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临床试验/CTRI/2025/03/082429
CTRI/2025/03/082429尚未招募不适用

RANDOMIZED CONTROLLED CLINICAL STUDY TO EVALUATE THE EFFICACY OF KADALI PRATISARNIYA KHAR IN THE MANAGEMENT OF KADAR W.S.R. TO CORN

Dr VJD Gramin Ayurved Mahavidyalaya1 个研究点 分布在 1 个国家目标入组 60 人开始时间: 2025年3月27日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
60
试验地点
1
主要终点
2)Tenderness

研究概览

简要总结

Placing the feet on hard/ rough stone/surface or wound caused by thorns etc. or by doshas getting aggravated together along with Meda and Rakta dhatu, gives rise to a tumour-like hard induration deep seated in the middle and elevated at the periphery, having the size of a Kola and presenting the symptoms of pain and exudation, sometimes discharge is known as Kadara.                                                                                                                                                                                 Kadara has been described in the classical literature, like Sushruta Samhita under the heading Kshudra Roga. It is a condition formed by vitiation of Vata and Kapha Dosha which in turn vitiates Rakta and Meda dhatus.

Sushruta has mentioned four types of treatments, i.e., bheshaja (medicines), ksharakarma (Application of alkali preparation), agnikarma (Cauterization) and Shastrakarma (Surgery) as chikitsopakarma for Asha (piles) in Sushruta samhitha sutra sthana and he has given more emphasis on ksharakarma which also holds good for treatment o fCharmakeela and Kadara.

Kadara is referred to be effectively treated with Kshara Karma as Teekshna Ksharalepa performs actions like Chedana, Bedhana, Lekhana. Teekshna Kshara pacifies the Vata and Kapha Doshas and dissolves Meda Dhatu which is needed for the Samprapti Vighatana ofKadara.

Corn can be correlated with kadara described in Ayurveda Samhitas.                                                                                                                                                                                            A corn is known as hyperkeratosis ofskin. It usually occurs at the pressure sites 1.e. sole and toes. It presents as a whitish, circular area that can be extremely painful when palpated. Corns can also appear on the sides or the tips of the paw pad (these being not much common). It can sometimes appear between the toes is softer in consistency and less painful.

The reason for the pain is that corns contain a cone-shaped core/root whose

point can press on a nerve, causing severe pain and lameness as fi one is walking with a sharp pebble in the shoe.

The management of corn consists of destruction of abnormal tissue by

application of salicylic acid, invasive procedures like cryotherapy, laser, electric

and chemical cauterization and complete excision by surgery. These procedures are relatively expensive and have bothersome post wound care.

Corn is a horny induration of the cuticle with a hard cent

研究设计

研究类型
Interventional
分配方式
Coin toss, Lottery, toss of dice, shuffling cards etc
盲法
None

入排标准

年龄范围
25.00 Year(s) 至 50.00 Year(s)(—)
性别
All

入选标准

  • .1 Patients with signs and symptoms ofKadar (Corn) will be selected.
  • Age: between
  • 50 years irrespective of sex
  • Patients will be selected who are willing to give informed consent and ready to comply with the protocol.

排除标准

  • 1.Patient with Pittaj prakruti 2.Patients with Uncontrolled Systemic disorders like Diabetes, Hypertension.
  • 3.Patients with infective conditions like HIV and Hbs Ag were excluded.
  • 4.Pregnant women.
  • 5.Patient on anti-platelet drug.

结局指标

主要结局

2)Tenderness

时间窗: Follow up | 0,3rd,5th,7th,9th,11th,13th,15th days

1)Pain

时间窗: Follow up | 0,3rd,5th,7th,9th,11th,13th,15th days

3)Consistency

时间窗: Follow up | 0,3rd,5th,7th,9th,11th,13th,15th days

Will be decreased of kadar with reference to corn

时间窗: Follow up | 0,3rd,5th,7th,9th,11th,13th,15th days

次要结局

  • Decrease in symptoms of Kadar(18 months)

研究者

发起方
Dr VJD Gramin Ayurved Mahavidyalaya
申办方类型
Research institution and hospital
责任方
Principal Investigator
主要研究者

Dr Hrushikesh Suresh Bhakare

Dr VJD Gramin Ayurved Mahavidyalaya Near Renuka mata mandir patur

研究点 (1)

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