MedPath

Osimertinib With or Without Bevacizumab as Initial Treatment for Patients With EGFR-Mutant Lung Cancer

Phase 3
Recruiting
Conditions
Advanced Lung Non-Squamous Non-Small Cell Carcinoma
Metastatic Lung Non-Squamous Non-Small Cell Carcinoma
Recurrent Lung Non-Squamous Non-Small Cell Carcinoma
Stage IIIB Lung Cancer AJCC v8
Stage IV Lung Cancer AJCC v8
Interventions
Procedure: Biospecimen Collection
Procedure: Computed Tomography
Procedure: Echocardiography Test
Procedure: Magnetic Resonance Imaging
Procedure: Multigated Acquisition Scan
Registration Number
NCT04181060
Lead Sponsor
National Cancer Institute (NCI)
Brief Summary

This phase III trial compares the effect of bevacizumab and osimertinib combination vs. osimertinib alone for the treatment of non-small cell lung cancer that has spread outside of the lungs (stage IIIB-IV) and has a change (mutation) in a gene called EGFR. The EGFR protein is involved in cell signaling pathways that control cell division and survival. Sometimes, mutations in the EGFR gene cause EGFR proteins to be made in higher than normal amounts on some types of cancer cells. This causes cancer cells to divide more rapidly. Osimertinib may stop the growth of tumor cells by blocking EGFR that is needed for cell growth in this type of cancer. Bevacizumab is in a class of medications called antiangiogenic agents. It works by stopping the formation of blood vessels that bring oxygen and nutrients to tumor. This may slow the growth and spread of tumor. Giving osimertinib with bevacizumab may control cancer for longer and help patients live longer as compared to osimertinib alone.

Detailed Description

PRIMARY OBJECTIVE:

I. To evaluate progression-free survival (PFS) of osimertinib (AZD9291) and bevacizumab versus osimertinib (AZD9291) alone as first-line treatment for patients with metastatic EGFR-mutant lung cancers.

SECONDARY OBJECTIVES:

I. To evaluate overall survival (OS). II. To evaluate best objective response rate and duration of objective response.

III. To evaluate time to central nervous system (CNS) progression and CNS PFS. IV. To evaluate toxicity of the combination regimen.

CORRELATIVE OBJECTIVES:

I. To characterize mechanisms of resistance to osimertinib (AZD9291) and osimertinib (AZD9291) with bevacizumab first-line therapy through post-progression circulating tumor-derived deoxyribonucleic acid (ctDNA).

II. To assess for ctDNA clearance on study treatment and associate ctDNA clearance with clinical outcomes.

OUTLINE: Patients are randomized to 1 of 2 arms.

ARM A: Patients receive osimertinib orally (PO) once daily (QD) on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.

ARM B: Patients receive osimertinib PO QD on days 1-21 and bevacizumab intravenously (IV) over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity.

Patients undergo echocardiography (ECHO), multigated acquisition scan (MUGA), computed tomography (CT) and may undergo magnetic resonance imaging (MRI) and blood and urine sample collection on study.

After completion of study treatment, patients are followed up every 3 months for 10 years.

Recruitment & Eligibility

Status
RECRUITING
Sex
All
Target Recruitment
300
Inclusion Criteria
  • Patient must have a pathologically-confirmed diagnosis of non-squamous, non-small cell lung cancer (NSCLC)

  • Patient must have advanced disease, defined as - either stage IV disease, stage IIIB disease not amenable to definitive multi-modality therapy, or recurrent disease after a prior diagnosis of stage I-III disease. All staging is via the American Joint Committee on Cancer (AJCC)/International Association for the Study of Lung Cancer (IASLC) 8th edition staging criteria

  • Patient must have somatic activating sensitizing mutation in EGFR (e.g. but not limited to Exon 19 deletion, L858R, E709X, G719X, exon 19 insertions, L861Q, S768I). Patients with non-sensitizing mutations in EGFR (EGFR exon 20 insertions) are not eligible. Test results originating from a Clinical Laboratory Improvement Act (CLIA)-certified or similarly accredited laboratory are acceptable; no specific assay is mandated. Plasma, cytology, or tumor tissue can be utilized for mutation testing

  • Patient must not have received any prior treatment with an anti-VEGF agent

    • NOTE: Prior treatment with an EGFR TKI is not allowed, however if a candidate for this study has already started osimertinib within 21 days prior to randomization, the exact osimertinib start date is known, and the patient had the required study baseline imaging completed prior to the osimertinib start date, the patient will be eligible
  • Patients that have received prior radiation therapy are eligible. Radiation (limited field stereotactic radiation or conventional radiation) must have been completed at least one week prior to study drug initiation and more extensive field radiation (i.e., whole-brain radiotherapy [WBRT]) must have been completed at least two weeks prior to drug initiation

  • Patient must not have any risk factors for anti-VEGF administration, specifically, hemoptysis, active cardiovascular disease, uncontrolled hypertension, significant proteinuria (screening urinalysis > 300 mg/dl) and tumor invading major blood vessels

  • Patient must have measurable disease. Baseline measurements of sites of disease must be obtained within 4 weeks prior to study randomization. If a potential target lesion is previously irradiated without subsequent growth and/or is radiated after the imaging from which baseline measurements are obtained, they cannot be included as target lesions, and additional target lesions are required to meet criteria for measurable disease

  • Patient must not have had any prior systemic treatment for metastatic disease

  • Patient must be ≥ 18 years of age

  • Patient must have an Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 2

  • Patient must not be pregnant or breast-feeding due to the potential harm to an unborn fetus and possible risk for adverse events in nursing infants with the treatment regimens being used

  • All females of childbearing potential must have a blood test or urine study within 14 days prior to randomization to rule out pregnancy

  • A female of childbearing potential is defined as any woman, regardless of sexual orientation or whether they have undergone tubal ligation, who meets the following criteria: 1) has achieved menarche at some point, 2) has not undergone a hysterectomy or bilateral oophorectomy; or 3) has not been naturally postmenopausal (amenorrhea following cancer therapy does not rule out childbearing potential) for at least 24 consecutive months (i.e., has had menses at any time in the preceding 24 consecutive months)

  • Patient of childbearing potential and sexually active males must not expect to conceive or father children by using accepted and effective method(s) of contraception or by abstaining from sexual intercourse for 2 weeks prior to the start of treatment, while on study treatment, and for

    • 6 weeks after the last dose of protocol treatment for female patients on the osimertinib (AZD9291) alone arm
    • 4 months after the last dose of protocol treatment for male patients on osimertinib (AZD9291) alone arm
    • 6 months after the last dose of protocol treatment for all patients on osimertinib (AZD9291) plus bevacizumab combination arm
    • NOTE: Female patients should also not breastfeed while on treatment and for 6 months after the last dose bevacizumab
  • Leukocytes >= 3,000/mcL (obtained =< 14 days prior to randomization)

  • Absolute neutrophil count >= 1,500/mcL (obtained =< 14 days prior to randomization)

  • Platelets >= 100,000/mcL (obtained =< 14 days prior to randomization)

  • Hemoglobin >= 9 g/dL (obtained =< 14 days prior to randomization)

  • Total bilirubin and creatinine =< 1.5 x institutional upper limit of normal (ULN) (obtained =< 14 days prior to randomization)

  • Aspartate aminotransferase (AST) (serum glutamic-oxaloacetic transaminase [SGOT])/alanine aminotransferase (ALT) (serum glutamate pyruvate transaminase [SGPT]) =< 2.5 x institutional ULN (obtained =< 14 days prior to randomization)

  • Human immunodeficiency virus (HIV)-infected patients on effective anti-retroviral therapy with undetectable viral load within 6 months are eligible for this trial

  • For patients with evidence of chronic hepatitis B virus (HBV) infection, the HBV viral load must be undetectable on suppressive therapy, if indicated

  • Patients with a history of hepatitis C virus (HCV) infection must have been treated and cured. For patients with HCV infection who are currently on treatment, they are eligible if they have an undetectable HCV viral load

  • Patients with treated brain metastases are eligible if neurologically stable without glucocorticoid therapy after the stated washout period from radiation therapy (RT) or surgery provided the metastatic lesions are non-hemorrhagic

  • Patients with untreated brain metastases or leptomeningeal disease are eligible if the treating physician determines that immediate CNS specific treatment is not required provided the metastatic lesions are non-hemorrhagic and are neurologically stable without glucocorticoid therapy

  • Patients with a prior or concurrent malignancy whose natural history or treatment does not have the potential to interfere with the safety or efficacy assessment of the investigational regimen are eligible for this trial

