LiverCancer - Bowel - Small bowel (duodenum and ileum)Cancer - Bowel - Anal
- Registration Number
- ACTRN12621000617864
- Lead Sponsor
- The University of Sydney
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 210
To be eligible for the study, patients will be adults aged 18-80 years:
- Undergoing elective major surgery for advanced or recurrent gastrointestinal cancer (i.e. pelvic exenteration, cytoreductive surgery, oesophagectomy, hepatectomy, gastrectomy or pancreatectomy);
- Consult a gastrointestinal surgeon at least 4 weeks prior to planned surgery.
Patients will be excluded from the study if they have:
- Cognitive impairment such that they are unable to provide informed consent;
- Co-morbidity preventing participation in exercise and physical assessments (i.e. cardiorespiratory, musculoskeletal, neurological);
- Presenting with very poor functional capacity – Defined as a score of ‘zero’ (i.e. No) to all the following Duke Activity Status Index (DASI) (known collectively as the M-DASI-AQ): 1) Can you climb a flight of stairs or walk up a hill?; 2) Can you do heavy work around the house?; 3) Can you do yard work?; and 4) Can you participate in strenuous sports?;
- Inadequate English language to complete outcome measures;
- Currently participating in an exercise program.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method