Can the presence of insecticide treated materials in the household control dengue vectors?
Not Applicable
Completed
- Conditions
- Dengue (including Dengue Haemorrhagic Fever [DHF] and Dengue Shock Syndrome [DSS])Infections and InfestationsDengue fever [classical dengue]
- Registration Number
- ISRCTN52339690
- Lead Sponsor
- iverpool School of Tropical Medicine (UK)
- Brief Summary
2006 results in https://pubmed.ncbi.nlm.nih.gov/16735334 (added 19/02/2020)
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 1122
Inclusion Criteria
All occupied households
Exclusion Criteria
1. Business-only premises
2. Multi-storey buildings
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <br> Entomological outcomes, the standard larval indices for the Aedes aegypti mosquito vector of dengue:<br> 1. Breteau index: number of containers with immature stages per 100 houses<br> 2. House index: number of houses containing immature stages per 100 houses<br> 3. Container index: number of containers with immature stages per 100 containers with water<br> 4. Pupal surveys were also undertaken to calculate the number of pupae per person index (number of pupae collected/human population in a sector)<br><br> Follow up surveys made to all houses at 1, 18, 24, 26 months post-intervention. Analyses to measure impact of the intervention on dengue vector populations will be undertaken according to intention to treat and per protocol (based on extent of coverage as determined in follow-up surveys).<br>
- Secondary Outcome Measures
Name Time Method <br> 1. Seroconversion rates (as measured by IgM ELISA) in households in the treated and control sectors compared at baseline and at the trial's end. Members of each household between 2 - 8 years of age specifically selected for the study.<br> 2. Interview surveys used to determine:<br> 2.1. Household characteristics<br> 2.2. Previous vector control intervention<br> 2.3. Better understanding of the local population's knowledge, attitudes and practice about previous methods of dengue prevention and control, and about ITMs for the same purpose<br> 3. Insecticide-susceptibility assays undertaken before, at follow-up surveys and after intervention<br><br> Each house was also georeferenced with a handheld global positioning system receiver to permit subsequent overspill effects between adjacent treated and control clusters to be quantified.<br>