  • Patients with known history or current symptoms of cardiac disease, should have a clinical risk assessment of cardiac function using the New York Heart Association Functional Classification. To be eligible for this trial, patients should be class 2B or better

  • Patient must have the ability to understand and the willingness to sign a written informed consent document and comply with study requirements

  • Patient must not have had treatment with any investigational drug within five half-lives or 3 months (whichever is greater), prior to study initiation

  • Patient must not be currently receiving (or unable to stop use prior to receiving the first dose of study treatment) medications or herbal supplements known to be strong inducers of CYP3A4. For any patient currently receiving such inducers of CYP3A4, they must discontinue use prior to first dose of study treatment. All patients must try to avoid concomitant use of any medications, herbal supplements and/or ingestion of foods with known inducer effects on CYP3A4

  • Patient must not have any unresolved toxicities from prior therapy greater than Common Terminology Criteria for Adverse Events (CTCAE) grade 1 at the time of randomization, with the exception of alopecia and grade 2 prior platinum-therapy-related neuropathy

  • Patient must not have any evidence of severe or uncontrolled systemic diseases, including uncontrolled hypertension and active bleeding diatheses, which in the investigator's opinion makes it challenging for the patient to participate in the study. Screening for chronic conditions is not required

  • Patient must not have refractory nausea and vomiting, chronic gastrointestinal diseases, the inability to swallow the osimertinib tablets or previous significant bowel resection that would preclude adequate absorption of osimertinib

  • Patient must not have a medical history of interstitial lung disease, drug-induced interstitial lung disease, radiation pneumonitis which required steroid treatment, or any evidence of clinically active interstitial lung disease

  • Patient must not have a history of hypersensitivity to active or inactive excipients of osimertinib or drugs with a similar chemical structure or class to osimertinib

  • Patient must not have mean resting corrected QT interval (QTc) > 470 msec obtained from 3 electrocardiograms (ECGs), using the screening clinic ECG machine derived QTc value (using Bazett's correction)

  • Patient must not have any clinically important abnormalities in rhythm, conduction or morphology of resting ECG e.g. complete left bundle branch block, third degree heart block and second-degree heart block

  • Patient must not have any factors that increase the risk of QTc prolongation or risk of arrhythmic events such as heart failure, electrolyte abnormalities (including: potassium < lower limit of normal [LLN]; magnesium < LLN; calcium < LLN), congenital long QT syndrome, family history of long QT syndrome or unexplained sudden death under 40 years of age in first degree relatives or any concomitant medication known to prolong the QT interval and cause torsades de pointes

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Arm A (osimertinib)Biospecimen CollectionPatients receive osimertinib PO QD on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm A (osimertinib)Computed TomographyPatients receive osimertinib PO QD on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm A (osimertinib)Echocardiography TestPatients receive osimertinib PO QD on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm A (osimertinib)Magnetic Resonance ImagingPatients receive osimertinib PO QD on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm A (osimertinib)Multigated Acquisition ScanPatients receive osimertinib PO QD on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm A (osimertinib)OsimertinibPatients receive osimertinib PO QD on days 1-21. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)BevacizumabPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)Biospecimen CollectionPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)Computed TomographyPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)Echocardiography TestPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)Magnetic Resonance ImagingPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)Multigated Acquisition ScanPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Arm B (osimertinib, bevacizumab)OsimertinibPatients receive osimertinib PO QD on days 1-21 and bevacizumab IV over 30-90 minutes on day 1. Cycles repeat every 21 days in the absence of disease progression or unacceptable toxicity. Patients undergo ECHO, MUGA, CT and may undergo MRI and blood and urine sample collection on study.
Primary Outcome Measures
NameTimeMethod
Progression-free survival (PFS)From randomization to documented disease progression per Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 or death from any cause, whichever occurs first, assessed up to 10 years

Will be estimated using the Kaplan-Meier method, and Cox proportional hazards models will be used to estimate the treatment hazard ratios. PFS will use a logrank test stratified on the randomization stratification factors with a one-sided type I error rate of 2.5%.

Secondary Outcome Measures
NameTimeMethod
Overall survival (OS)From randomization to death from any cause, assessed up to 10 years

Will be estimated using the Kaplan-Meier method, and Cox proportional hazards models will be used to estimate the treatment hazard ratios. OS will be tested at the one-sided 10% level.

Best objective response rateUp to 10 years

Best objective response will be evaluated via RECIST 1.1 criteria. Will be compared using Fisher's exact tests with a one-sided type I error rate of 2.5%; multivariable logistic regression modeling will be used to adjust for the effect of any covariates that are associated with these categorical outcomes.

Time to central nervous system progressionFrom study randomization to evidence of central nervous system progressive disease, with death and progression as competing events, assessed up to 10 years

Will be estimated using competing risks methodology, adjusting for death and progression as competing events. Regular central nervous system imaging will occur when patients are on treatment. After they discontinue study treatment, central nervous system imaging will be symptom-prompted during follow up.

Central nervous system progression-free survivalFrom study randomization to evidence of central nervous system progressive disease or death from any cause, whichever occurs first, assessed up to 10 years

Will be estimated using the Kaplan-Meier method.

Incidence of adverse eventsUp to 30 days after the last administration of investigational agent

Toxicity will be determined using the Common Terminology Criteria for Adverse Events (CTCAE). Will be compared using Fisher's exact tests with a one-sided type I error rate of 2.5%; multivariable logistic regression modeling will be used to adjust for the effect of any covariates that are associated with these categorical outcomes.

Trial Locations

Locations (598)

