MedPath

Homeopathic medicines for knee pai

Phase 2
Conditions
Health Condition 1: M179- Osteoarthritis of knee, unspecified
Registration Number
CTRI/2024/04/065097
Lead Sponsor
D. N. De Homoeopathic Medical College and Hospital
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Open to Recruitment
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1.Age 50-70 years

2.Participants of either sex or transgender.

3.Diagnosed knee OA (ICD 11- FA01) as per American College of Rheumatology (ACR) clinical/radiographic classification criteria

a. Knee pain

b. At least 1 of 3: age more than 50 yrs., stiffness less than 30 min, and crepitus on knee motion.

c. Osteophytes on knee x-ray

4. Patients already undergoing regular oral or topical analgesics or NSAID therapy for painful episodes of OA, provided the medications are stopped completely at least 2 weeks prior study entry.

5. At least 5 polar symptoms and 10 indicated remedies under a rubric.

6. Participants having prior experience or knowledge of the treatment. e.g.- primed to expect ‘homoeopathic aggravation’ and available treatment options for the disease conditions, intimated through Patient Information Sheet.

Exclusion Criteria

1.Not providing with written informed consent of participation.

2.Severe degeneration of knee joint with marked joint narrowing, varus, or valgus deformity of knee (more than 12°), evidenced by imaging or other evidences and requiring surgical intervention.

3.Non-ambulant patients.

4.Self-reported joint disorders other than osteoarthritis (e.g., inflammatory joint disease, specific arthropathy, hyperuricaemia and/or gout, severe axis deviations or instabilities, joint or skin infections, joint prostheses of the lower limbs)

5.Intra-articular injections within 2 weeks before study entry.

6.Transplanted knees.

7.Recent significant knee surgery within last 6 months.

8.Benign tumours and malignant tumours.

9.Patient suffering from active or chronic, systemic or local infection or disease.

10.Patients who are too sick for consultation.

11.Unwilling to take part and not giving consent to join the study

12.Diagnosed cases of unstable mental or psychiatric illness or other uncontrolled or life-threatening illness affecting quality of life.

13.Pregnancy, puerperal women and lactating mother.

14.Tobacco chewing and/or smoking, alcoholism and/or any form(s) of substance abuse and/or dependence (TAPS tool).

15.Self-reported immune-compromised state, AIDS, hepatitis etc.

16.Undergoing homoeopathic treatment for any chronic disease within last 6 months.

17.Simultaneous participation in any other clinical trial.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Modified Pain Detection (mPDQ) questionnaireTimepoint: Every month up to 3 months
Secondary Outcome Measures
NameTimeMethod
Knee Injury and Osteoarthritis Outcome Score (KOOS) <br/ ><br>Timepoint: Every month up to 3 months;Measure Yourself Medical Outcome Profile (MYMOP-2) <br/ ><br>Timepoint: Every month up to 3 months;Time to resolution of pain of kneeTimepoint: Every week up to 3 months
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