Identification of risk factors for oral precancer and cancerous lesions.
Not Applicable
- Conditions
- Health Condition 1: C00-C14- Malignant neoplasms of lip, oral cavity and pharynx
- Registration Number
- CTRI/2020/11/028878
- Lead Sponsor
- Center for Cancer Epidemiology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
oral precancer and oral cancer lesions
Exclusion Criteria
History of cancer.
Prior history of precancer/cancer directed treatment
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Conduct a whole exome sequencing to characterize the landscape of somatic mutations in oral pre-cancers and cancers.Timepoint: 2 Years
- Secondary Outcome Measures
Name Time Method 1)Conduct a whole genome sequencing on tumour-blood pair to identify mutation signature attributed to exposures. <br/ ><br>2)Conduct a whole genome sequencing on oral pre-cancer -blood pair to identify mutation signature attributed to exposures. <br/ ><br>3)To investigate the feasibility and validity of the measurement of driver somatic mutations in less-invasively collected samples, such as oral cytology samples, saliva, and oral rinses. <br/ ><br> <br/ ><br>Timepoint: 2 years