UofL Health Medical Center Northeast

🇺🇸

Louisville, Kentucky, United States

Mount Carmel Grove City Hospital

🇺🇸

Grove City, Ohio, United States

Toledo Clinic Cancer Centers-Toledo

🇺🇸

Toledo, Ohio, United States

Dayton Physicians LLC - Troy

🇺🇸

Troy, Ohio, United States

Anchorage Associates in Radiation Medicine

🇺🇸

Anchorage, Alaska, United States

Anchorage Radiation Therapy Center

🇺🇸

Anchorage, Alaska, United States

Alaska Breast Care and Surgery LLC

🇺🇸

Anchorage, Alaska, United States

Mercy Hospital Fort Smith

🇺🇸

Fort Smith, Arkansas, United States

Alaska Oncology and Hematology LLC

🇺🇸

Anchorage, Alaska, United States

Alaska Women's Cancer Care

🇺🇸

Anchorage, Alaska, United States

Katmai Oncology Group

🇺🇸

Anchorage, Alaska, United States

Anchorage Oncology Centre

🇺🇸

Anchorage, Alaska, United States

Providence Alaska Medical Center

🇺🇸

Anchorage, Alaska, United States

Fairbanks Memorial Hospital

🇺🇸

Fairbanks, Alaska, United States

Providence Saint Joseph Medical Center/Disney Family Cancer Center

🇺🇸

Burbank, California, United States

Kaiser Permanente Dublin

🇺🇸

Dublin, California, United States

Cancer Center at Saint Joseph's

🇺🇸

Phoenix, Arizona, United States

CHI Saint Vincent Cancer Center Hot Springs

🇺🇸

Hot Springs, Arkansas, United States

NEA Baptist Memorial Hospital and Fowler Family Cancer Center - Jonesboro

🇺🇸

Jonesboro, Arkansas, United States

Kaiser Permanente-Deer Valley Medical Center

🇺🇸

Antioch, California, United States

Mission Hope Medical Oncology - Arroyo Grande

🇺🇸

Arroyo Grande, California, United States

Kaiser Permanente-Fremont

🇺🇸

Fremont, California, United States

Washington Hospital

🇺🇸

Fremont, California, United States

Kaiser Permanente-Fresno

🇺🇸

Fresno, California, United States

UC San Diego Moores Cancer Center

🇺🇸

La Jolla, California, United States

Kaiser Permanente-Modesto

🇺🇸

Modesto, California, United States

Kaiser Permanente-Oakland

🇺🇸

Oakland, California, United States

Stanford Cancer Institute Palo Alto

🇺🇸

Palo Alto, California, United States

Kaiser Permanente-Richmond

🇺🇸

Richmond, California, United States

Kaiser Permanente-Roseville

🇺🇸

Roseville, California, United States

Kaiser Permanente Downtown Commons

🇺🇸

Sacramento, California, United States

University of California Davis Comprehensive Cancer Center

🇺🇸

Sacramento, California, United States

Kaiser Permanente-South Sacramento

🇺🇸

Sacramento, California, United States

Salinas Valley Memorial

🇺🇸

Salinas, California, United States

Kaiser Permanente-San Francisco

🇺🇸

San Francisco, California, United States

Kaiser Permanente-Santa Teresa-San Jose

🇺🇸

San Jose, California, United States

Kaiser Permanente San Leandro

🇺🇸

San Leandro, California, United States

Pacific Central Coast Health Center-San Luis Obispo

🇺🇸

San Luis Obispo, California, United States

Kaiser San Rafael-Gallinas

🇺🇸

San Rafael, California, United States

Kaiser Permanente Medical Center - Santa Clara

🇺🇸

Santa Clara, California, United States

Mission Hope Medical Oncology - Santa Maria

🇺🇸

Santa Maria, California, United States

Kaiser Permanente-Santa Rosa

🇺🇸

Santa Rosa, California, United States

Kaiser Permanente-South San Francisco

🇺🇸

South San Francisco, California, United States

Kaiser Permanente-Stockton

🇺🇸

Stockton, California, United States

Kaiser Permanente Medical Center-Vacaville

🇺🇸

Vacaville, California, United States

Kaiser Permanente-Vallejo

🇺🇸

Vallejo, California, United States

Kaiser Permanente-Walnut Creek

🇺🇸

Walnut Creek, California, United States

Rocky Mountain Cancer Centers-Aurora

🇺🇸

Aurora, Colorado, United States

The Medical Center of Aurora

🇺🇸

Aurora, Colorado, United States

Boulder Community Foothills Hospital

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers-Boulder

🇺🇸

Boulder, Colorado, United States

Rocky Mountain Cancer Centers - Centennial

🇺🇸

Centennial, Colorado, United States

Penrose-Saint Francis Healthcare

🇺🇸

Colorado Springs, Colorado, United States

Rocky Mountain Cancer Centers-Penrose

🇺🇸

Colorado Springs, Colorado, United States

Kaiser Permanente-Franklin

🇺🇸

Denver, Colorado, United States

The Women's Imaging Center

🇺🇸

Denver, Colorado, United States

AdventHealth Porter

🇺🇸

Denver, Colorado, United States

Colorado Blood Cancer Institute

🇺🇸

Denver, Colorado, United States

Presbyterian - Saint Lukes Medical Center - Health One

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Midtown

🇺🇸

Denver, Colorado, United States

Rocky Mountain Cancer Centers-Rose

🇺🇸

Denver, Colorado, United States

Rose Medical Center

🇺🇸

Denver, Colorado, United States

Western Surgical Care

🇺🇸

Denver, Colorado, United States

Mercy Medical Center

🇺🇸

Durango, Colorado, United States

Southwest Oncology PC

🇺🇸

Durango, Colorado, United States

Mountain Blue Cancer Care Center - Swedish

🇺🇸

Englewood, Colorado, United States

Rocky Mountain Cancer Centers - Swedish

🇺🇸

Englewood, Colorado, United States

Swedish Medical Center

🇺🇸

Englewood, Colorado, United States

The Melanoma and Skin Cancer Institute

🇺🇸

Englewood, Colorado, United States

Banner North Colorado Medical Center

🇺🇸

Greeley, Colorado, United States

Kaiser Permanente-Rock Creek

🇺🇸

Lafayette, Colorado, United States

Rocky Mountain Cancer Centers-Lakewood

🇺🇸

Lakewood, Colorado, United States

Saint Anthony Hospital

🇺🇸

Lakewood, Colorado, United States

Rocky Mountain Cancer Centers-Littleton

🇺🇸

Littleton, Colorado, United States

AdventHealth Littleton

🇺🇸

Littleton, Colorado, United States

Kaiser Permanente-Lone Tree

🇺🇸

Lone Tree, Colorado, United States

Rocky Mountain Cancer Centers-Sky Ridge

🇺🇸

Lone Tree, Colorado, United States

Sky Ridge Medical Center

🇺🇸

Lone Tree, Colorado, United States

Longmont United Hospital

🇺🇸

Longmont, Colorado, United States

Rocky Mountain Cancer Centers-Longmont

🇺🇸

Longmont, Colorado, United States

Banner McKee Medical Center

🇺🇸

Loveland, Colorado, United States

AdventHealth Parker

🇺🇸

Parker, Colorado, United States

Saint Mary Corwin Medical Center

🇺🇸

Pueblo, Colorado, United States

Rocky Mountain Cancer Centers-Thornton

🇺🇸

Thornton, Colorado, United States

Smilow Cancer Hospital-Derby Care Center

🇺🇸

Derby, Connecticut, United States

Smilow Cancer Hospital Care Center-Fairfield

🇺🇸

Fairfield, Connecticut, United States

Smilow Cancer Hospital Care Center - Guilford

🇺🇸

Guilford, Connecticut, United States

Hartford Hospital

🇺🇸

Hartford, Connecticut, United States

Midstate Medical Center

🇺🇸

Meriden, Connecticut, United States

Yale University

🇺🇸

New Haven, Connecticut, United States

Yale-New Haven Hospital North Haven Medical Center

🇺🇸

North Haven, Connecticut, United States

Smilow Cancer Hospital-Orange Care Center

🇺🇸

Orange, Connecticut, United States

Smilow Cancer Hospital Care Center at Long Ridge

🇺🇸

Stamford, Connecticut, United States

Stamford Hospital/Bennett Cancer Center

🇺🇸

Stamford, Connecticut, United States

Smilow Cancer Hospital Care Center at Glastonbury

🇺🇸

Glastonbury, Connecticut, United States

Smilow Cancer Hospital Care Center at Greenwich

🇺🇸

Greenwich, Connecticut, United States

Smilow Cancer Hospital Care Center at Saint Francis

🇺🇸

Hartford, Connecticut, United States

The Hospital of Central Connecticut

🇺🇸

New Britain, Connecticut, United States

Smilow Cancer Hospital-Torrington Care Center

🇺🇸

Torrington, Connecticut, United States

Smilow Cancer Hospital Care Center-Trumbull

🇺🇸

Trumbull, Connecticut, United States

Smilow Cancer Hospital-Waterbury Care Center

🇺🇸

Waterbury, Connecticut, United States

Smilow Cancer Hospital Care Center - Waterford

🇺🇸

Waterford, Connecticut, United States

Beebe Medical Center

🇺🇸

Lewes, Delaware, United States

Medical Oncology Hematology Consultants PA

🇺🇸

Newark, Delaware, United States

Beebe Health Campus

🇺🇸

Rehoboth Beach, Delaware, United States

TidalHealth Nanticoke / Allen Cancer Center

🇺🇸

Seaford, Delaware, United States

Beebe South Coastal Health Campus

🇺🇸

Millville, Delaware, United States

Christiana Care Health System-Christiana Hospital

🇺🇸

Newark, Delaware, United States

Delaware Clinical and Laboratory Physicians PA

🇺🇸

Newark, Delaware, United States

Helen F Graham Cancer Center

🇺🇸

Newark, Delaware, United States

Christiana Care Health System-Wilmington Hospital

🇺🇸

Wilmington, Delaware, United States

Holy Cross Hospital

🇺🇸

Fort Lauderdale, Florida, United States

Emory University Hospital Midtown

🇺🇸

Atlanta, Georgia, United States

Emory University Hospital/Winship Cancer Institute

🇺🇸

Atlanta, Georgia, United States

Lewis Cancer and Research Pavilion at Saint Joseph's/Candler

🇺🇸

Savannah, Georgia, United States

Hawaii Cancer Care - Westridge

🇺🇸

'Aiea, Hawaii, United States

Pali Momi Medical Center

🇺🇸

'Aiea, Hawaii, United States

Queen's Cancer Center - Pearlridge

🇺🇸

'Aiea, Hawaii, United States

The Cancer Center of Hawaii-Pali Momi

🇺🇸

'Aiea, Hawaii, United States

Hawaii Cancer Care Inc - Waterfront Plaza

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Cenrer - POB I

🇺🇸

Honolulu, Hawaii, United States

Queen's Medical Center

🇺🇸

Honolulu, Hawaii, United States

Straub Clinic and Hospital

🇺🇸

Honolulu, Hawaii, United States

University of Hawaii Cancer Center

🇺🇸

Honolulu, Hawaii, United States

Kuakini Medical Center

