NCT00044434已完成4 期
Bupropion as a Smoking Cessation Aid in Alcoholics
National Institute on Alcohol Abuse and Alcoholism (NIAAA)2 个研究点 分布在 1 个国家目标入组 200 人开始时间: 2002年5月1日最近更新:
适应症
相关药物
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 发起方
- 入组人数
- 200
- 试验地点
- 2
研究概览
简要总结
The purpose of this study is to test the use of time-released bupropion (Wellbutrin) in patients receiving treatment for alcohol abuse/dependence as an aid to stop smoking. Patients will receive either a time-released bupropion or placebo. Both groups will receive nicotine replacement therapy during the 9 week study. A final followup assessment will be conducted 6 months from the start of treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 主要目的
- Treatment
- 盲法
- Double
入排标准
- 年龄范围
- 25 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Currently a patient in the Omaha VA Medical Center, Substance Abuse Treatment Center (SATC) or at Catholic Charities Campus for Hope.
- •Have a diagnosis of alcohol abuse or alcohol dependence.
- •Smoke 20 or more cigarettes/day (may also smoke pipes/cigars).
- •Be interested in quitting smoking.
- •Provide name, addresses, and phone numbers of at least two individuals who can provide information on their alcohol, nicotine, and other drug use during the follow-up period.
- •If female, patient must a) be of non-childbearing potential, b) have a negative pregnancy test, c) sign a document stating they do not plan on becoming pregnant during the study.
- •Agree to sign informed consent.
- •Able to read and understand study-related forms and procedures.
排除标准
- •Advanced cardiac, pulmonary, renal, or liver disease.
- •History of seizures.
- •History of brain tumor or significant head trauma.
- •History of bulimia or anorexia nervosa.
- •Current major depressive disorder or past history of panic disorders, schizophrenia, or bipolar affective disorder.
- •Using psychoactive drugs.
- •Receiving treatment with medications that lower seizure thresholds.
- •Use of an investigational drug in any study in the past four weeks.
- •Currently using any asthma medication.
- •Used time-released bupropion in the past 12 months.
- •Currently using any other treatments to stop smoking.
研究者
研究点 (2)
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