Efficacy of Phlai capsule and loratadine as treatment in allergic rhinitis patients
- Conditions
- Peak nasal inspiration flowEfficacy of Phlai capsule in allergic rhinitis patientTotal nasal symptom scoresOcular scoresVisual analogue scale
- Registration Number
- TCTR20171111002
- Lead Sponsor
- Thai Traditional Medical Knowledge Fund
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 75
1.age between 18-50 years old
2. Diagnose of allergic rhinitis (at least mild intermittent)
3. Daily Total nasal symptoms score 6-10 on 3 consecutive day
4. Skin test positive at least one from five aeroallergen (house dust mite, cockroach, cat hair, dog dander, Bermuda grass)
5. Do not use
- Intradermal nasal steroid 2 week
- Systemic corticosteroid 2 week
- Antihistamine 1 week
- Intranasal or systemic decongestant 3 day
6. No smoking
7. No alcohol use
8. No allergic history to herb
1. Have chronic illness or underlying disease (heart is ease, renal disease ,liver disease)
2. During on immunotherapy for allergic rhinitis treatment
3.Asthmatic patient
4.Take antidepressant, sedative ,anxiolytics, opioids, neuroleptic drug
5. After intranasal surgery within 6 months
6. Nasal polyp, nasal septum deviation, acute or chronic rhinosinusitis
7. Pregnancy or lactation
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Total nasal symptom score 8 wk Sum of score
- Secondary Outcome Measures
Name Time Method Quality of life 8 wk Sum of score,Peak nasal inspiration flow 8 wk Mean score,Visual analogue scale score 8 wk Mean