🇺🇸

Honolulu, Hawaii, United States

Queen's Cancer Center - Kuakini

🇺🇸

Honolulu, Hawaii, United States

The Cancer Center of Hawaii-Liliha

🇺🇸

Honolulu, Hawaii, United States

Kaiser Permanente Moanalua Medical Center

🇺🇸

Honolulu, Hawaii, United States

Kapiolani Medical Center for Women and Children

🇺🇸

Honolulu, Hawaii, United States

Wilcox Memorial Hospital and Kauai Medical Clinic

🇺🇸

Lihue, Hawaii, United States

Saint Alphonsus Cancer Care Center-Boise

🇺🇸

Boise, Idaho, United States

Saint Luke's Cancer Institute - Boise

🇺🇸

Boise, Idaho, United States

Saint Alphonsus Cancer Care Center-Caldwell

🇺🇸

Caldwell, Idaho, United States

Kootenai Health - Coeur d'Alene

🇺🇸

Coeur d'Alene, Idaho, United States

Walter Knox Memorial Hospital

🇺🇸

Emmett, Idaho, United States

Saint Luke's Cancer Institute - Fruitland

🇺🇸

Fruitland, Idaho, United States

Idaho Urologic Institute-Meridian

🇺🇸

Meridian, Idaho, United States

Saint Luke's Cancer Institute - Meridian

🇺🇸

Meridian, Idaho, United States

Saint Alphonsus Cancer Care Center-Nampa

🇺🇸

Nampa, Idaho, United States

Saint Luke's Cancer Institute - Nampa

🇺🇸

Nampa, Idaho, United States

Kootenai Clinic Cancer Services - Post Falls

🇺🇸

Post Falls, Idaho, United States

Kootenai Clinic Cancer Services - Sandpoint

🇺🇸

Sandpoint, Idaho, United States

Saint Luke's Cancer Institute - Twin Falls

🇺🇸

Twin Falls, Idaho, United States

OSF Saint Anthony's Health Center

🇺🇸

Alton, Illinois, United States

Rush - Copley Medical Center

🇺🇸

Aurora, Illinois, United States

Illinois CancerCare-Bloomington

🇺🇸

Bloomington, Illinois, United States

Illinois CancerCare-Canton

🇺🇸

Canton, Illinois, United States

Memorial Hospital of Carbondale

🇺🇸

Carbondale, Illinois, United States

SIH Cancer Institute

🇺🇸

Carterville, Illinois, United States

Illinois CancerCare-Carthage

🇺🇸

Carthage, Illinois, United States

Centralia Oncology Clinic

🇺🇸

Centralia, Illinois, United States

Northwestern University

🇺🇸

Chicago, Illinois, United States

Jesse Brown Veterans Affairs Medical Center

🇺🇸

Chicago, Illinois, United States

University of Illinois

🇺🇸

Chicago, Illinois, United States

Swedish Covenant Hospital

🇺🇸

Chicago, Illinois, United States

Carle at The Riverfront

🇺🇸

Danville, Illinois, United States

Cancer Care Specialists of Illinois - Decatur

🇺🇸

Decatur, Illinois, United States

Decatur Memorial Hospital

🇺🇸

Decatur, Illinois, United States

Northwestern Medicine Cancer Center Kishwaukee

🇺🇸

DeKalb, Illinois, United States

Illinois CancerCare-Dixon

🇺🇸

Dixon, Illinois, United States

Carle Physician Group-Effingham

🇺🇸

Effingham, Illinois, United States

Crossroads Cancer Center

🇺🇸

Effingham, Illinois, United States

Illinois CancerCare-Eureka

🇺🇸

Eureka, Illinois, United States

Illinois CancerCare-Galesburg

🇺🇸

Galesburg, Illinois, United States

Western Illinois Cancer Treatment Center

🇺🇸

Galesburg, Illinois, United States

Northwestern Medicine Cancer Center Delnor

🇺🇸

Geneva, Illinois, United States

Northwestern Medicine Glenview Outpatient Center

🇺🇸

Glenview, Illinois, United States

Northwestern Medicine Grayslake Outpatient Center

🇺🇸

Grayslake, Illinois, United States

Ingalls Memorial Hospital

🇺🇸

Harvey, Illinois, United States

Illinois CancerCare-Kewanee Clinic

🇺🇸

Kewanee, Illinois, United States

Northwestern Medicine Lake Forest Hospital

🇺🇸

Lake Forest, Illinois, United States

Illinois CancerCare-Macomb

🇺🇸

Macomb, Illinois, United States

Carle Physician Group-Mattoon/Charleston

🇺🇸

Mattoon, Illinois, United States

SSM Health Good Samaritan

🇺🇸

Mount Vernon, Illinois, United States

Cancer Care Center of O'Fallon

🇺🇸

O'Fallon, Illinois, United States

Northwestern Medicine Orland Park

🇺🇸

Orland Park, Illinois, United States

Illinois CancerCare-Ottawa Clinic

🇺🇸

Ottawa, Illinois, United States

Illinois CancerCare-Peoria

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Pekin

🇺🇸

Pekin, Illinois, United States

Methodist Medical Center of Illinois

🇺🇸

Peoria, Illinois, United States

Illinois CancerCare-Peru

🇺🇸

Peru, Illinois, United States

Valley Radiation Oncology

🇺🇸

Peru, Illinois, United States

Illinois CancerCare-Princeton

🇺🇸

Princeton, Illinois, United States

Southern Illinois University School of Medicine

🇺🇸

Springfield, Illinois, United States

Springfield Clinic

🇺🇸

Springfield, Illinois, United States

Springfield Memorial Hospital

🇺🇸

Springfield, Illinois, United States

Southwest Illinois Health Services LLP

🇺🇸

Swansea, Illinois, United States

Carle Cancer Center

🇺🇸

Urbana, Illinois, United States

The Carle Foundation Hospital

🇺🇸

Urbana, Illinois, United States

Northwestern Medicine Cancer Center Warrenville

🇺🇸

Warrenville, Illinois, United States

Illinois CancerCare - Washington

🇺🇸

Washington, Illinois, United States

Rush-Copley Healthcare Center

🇺🇸

Yorkville, Illinois, United States

Northwest Cancer Center - Main Campus

🇺🇸

Crown Point, Indiana, United States

Northwest Oncology LLC

🇺🇸

Dyer, Indiana, United States

Northwest Cancer Center - Hobart

🇺🇸

Hobart, Indiana, United States

Saint Mary Medical Center

🇺🇸

Hobart, Indiana, United States

Saint Catherine Hospital

🇺🇸

Indianapolis, Indiana, United States

The Community Hospital

🇺🇸

Munster, Indiana, United States

Women's Diagnostic Center - Munster

🇺🇸

Munster, Indiana, United States

Reid Health

🇺🇸

Richmond, Indiana, United States

Northwest Cancer Center - Valparaiso

🇺🇸

Valparaiso, Indiana, United States

Mary Greeley Medical Center

🇺🇸

Ames, Iowa, United States

McFarland Clinic - Ames

🇺🇸

Ames, Iowa, United States

UI Health Care Mission Cancer and Blood - Ankeny Clinic

🇺🇸

Ankeny, Iowa, United States

McFarland Clinic - Boone

🇺🇸

Boone, Iowa, United States

Saint Anthony Regional Hospital

🇺🇸

Carroll, Iowa, United States

Jewish Hospital Medical Center South

🇺🇸

Shepherdsville, Kentucky, United States

Mercy Cancer Center-West Lakes

🇺🇸

Clive, Iowa, United States

UI Health Care Mission Cancer and Blood - West Des Moines Clinic

🇺🇸

Clive, Iowa, United States

Alegent Health Mercy Hospital

🇺🇸

Council Bluffs, Iowa, United States

Greater Regional Medical Center

🇺🇸

Creston, Iowa, United States

Iowa Methodist Medical Center

🇺🇸

Des Moines, Iowa, United States

Saint Charles Health System-Redmond

🇺🇸

Redmond, Oregon, United States

UI Health Care Mission Cancer and Blood - Des Moines Clinic

🇺🇸

Des Moines, Iowa, United States

Broadlawns Medical Center

🇺🇸

Des Moines, Iowa, United States

Mercy Medical Center - Des Moines

🇺🇸

Des Moines, Iowa, United States

UI Health Care Mission Cancer and Blood - Laurel Clinic

🇺🇸

Des Moines, Iowa, United States

Iowa Lutheran Hospital

🇺🇸

Des Moines, Iowa, United States

McFarland Clinic - Trinity Cancer Center

🇺🇸

Fort Dodge, Iowa, United States

Trinity Regional Medical Center

🇺🇸

Fort Dodge, Iowa, United States

McFarland Clinic - Jefferson

🇺🇸

Jefferson, Iowa, United States

McFarland Clinic - Marshalltown

🇺🇸

Marshalltown, Iowa, United States

UI Health Care Mission Cancer and Blood - Waukee Clinic

🇺🇸

Waukee, Iowa, United States

Methodist West Hospital

🇺🇸

West Des Moines, Iowa, United States

Mercy Medical Center-West Lakes

🇺🇸

West Des Moines, Iowa, United States

Central Care Cancer Center - Garden City

🇺🇸

Garden City, Kansas, United States

Central Care Cancer Center - Great Bend

🇺🇸

Great Bend, Kansas, United States

Cancer Center of Kansas-Wichita Medical Arts Tower

🇺🇸

Wichita, Kansas, United States

Ascension Via Christi Hospitals Wichita

🇺🇸

Wichita, Kansas, United States

Cancer Center of Kansas - Wichita

🇺🇸

Wichita, Kansas, United States

Flaget Memorial Hospital

🇺🇸

Bardstown, Kentucky, United States

Commonwealth Cancer Center-Corbin

🇺🇸

Corbin, Kentucky, United States

Saint Joseph Radiation Oncology Resource Center

🇺🇸

Lexington, Kentucky, United States

Saint Joseph Hospital East

🇺🇸

Lexington, Kentucky, United States

Saint Joseph London

🇺🇸

London, Kentucky, United States

Jewish Hospital

🇺🇸

Louisville, Kentucky, United States

Saints Mary and Elizabeth Hospital

🇺🇸

Louisville, Kentucky, United States

Walter Reed National Military Medical Center

🇺🇸

Bethesda, Maryland, United States

Beverly Hospital

🇺🇸

Beverly, Massachusetts, United States

Lahey Hospital and Medical Center

🇺🇸

Burlington, Massachusetts, United States

Addison Gilbert Hospital

🇺🇸

Gloucester, Massachusetts, United States

Lahey Medical Center-Peabody

🇺🇸

Peabody, Massachusetts, United States

Beth Israel Deaconess Medical Center/Winchester Center for Cancer Care

🇺🇸

Winchester, Massachusetts, United States

UMass Memorial Medical Center - University Campus

🇺🇸

Worcester, Massachusetts, United States

Hickman Cancer Center

🇺🇸

Adrian, Michigan, United States

Trinity Health Saint Joseph Mercy Hospital Ann Arbor

🇺🇸

Ann Arbor, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Brighton

🇺🇸

Brighton, Michigan, United States

Trinity Health Medical Center - Brighton

🇺🇸

Brighton, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Canton

🇺🇸

Canton, Michigan, United States

Trinity Health Medical Center - Canton

🇺🇸

Canton, Michigan, United States

Caro Cancer Center

🇺🇸

Caro, Michigan, United States

Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Trinity Health IHA Medical Group Hematology Oncology - Chelsea Hospital

