Long-term Benefit of Aortic Stent-graft in Patients With Distal Aortic Dissection
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 入组人数
- 7
- 试验地点
- 2
- 主要终点
- Aortic aneurysm and death
研究概览
简要总结
Background: Aortic stent-graft is useful to occlude intimal tear and prevent further dilatation of the false lumen in patients with aortic dissection. The long-term benefit of aortic stent-graft in patients with uncomplicated distal aortic dissection has not been well demonstrated, especially in patients at high risk of aneurysmal change and death.
Purpose: The purpose of the study is to evaluate long-term clinical benefit of stent-graft insertion performed just after the acute phase into the descending thoracic aorta in patients with distal aortic dissection and at high risk of aneurysmal change of the dissected aorta.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- — 至 75 Years(Child, Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Uncomplicated distal aortic dissection
- •Initial false lumen diameter >= 22 mm
排除标准
- •Old age (> 75 years old)
- •Other comorbidity or malignancy with life expectancy < 5 years
- •Complicated dissection requiring aortic surgery or intervention
- •Sudden death in acute phase
- •Marfan syndrome
结局指标
主要结局
Aortic aneurysm and death
时间窗: 4 years
次要结局
- Events and complications(4 years)
研究者
Jong-Min Song
Associate professor
Asan Medical Center
