Dresden Glaucoma and Treatment Study (DGTS)

Recruiting

• Conditions: Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Glaucoma, Low Tension; Glaucoma

• Registration Number: NCT02959242
• Lead Sponsor: Technische Universität Dresden

Brief Summary

To assure the quality of follow-up and treatment, data of glaucoma patients are stored and evaluated after anonymisation.

Detailed Description

The aim of the study is to evaluate the quality of follow-up and treatment by means of consecutive data collection and anonymised analysis of all glaucoma patients of a tertiary university hospital glaucoma service.

Parameters being analyzed are:

Age, sex, refraction, family history, known duration of glaucoma, highest intraocular pressure before treatment, systemic and topical medication, previous ocular surgery.

24h Goldmann-applanation tonometry, biomicroscopy, gonioscopy, Heidelberg Retinal Tomograph (HRT), glaucoma diagnosis with Scanning-Laser-Polarimetry (GDx), optical coherence tomography (OCT), Pentacam, Ocular Response Analyzer (ORA), Corvis ST (Corneal Visualization with the Scheimpflug Technology), perimetry

Study Timeline

• Study Start: 2006-01
• Study First Submitted: 2016-11-07
• Study First Submitted QC: 2016-11-08
• Study First Posted: 2016-11-09
• Status Verified: 2025-02
• Last Update Submitted: 2025-02-03
• Last Update Posted: 2025-02-04
• Primary Completion: 2030-12
• Study Completion: 2030-12

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

• manifest glaucoma, ocular Hypertension, glaucoma suspect

Exclusion Criteria

• under 18 years of age, corneal diseases

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Follow-up intervals	20 years	To find the best follow-up intervals for glaucoma patients.

Secondary Outcome Measures

Name	Time	Method
Assessment of treatment quality	20 years	What is the best treatment option for the individual patient?
Assessment of intraocular pressure-lowering efficacy and number of participants with treatment-related adverse events as assessed by CTCAE v4.0 of glaucoma laser therapy	20 years	Diurnal intraocular pressure, best corrected visual acuity, visual fields
Assessment of intraocular pressure-lowering efficacy and number of participants with treatment-related adverse events as assessed by CTCAE v4.0 of glaucoma laser therapy of glaucoma surgery	20 years	Diurnal intraocular pressure, best corrected visual acuity, visual fields

Trial Locations

Locations (1)

University Eye Hospital, Medical Faculty, Technical University Dresden; 🇩🇪 Dresden, Saxony, Germany