🇺🇸

Chelsea, Michigan, United States

Hematology Oncology Consultants-Clarkston

🇺🇸

Clarkston, Michigan, United States

Newland Medical Associates-Clarkston

🇺🇸

Clarkston, Michigan, United States

Corewell Health Dearborn Hospital

🇺🇸

Dearborn, Michigan, United States

Henry Ford Health Saint John Hospital

🇺🇸

Detroit, Michigan, United States

Henry Ford River District Hospital

🇺🇸

East China Township, Michigan, United States

Northwest Medical Specialties PLLC

🇺🇸

Tacoma, Washington, United States

Cancer Hematology Centers - Flint

🇺🇸

Flint, Michigan, United States

Genesee Hematology Oncology PC

🇺🇸

Flint, Michigan, United States

Genesys Hurley Cancer Institute

🇺🇸

Flint, Michigan, United States

Hurley Medical Center

🇺🇸

Flint, Michigan, United States

Henry Ford Saint John Hospital - Academic

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Breast

🇺🇸

Grosse Pointe Woods, Michigan, United States

Henry Ford Saint John Hospital - Van Elslander

🇺🇸

Grosse Pointe Woods, Michigan, United States

University of Michigan Health - Sparrow Lansing

🇺🇸

Lansing, Michigan, United States

Hope Cancer Clinic

🇺🇸

Livonia, Michigan, United States

Trinity Health Saint Mary Mercy Livonia Hospital

🇺🇸

Livonia, Michigan, United States

Henry Ford Saint John Hospital - Macomb Medical

🇺🇸

Macomb, Michigan, United States

Henry Ford Warren Hospital - Breast Macomb

🇺🇸

Macomb, Michigan, United States

Saint Mary's Oncology/Hematology Associates of Marlette

🇺🇸

Marlette, Michigan, United States

Toledo Clinic Cancer Centers-Monroe

🇺🇸

Monroe, Michigan, United States

Hope Cancer Center

🇺🇸

Pontiac, Michigan, United States

Michigan Healthcare Professionals Pontiac

🇺🇸

Pontiac, Michigan, United States

Newland Medical Associates-Pontiac

🇺🇸

Pontiac, Michigan, United States

Trinity Health Saint Joseph Mercy Oakland Hospital

🇺🇸

Pontiac, Michigan, United States

Henry Ford Rochester Hospital

🇺🇸

Rochester Hills, Michigan, United States

Corewell Health William Beaumont University Hospital

🇺🇸

Royal Oak, Michigan, United States

MyMichigan Medical Center Saginaw

🇺🇸

Saginaw, Michigan, United States

Oncology Hematology Associates of Saginaw Valley PC

🇺🇸

Saginaw, Michigan, United States

Bhadresh Nayak MD PC-Sterling Heights

🇺🇸

Sterling Heights, Michigan, United States

MyMichigan Medical Center Tawas

🇺🇸

Tawas City, Michigan, United States

Corewell Health Beaumont Troy Hospital

🇺🇸

Troy, Michigan, United States

Advanced Breast Care Center PLLC

🇺🇸

Warren, Michigan, United States

Henry Ford Health Warren Hospital

🇺🇸

Warren, Michigan, United States

Henry Ford Madison Heights Hospital - Breast

🇺🇸

Warren, Michigan, United States

Henry Ford Warren Hospital - GLCMS

🇺🇸

Warren, Michigan, United States

Macomb Hematology Oncology PC

🇺🇸

Warren, Michigan, United States

Saint Mary's Oncology/Hematology Associates of West Branch

🇺🇸

West Branch, Michigan, United States

Huron Gastroenterology PC

🇺🇸

Ypsilanti, Michigan, United States

Sanford Joe Lueken Cancer Center

🇺🇸

Bemidji, Minnesota, United States

Trinity Health IHA Medical Group Hematology Oncology Ann Arbor Campus

🇺🇸

Ypsilanti, Michigan, United States

Fairview Ridges Hospital

🇺🇸

Burnsville, Minnesota, United States

Minnesota Oncology - Burnsville

🇺🇸

Burnsville, Minnesota, United States

Cambridge Medical Center

🇺🇸

Cambridge, Minnesota, United States

Mercy Hospital

🇺🇸

Coon Rapids, Minnesota, United States

Fairview Southdale Hospital

🇺🇸

Edina, Minnesota, United States

Unity Hospital

🇺🇸

Fridley, Minnesota, United States

Fairview Clinics and Surgery Center Maple Grove

🇺🇸

Maple Grove, Minnesota, United States

Minnesota Oncology Hematology PA-Maplewood

🇺🇸

Maplewood, Minnesota, United States

Saint John's Hospital - Healtheast

🇺🇸

Maplewood, Minnesota, United States

Abbott-Northwestern Hospital

🇺🇸

Minneapolis, Minnesota, United States

Hennepin County Medical Center

🇺🇸

Minneapolis, Minnesota, United States

Health Partners Inc

🇺🇸

Minneapolis, Minnesota, United States

Monticello Cancer Center

🇺🇸

Monticello, Minnesota, United States

New Ulm Medical Center

🇺🇸

New Ulm, Minnesota, United States

Fairview Northland Medical Center

🇺🇸

Princeton, Minnesota, United States

North Memorial Medical Health Center

🇺🇸

Robbinsdale, Minnesota, United States

Park Nicollet Clinic - Saint Louis Park

🇺🇸

Saint Louis Park, Minnesota, United States

Regions Hospital

🇺🇸

Saint Paul, Minnesota, United States

United Hospital

🇺🇸

Saint Paul, Minnesota, United States

Saint Francis Regional Medical Center

🇺🇸

Shakopee, Minnesota, United States

Lakeview Hospital

🇺🇸

Stillwater, Minnesota, United States

Sanford Thief River Falls Medical Center

🇺🇸

Thief River Falls, Minnesota, United States

Ridgeview Medical Center

🇺🇸

Waconia, Minnesota, United States

Rice Memorial Hospital

🇺🇸

Willmar, Minnesota, United States

Minnesota Oncology Hematology PA-Woodbury

🇺🇸

Woodbury, Minnesota, United States

Sanford Cancer Center Worthington

🇺🇸

Worthington, Minnesota, United States

Fairview Lakes Medical Center

🇺🇸

Wyoming, Minnesota, United States

Baptist Memorial Hospital and Cancer Center-Golden Triangle

🇺🇸

Columbus, Mississippi, United States

Baptist Cancer Center-Grenada

🇺🇸

Grenada, Mississippi, United States

Novant Health Cancer Institute - Statesville

🇺🇸

Statesville, North Carolina, United States

Baptist Memorial Hospital and Cancer Center-Union County

🇺🇸

New Albany, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Oxford

🇺🇸

Oxford, Mississippi, United States

Baptist Memorial Hospital and Cancer Center-Desoto

🇺🇸

Southhaven, Mississippi, United States

Saint Louis Cancer and Breast Institute-Ballwin

🇺🇸

Ballwin, Missouri, United States

Central Care Cancer Center - Bolivar

🇺🇸

Bolivar, Missouri, United States

Mercy Cancer Center - Cape Girardeau

🇺🇸

Cape Girardeau, Missouri, United States

Saint Francis Medical Center

🇺🇸

Cape Girardeau, Missouri, United States

Saint Luke's Hospital

🇺🇸

Chesterfield, Missouri, United States

Parkland Health Center - Farmington

🇺🇸

Farmington, Missouri, United States

MU Health Care Goldschmidt Cancer Center

🇺🇸

Jefferson City, Missouri, United States

Freeman Health System

🇺🇸

Joplin, Missouri, United States

Mercy Hospital Joplin

🇺🇸

Joplin, Missouri, United States

Mercy Clinic-Rolla-Cancer and Hematology

🇺🇸

Rolla, Missouri, United States

Phelps Health Delbert Day Cancer Institute

🇺🇸

Rolla, Missouri, United States

Heartland Regional Medical Center

🇺🇸

Saint Joseph, Missouri, United States

