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临床试验/NCT04771949
NCT04771949Unknown不适用

Prevalence and Environmental Risk Indicators for Periodontitis. A Cross-sectional Study

University of Siena1 个研究点 分布在 1 个国家目标入组 230 人开始时间: 2021年2月20日最近更新:
适应症

试验速览

阶段
不适用
入组人数
230
试验地点
1
主要终点
Prevalence of periodontitis

研究概览

简要总结

Periodontitis is a biofilm-mediated chronic inflammatory disease with a multi-factorial etiology; it belongs to the group of diseases classified as "Non-communicable Diseases" (NCDs). According to the results of the Global Burden of Disease Study of 2017, it is the sixth most prevalent disease worldwide and it constitutes a heavy burden on health costs.

Risk factors for such disease include non-modifiable risk factors, i.e. familiarity, diabetes, cardiovascular diseases, metabolic syndrome, as well as modifiable risk factors, i.e. diet, stress and low physical exercise. Given the significant impact of oral health on the quality of life and overall well being of the individual, many studies investigated the importance of risk factors for oral health. In particular, there is some evidence that more severe manifestations of periodontitis are associated with lower physical activity (De Oliveira Ferreira et al., 2019), poor sleep quality (Karaaslan & Dikilitaş, 2019) and more perceived stress (Coelho et al., 2020). With regards to diet, despite the high number of studies demonstrating an anti-inflammatory effect of the Mediterranean Diet, no study has ever investigated the adherence to Mediterranean Dieta to the oral health status.

From a methodological standpoint, investigations regarding environmental factors are mainly carried out through questionnaires administration, whose validity and reproducibility had been previously demonstrated. The novelty introduced by the present study would be a complete analysis of the effects of lifestyles (diet, sleep quality, physical exercise, perceived stress) on the periodontal status of the individual.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • age between 18 and 70 years old;
  • ability and willingness to give informed consent.

排除标准

  • pregnancy or lactation;
  • inability to communicate either in English or Italian;
  • inability or unwillingness to give informed consent.

结局指标

主要结局

Prevalence of periodontitis

时间窗: Baseline

The prevalence of periodontitis among a sample of patients coming to the dental University clinic will be calculated

次要结局

  • Adherence to mediterranean diet(Baseline)
  • Physical Activity(Baseline)
  • Sleep Quality(Baseline)
  • Italian Perceived Stress Scale (IPSS)(Baseline)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Nicola Discepoli

Researcher

University of Siena

研究点 (1)

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