Applying Artificial Intelligence to Identify Subphenotypes of Acute Kidney Injury in Mexican Patients With Severe COVID-19

Completed

• Conditions: Acute Kidney Injury; COVID-19

• Registration Number: NCT06471101
• Lead Sponsor: Instituto Nacional de Enfermedades Respiratorias

Brief Summary

The goal of this observational study was to identify subphenotypes of acute kidney injury patients with COVID-19, and the investigators analyzed their impact on mortality. The study included demographic and clinical variables of the participants. The implementation of Machine Learning algorithms and Artificial Intelligence methods are used, and some specific implementations were designed for the analysis, where each group was characterized by traditional statistical methods.

Detailed Description

Not available

Study Timeline

• Status Verified: 2024-06
• Study Start: 2024-06-18
• Primary Completion: 2024-06-18
• Study Completion: 2024-06-18
• Study First Submitted: 2024-06-18
• Study First Submitted QC: 2024-06-20
• Last Update Submitted: 2024-06-20
• Study First Posted: 2024-06-24
• Last Update Posted: 2024-06-24

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 2934

Inclusion Criteria

• Patients older than 15 years old, hospitalized, and with severe acute respiratory syndrome (SARS-CoV-2) positive confirmation.

Exclusion Criteria

• Patients who did not have at least 1 creatinine measurement.

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Subphenotypes of acute kidney injury in patients	Through study completion, an average of one month	Number of acute kidney injury subphenotypes in patients with COVID-19

Secondary Outcome Measures

Name	Time	Method
Length of stay of acute kidney injury patients	Through study completion, an average of one month	Differences in-hospital length of stay in acute kidney injury subphenotypes of patients with COVID-19.
Mortality of acute kidney injury patients	Through study completion, an average of one month	Differences between mortality rates in acute kidney injury subphenotypes of patients with COVID-19
Severity of acute kidney injury patients	Through study completion, an average of one month	Differences between severity stages in acute kidney injury subphenotypes of patients with COVID-19
Renal replacement therapy requirement in acute kidney injury patients	Through study completion, an average of one month	Differences between renal replacement therapy requirement rates in acute kidney injury subphenotypes of patients with COVID-19
Non-recovery in acute kidney injury patients	Through study completion, an average of one month	Differences between non recovery rates in acute kidney injury subphenotypes of patients with COVID-19

Trial Locations

Locations (1)

Instituto Nacional de Enfermedades Respiratorias; 🇲🇽 Mexico City, Mexico