Saint Louis Cancer and Breast Institute-South City

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital South

🇺🇸

Saint Louis, Missouri, United States

Missouri Baptist Medical Center

🇺🇸

Saint Louis, Missouri, United States

Mercy Hospital Saint Louis

🇺🇸

Saint Louis, Missouri, United States

Sainte Genevieve County Memorial Hospital

🇺🇸

Sainte Genevieve, Missouri, United States

Mercy Hospital Springfield

🇺🇸

Springfield, Missouri, United States

CoxHealth South Hospital

🇺🇸

Springfield, Missouri, United States

Missouri Baptist Sullivan Hospital

🇺🇸

Sullivan, Missouri, United States

BJC Outpatient Center at Sunset Hills

🇺🇸

Sunset Hills, Missouri, United States

Mercy Hospital Washington

🇺🇸

Washington, Missouri, United States

Community Hospital of Anaconda

🇺🇸

Anaconda, Montana, United States

Billings Clinic Cancer Center

🇺🇸

Billings, Montana, United States

Bozeman Health Deaconess Hospital

🇺🇸

Bozeman, Montana, United States

Benefis Sletten Cancer Institute

🇺🇸

Great Falls, Montana, United States

Great Falls Clinic

🇺🇸

Great Falls, Montana, United States

Logan Health Medical Center

🇺🇸

Kalispell, Montana, United States

Saint Patrick Hospital - Community Hospital

🇺🇸

Missoula, Montana, United States

Community Medical Center

🇺🇸

Missoula, Montana, United States

Nebraska Cancer Specialists/Oncology Hematology West PC

🇺🇸

Grand Island, Nebraska, United States

CHI Health Good Samaritan

🇺🇸

Kearney, Nebraska, United States

Saint Elizabeth Regional Medical Center

🇺🇸

Lincoln, Nebraska, United States

Cancer Partners of Nebraska

🇺🇸

Lincoln, Nebraska, United States

Alegent Health Immanuel Medical Center

🇺🇸

Omaha, Nebraska, United States

Memorial Sloan Kettering Basking Ridge

🇺🇸

Basking Ridge, New Jersey, United States

Englewood Hospital and Medical Center

🇺🇸

Englewood, New Jersey, United States

Jersey City Medical Center

🇺🇸

Jersey City, New Jersey, United States

Alegent Health Bergan Mercy Medical Center

🇺🇸

Omaha, Nebraska, United States

Creighton University Medical Center

🇺🇸

Omaha, Nebraska, United States

Midlands Community Hospital

🇺🇸

Papillion, Nebraska, United States

Alegent Health Lakeside Hospital

🇺🇸

Omaha, Nebraska, United States

Monmouth Medical Center Southern Campus

🇺🇸

Lakewood, New Jersey, United States

Saint Barnabas Medical Center

🇺🇸

Livingston, New Jersey, United States

Monmouth Medical Center

🇺🇸

Long Branch, New Jersey, United States

Memorial Sloan Kettering Monmouth

🇺🇸

Middletown, New Jersey, United States

Memorial Sloan Kettering Bergen

🇺🇸

Montvale, New Jersey, United States

Rutgers Cancer Institute of New Jersey

🇺🇸

New Brunswick, New Jersey, United States

The Valley Hospital - Luckow Pavilion

🇺🇸

Paramus, New Jersey, United States

Neurosurgeons of New Jersey-Ridgewood

🇺🇸

Ridgewood, New Jersey, United States

Valley Health System Ridgewood Campus

🇺🇸

Ridgewood, New Jersey, United States

Robert Wood Johnson University Hospital Somerset

🇺🇸

Somerville, New Jersey, United States

Valley Health System-Hematology/Oncology

🇺🇸

Westwood, New Jersey, United States

University of New Mexico Cancer Center

🇺🇸

Albuquerque, New Mexico, United States

New Mexico Oncology Hematology Consultants

🇺🇸

Albuquerque, New Mexico, United States

Montefiore Medical Center-Einstein Campus

🇺🇸

Bronx, New York, United States

Montefiore Medical Center-Weiler Hospital

🇺🇸

Bronx, New York, United States

Montefiore Medical Center - Moses Campus

🇺🇸

Bronx, New York, United States

Roswell Park Cancer Institute

🇺🇸

Buffalo, New York, United States

Novant Health Cancer Institute - Thomasville

🇺🇸

Thomasville, North Carolina, United States

Memorial Sloan Kettering Commack

🇺🇸

Commack, New York, United States

The Cancer Institute at Saint Francis Hospital

🇺🇸

East Hills, New York, United States

Glens Falls Hospital

🇺🇸

Glens Falls, New York, United States

Memorial Sloan Kettering Westchester

🇺🇸

Harrison, New York, United States

Mount Sinai Chelsea

🇺🇸

New York, New York, United States

Mount Sinai Hospital

🇺🇸

New York, New York, United States

Memorial Sloan Kettering Cancer Center

🇺🇸

New York, New York, United States

Upstate Cancer Center at Oswego

🇺🇸

Oswego, New York, United States

State University of New York Upstate Medical University

🇺🇸

Syracuse, New York, United States

Memorial Sloan Kettering Nassau

🇺🇸

Uniondale, New York, United States

Upstate Cancer Center at Verona

🇺🇸

Verona, New York, United States

Wayne Hospital

🇺🇸

Greenville, Ohio, United States

Good Samaritan University Hospital

🇺🇸

West Islip, New York, United States

Dickstein Cancer Treatment Center

🇺🇸

White Plains, New York, United States

Novant Health Presbyterian Medical Center

🇺🇸

Charlotte, North Carolina, United States

Southeastern Medical Oncology Center-Clinton

🇺🇸

Clinton, North Carolina, United States

Southeastern Medical Oncology Center-Goldsboro

🇺🇸

Goldsboro, North Carolina, United States

Novant Health Cancer Institute - Huntersville

🇺🇸

Huntersville, North Carolina, United States

Southeastern Medical Oncology Center-Jacksonville

🇺🇸

Jacksonville, North Carolina, United States

ECU Health Oncology Kenansville

🇺🇸

Kenansville, North Carolina, United States

Novant Health Cancer Institute - Kernersville

🇺🇸

Kernersville, North Carolina, United States

ECU Health Oncology Kinston

🇺🇸

Kinston, North Carolina, United States

Novant Health Cancer Institute - Matthews

🇺🇸

Matthews, North Carolina, United States

Novant Health Cancer Institute - Mooresville

🇺🇸

Mooresville, North Carolina, United States

Novant Health Cancer Institute - Mount Airy

🇺🇸

Mount Airy, North Carolina, United States

Novant Health Cancer Institute - Wilkesboro

🇺🇸

North Wilkesboro, North Carolina, United States

ECU Health Oncology Richlands

🇺🇸

Richlands, North Carolina, United States

Novant Health Forsyth Medical Center

🇺🇸

Winston-Salem, North Carolina, United States

Sanford Bismarck Medical Center

🇺🇸

Bismarck, North Dakota, United States

Sanford South University Medical Center

🇺🇸

Fargo, North Dakota, United States

Southpointe-Sanford Medical Center Fargo

🇺🇸

Fargo, North Dakota, United States

Sanford Medical Center Fargo

🇺🇸

Fargo, North Dakota, United States

Sanford Broadway Medical Center

🇺🇸

Fargo, North Dakota, United States

Sanford Roger Maris Cancer Center

🇺🇸

Fargo, North Dakota, United States

UH Seidman Cancer Center at UH Avon Health Center

🇺🇸

Avon, Ohio, United States

UHHS-Chagrin Highlands Medical Center

🇺🇸

Beachwood, Ohio, United States

