Pharmacist-led Intervention to Reduce Potentially Inappropriate Prescription in Elderly and Polypharmacy Patients at Primary Care Setting (PHARM-PC) Cluster Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 549
- 试验地点
- 2
- 主要终点
- Number of patients with potentially inappropriate prescriptions (PIP)
研究概览
简要总结
PHARM-PC study is based on identify potentially inappropriate prescriptions (PIP) and delivery therapeutic appropriateness recommendations from the pharmacist to the physician and about drugs prescribed for elderly and polypharmacy patients in primary care. Assessment of the impact of pharmacist intervention on the appropriateness of prescribing and both health outcomes and economic outcomes will be done.
详细描述
Main objective:
To assess the effect of Pharmaceutical Intervention (PI) on PIP in elderly patients with polypharmacy in PC.
Secondary objectives:
2. a. Assess baseline characteristics of elderly polypharmacy patients in PC; and assess association with the possible presence of PIP.
2. b. Describe the main types and the reasons for PIP. 3. Assess impact of PI on health outcomes (morbidity and mortality). 4. Estimate the effect of IF on the cost of both drugs and healthcare resources.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age ≥ 65 years
- •treatment with 5 or more chronic medications.
排除标准
- •routine monitoring is carried out in private health care
- •temporary displaced persons (routine monitoring is carried out in another community).
- •Institutionalized patients
- •Patients in the Home Care Program
结局指标
主要结局
Number of patients with potentially inappropriate prescriptions (PIP)
时间窗: Up to 6 months
This variable will be measured six months after intervention, when a new review of patient treatment will be performed to check acceptance by the physician of the recommendations issued by the pharmacist. PIP: Prescription (drug, dose, frequency of administration) that meets at least one of the following conditions: contraindication, inadequate dosing (dose, frequency and / or duration), duplication, interactions, probability of adverse drug reactions, health problem insufficiently treated, unnecessary medication; new drugs of little-no therapeutic value, drug which is not considered as first choice in the treatment of the most prevalent diseases in the outpatient setting.
Mean number of PIP per patient
时间窗: Up to 6 months
This variable will be measured six months after intervention, when a new review of patient treatment will be performed to check acceptance by the physician of the recommendations issued by the pharmacist.
次要结局
- Morbidity(Up to 12 months)
- Total spending on drugs(Up to 6 months)
- Total spending on health resources.(Up to 12 months)
- Mortality(Up to 12 months)
研究者
Jesus Martinez Sotelo
Pharm D
Hospital Comarcal de Inca