Indu and Raj Soin Medical Center

🇺🇸

Beavercreek, Ohio, United States

Strecker Cancer Center-Belpre

🇺🇸

Belpre, Ohio, United States

Saint Elizabeth Boardman Hospital

🇺🇸

Boardman, Ohio, United States

Dayton Physicians LLC-Miami Valley South

🇺🇸

Centerville, Ohio, United States

Miami Valley Hospital South

🇺🇸

Centerville, Ohio, United States

Geauga Hospital

🇺🇸

Chardon, Ohio, United States

Adena Regional Medical Center

🇺🇸

Chillicothe, Ohio, United States

University of Cincinnati Cancer Center-UC Medical Center

🇺🇸

Cincinnati, Ohio, United States

Good Samaritan Hospital - Cincinnati

🇺🇸

Cincinnati, Ohio, United States

Oncology Hematology Care Inc-Kenwood

🇺🇸

Cincinnati, Ohio, United States

Bethesda North Hospital

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Westside

🇺🇸

Cincinnati, Ohio, United States

TriHealth Cancer Institute-Anderson

🇺🇸

Cincinnati, Ohio, United States

Case Western Reserve University

🇺🇸

Cleveland, Ohio, United States

Cleveland Clinic Foundation

🇺🇸

Cleveland, Ohio, United States

Mount Carmel East Hospital

🇺🇸

Columbus, Ohio, United States

Columbus Oncology and Hematology Associates Inc

🇺🇸

Columbus, Ohio, United States

Riverside Methodist Hospital

🇺🇸

Columbus, Ohio, United States

Grant Medical Center

🇺🇸

Columbus, Ohio, United States

The Mark H Zangmeister Center

🇺🇸

Columbus, Ohio, United States

Mount Carmel Health Center West

🇺🇸

Columbus, Ohio, United States

Doctors Hospital

🇺🇸

Columbus, Ohio, United States

Miami Valley Hospital

🇺🇸

Dayton, Ohio, United States

Premier Blood and Cancer Center

🇺🇸

Dayton, Ohio, United States

Dayton Physician LLC - Englewood

🇺🇸

Dayton, Ohio, United States

Miami Valley Hospital North

🇺🇸

Dayton, Ohio, United States

Delaware Health Center-Grady Cancer Center

🇺🇸

Delaware, Ohio, United States

Grady Memorial Hospital

🇺🇸

Delaware, Ohio, United States

Dublin Methodist Hospital

🇺🇸

Dublin, Ohio, United States

Armes Family Cancer Center

🇺🇸

Findlay, Ohio, United States

Blanchard Valley Hospital

🇺🇸

Findlay, Ohio, United States

Orion Cancer Care

🇺🇸

Findlay, Ohio, United States

Dayton Physicians LLC-Wayne

🇺🇸

Greenville, Ohio, United States

Atrium Medical Center-Middletown Regional Hospital

🇺🇸

Franklin, Ohio, United States

Dayton Physicians LLC-Atrium

🇺🇸

Franklin, Ohio, United States

Central Ohio Breast and Endocrine Surgery

🇺🇸

Gahanna, Ohio, United States

Miami Valley Cancer Care and Infusion

🇺🇸

Greenville, Ohio, United States

Greater Dayton Cancer Center

🇺🇸

Kettering, Ohio, United States

Kettering Medical Center

🇺🇸

Kettering, Ohio, United States

Fairfield Medical Center

🇺🇸

Lancaster, Ohio, United States

Saint Rita's Medical Center

🇺🇸

Lima, Ohio, United States

Cleveland Clinic Cancer Center Mansfield

🇺🇸

Mansfield, Ohio, United States

OhioHealth Mansfield Hospital

🇺🇸

Mansfield, Ohio, United States

Marietta Memorial Hospital

🇺🇸

Marietta, Ohio, United States

OhioHealth Marion General Hospital

🇺🇸

Marion, Ohio, United States

Memorial Hospital

🇺🇸

Marysville, Ohio, United States

Hillcrest Hospital Cancer Center

🇺🇸

Mayfield Heights, Ohio, United States

UH Seidman Cancer Center at Lake Health Mentor Campus

🇺🇸

Mentor, Ohio, United States

UH Seidman Cancer Center at Southwest General Hospital

🇺🇸

Middleburg Heights, Ohio, United States

Knox Community Hospital

🇺🇸

Mount Vernon, Ohio, United States

Licking Memorial Hospital

🇺🇸

Newark, Ohio, United States

Newark Radiation Oncology

🇺🇸

Newark, Ohio, United States

University Hospitals Parma Medical Center

🇺🇸

Parma, Ohio, United States

Southern Ohio Medical Center

🇺🇸

Portsmouth, Ohio, United States

UH Seidman Cancer Center at Firelands Regional Medical Center

🇺🇸

Sandusky, Ohio, United States

Springfield Regional Cancer Center

🇺🇸

Springfield, Ohio, United States

Springfield Regional Medical Center

🇺🇸

Springfield, Ohio, United States

Mercy Health - Saint Vincent Hospital

🇺🇸

Toledo, Ohio, United States

Mercy Health - Saint Anne Hospital

🇺🇸

Toledo, Ohio, United States

Upper Valley Medical Center

🇺🇸

Troy, Ohio, United States

University Hospitals Sharon Health Center

🇺🇸

Wadsworth, Ohio, United States

South Pointe Hospital

🇺🇸

Warrensville Heights, Ohio, United States

Saint Joseph Warren Hospital

🇺🇸

Warren, Ohio, United States

University of Cincinnati Cancer Center-West Chester

🇺🇸

West Chester, Ohio, United States

Saint Ann's Hospital

🇺🇸

Westerville, Ohio, United States

UH Seidman Cancer Center at Saint John Medical Center

🇺🇸

Westlake, Ohio, United States

Saint Elizabeth Youngstown Hospital

🇺🇸

Youngstown, Ohio, United States

Genesis Healthcare System Cancer Care Center

🇺🇸

Zanesville, Ohio, United States

University of Oklahoma Health Sciences Center

🇺🇸

Oklahoma City, Oklahoma, United States

Integris Southwest Medical Center

🇺🇸

Oklahoma City, Oklahoma, United States

Mercy Hospital Oklahoma City

🇺🇸

Oklahoma City, Oklahoma, United States

Integris Cancer Institute of Oklahoma

🇺🇸

Oklahoma City, Oklahoma, United States

Saint Alphonsus Cancer Care Center-Baker City

🇺🇸

Baker City, Oregon, United States

Saint Charles Health System

🇺🇸

Bend, Oregon, United States

Clackamas Radiation Oncology Center

🇺🇸

Clackamas, Oregon, United States

Providence Cancer Institute Clackamas Clinic

🇺🇸

Clackamas, Oregon, United States

Bay Area Hospital

🇺🇸

Coos Bay, Oregon, United States

Providence Newberg Medical Center

🇺🇸

Newberg, Oregon, United States

Saint Alphonsus Cancer Care Center-Ontario

🇺🇸

Ontario, Oregon, United States

Providence Willamette Falls Medical Center

🇺🇸

Oregon City, Oregon, United States

Providence Portland Medical Center

🇺🇸

Portland, Oregon, United States

Providence Saint Vincent Medical Center

🇺🇸

Portland, Oregon, United States

Lehigh Valley Hospital-Cedar Crest

🇺🇸

Allentown, Pennsylvania, United States

Lehigh Valley Hospital - Muhlenberg

🇺🇸

Bethlehem, Pennsylvania, United States

Bryn Mawr Hospital

🇺🇸

Bryn Mawr, Pennsylvania, United States

Christiana Care Health System-Concord Health Center

🇺🇸

Chadds Ford, Pennsylvania, United States

Chambersburg Hospital

🇺🇸

Chambersburg, Pennsylvania, United States

WellSpan Medical Oncology and Hematology

🇺🇸

Hanover, Pennsylvania, United States

Main Line Health Center-Collegeville

🇺🇸

Collegeville, Pennsylvania, United States

Pocono Medical Center

🇺🇸

East Stroudsburg, Pennsylvania, United States

Ephrata Cancer Center

🇺🇸

Ephrata, Pennsylvania, United States

Main Line Health Center-Exton

🇺🇸

Exton, Pennsylvania, United States

Adams Cancer Center

🇺🇸

Gettysburg, Pennsylvania, United States

Lehigh Valley Hospital-Hazleton

🇺🇸

Hazleton, Pennsylvania, United States

Sechler Family Cancer Center

🇺🇸

Lebanon, Pennsylvania, United States

Riddle Memorial Hospital

🇺🇸

Media, Pennsylvania, United States

Paoli Memorial Hospital

🇺🇸

Paoli, Pennsylvania, United States

Fox Chase Cancer Center

🇺🇸

Philadelphia, Pennsylvania, United States

Guthrie Medical Group PC-Robert Packer Hospital

🇺🇸

Sayre, Pennsylvania, United States

Lankenau Medical Center

🇺🇸

Wynnewood, Pennsylvania, United States

Cancer Care Associates of York

🇺🇸

York, Pennsylvania, United States

WellSpan Health-York Cancer Center

🇺🇸

York, Pennsylvania, United States

WellSpan Health-York Hospital

🇺🇸

York, Pennsylvania, United States

Smilow Cancer Hospital Care Center - Westerly

🇺🇸

Westerly, Rhode Island, United States

Medical University of South Carolina

🇺🇸

Charleston, South Carolina, United States

Rapid City Regional Hospital

🇺🇸

Rapid City, South Dakota, United States

Sanford Cancer Center Oncology Clinic

🇺🇸

Sioux Falls, South Dakota, United States

Sanford USD Medical Center - Sioux Falls

🇺🇸

Sioux Falls, South Dakota, United States

Baptist Memorial Hospital and Cancer Center-Collierville

🇺🇸

Collierville, Tennessee, United States

Baptist Memorial Hospital and Cancer Center-Memphis

🇺🇸

Memphis, Tennessee, United States

Vanderbilt University/Ingram Cancer Center

🇺🇸

Nashville, Tennessee, United States

Houston Methodist San Jacinto Hospital

🇺🇸

Baytown, Texas, United States

Saint Joseph Regional Cancer Center

🇺🇸

Bryan, Texas, United States

Parkland Memorial Hospital

🇺🇸

Dallas, Texas, United States

Houston Methodist Hospital

🇺🇸

Houston, Texas, United States

Methodist Willowbrook Hospital

🇺🇸

Houston, Texas, United States

Houston Methodist West Hospital

🇺🇸

Houston, Texas, United States

UT Southwestern Simmons Cancer Center - RedBird

🇺🇸

Dallas, Texas, United States

UT Southwestern/Simmons Cancer Center-Fort Worth

🇺🇸

Fort Worth, Texas, United States

UT Southwestern/Simmons Cancer Center-Dallas

🇺🇸

Dallas, Texas, United States

Houston Methodist Saint John Hospital

🇺🇸

Nassau Bay, Texas, United States

UT Southwestern Clinical Center at Richardson/Plano

🇺🇸

Richardson, Texas, United States

Houston Methodist Sugar Land Hospital

🇺🇸

Sugar Land, Texas, United States

Houston Methodist The Woodlands Hospital

🇺🇸

The Woodlands, Texas, United States

University of Virginia Cancer Center

🇺🇸

Charlottesville, Virginia, United States

Providence Regional Cancer System-Aberdeen

🇺🇸

Aberdeen, Washington, United States

PeaceHealth Saint Joseph Medical Center

🇺🇸

Bellingham, Washington, United States

Highline Medical Center-Main Campus

🇺🇸

Burien, Washington, United States

Saint Elizabeth Hospital

🇺🇸

Enumclaw, Washington, United States

Providence Regional Cancer System-Centralia

🇺🇸

Centralia, Washington, United States

Swedish Cancer Institute-Edmonds

🇺🇸

Edmonds, Washington, United States

Providence Regional Cancer Partnership

🇺🇸

Everett, Washington, United States

Saint Francis Hospital

🇺🇸

Federal Way, Washington, United States

Swedish Cancer Institute-Issaquah

🇺🇸

Issaquah, Washington, United States

Kadlec Clinic Hematology and Oncology

🇺🇸

Kennewick, Washington, United States

Providence Regional Cancer System-Lacey

🇺🇸

Lacey, Washington, United States

Saint Clare Hospital

🇺🇸

Lakewood, Washington, United States

PeaceHealth Saint John Medical Center

🇺🇸

Longview, Washington, United States

Jefferson Healthcare

🇺🇸

Port Townsend, Washington, United States

Harrison HealthPartners Hematology and Oncology-Poulsbo

🇺🇸

Poulsbo, Washington, United States

Pacific Gynecology Specialists

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Ballard Campus

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-Cherry Hill

🇺🇸

Seattle, Washington, United States

Swedish Medical Center-First Hill

🇺🇸

Seattle, Washington, United States

PeaceHealth United General Medical Center

🇺🇸

Sedro-Woolley, Washington, United States

Providence Regional Cancer System-Shelton

🇺🇸

Shelton, Washington, United States

Saint Michael Cancer Center

🇺🇸

Silverdale, Washington, United States

Franciscan Research Center-Northwest Medical Plaza

🇺🇸

Tacoma, Washington, United States

PeaceHealth Southwest Medical Center

🇺🇸

Vancouver, Washington, United States

Providence Saint Mary Regional Cancer Center

🇺🇸

Walla Walla, Washington, United States

Providence Regional Cancer System-Yelm

🇺🇸

Yelm, Washington, United States

West Virginia University Charleston Division

🇺🇸

Charleston, West Virginia, United States

ThedaCare Regional Cancer Center

🇺🇸

Appleton, Wisconsin, United States

ThedaCare Cancer Care - Berlin

🇺🇸

Berlin, Wisconsin, United States

Marshfield Medical Center-EC Cancer Center

🇺🇸

Eau Claire, Wisconsin, United States

Mercyhealth Hospital and Cancer Center - Janesville

🇺🇸

Janesville, Wisconsin, United States

Gundersen Lutheran Medical Center

🇺🇸

La Crosse, Wisconsin, United States

Marshfield Medical Center-Marshfield

🇺🇸

Marshfield, Wisconsin, United States

Medical College of Wisconsin

🇺🇸

Milwaukee, Wisconsin, United States

Marshfield Medical Center - Minocqua

🇺🇸

Minocqua, Wisconsin, United States

ProHealth D N Greenwald Center

🇺🇸

Mukwonago, Wisconsin, United States

ThedaCare Regional Medical Center - Neenah

🇺🇸

Neenah, Wisconsin, United States

ThedaCare Cancer Care - New London

🇺🇸

New London, Wisconsin, United States

Cancer Center of Western Wisconsin

🇺🇸

New Richmond, Wisconsin, United States

ProHealth Oconomowoc Memorial Hospital

🇺🇸

Oconomowoc, Wisconsin, United States

ThedaCare Cancer Care - Oshkosh

🇺🇸

Oshkosh, Wisconsin, United States

Marshfield Medical Center-Rice Lake

🇺🇸

Rice Lake, Wisconsin, United States

ThedaCare Cancer Care - Shawano

🇺🇸

Shawano, Wisconsin, United States

Marshfield Medical Center-River Region at Stevens Point

🇺🇸

Stevens Point, Wisconsin, United States

ProHealth Waukesha Memorial Hospital

🇺🇸

Waukesha, Wisconsin, United States

UW Cancer Center at ProHealth Care

🇺🇸

Waukesha, Wisconsin, United States

ThedaCare Cancer Care - Waupaca

🇺🇸

Waupaca, Wisconsin, United States

Marshfield Medical Center - Weston

🇺🇸

Weston, Wisconsin, United States

Cheyenne Regional Medical Center-West

🇺🇸

Cheyenne, Wyoming, United States

Billings Clinic-Cody

🇺🇸

Cody, Wyoming, United States

Welch Cancer Center

🇺🇸

Sheridan, Wyoming, United States

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