The Interaction of Flavor With Nicotine Form in Adult Smokers
试验速览
- 阶段
- 1 期
- 状态
- 已完成
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Changes in Liking of E-cigarette Overall
研究概览
简要总结
This study seeks to elucidate the impact of e-cigarette flavor on subjective effects and nicotine exposure from e-cigarettes containing different forms of nicotine.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Crossover
- 主要目的
- Other
- 盲法
- Double (Participant, Care Provider)
入排标准
- 年龄范围
- 21 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •At least 21 years old, able to read and write, use of combustible
排除标准
- 未提供
研究组 & 干预措施
E-cigarette flavor
In this arm, participants will receive two experimental e-cigarette flavors
干预措施: Nicotine form (Drug)
E-cigarette flavor
In this arm, participants will receive two experimental e-cigarette flavors
干预措施: E-cigarette experimental flavor (Other)
E-cigarette nicotine form
In this arm, participants will receive two forms of nicotine in an e-cigarette
干预措施: Nicotine form (Drug)
E-cigarette nicotine form
In this arm, participants will receive two forms of nicotine in an e-cigarette
干预措施: E-cigarette experimental flavor (Other)
结局指标
主要结局
Changes in Liking of E-cigarette Overall
时间窗: up to 3 weeks
Following each puff, each participant was assessed to determine if they liked/disliked the overall e-cigarette experience using the Labeled Hedonic Scale (LHS), a bipolar category-ratio scale with 5 symmetrical semantic labels positioned on the scale per their semantic magnitude that ranges from -100 (Most Disliked) to 100 (Most Liked) with "Neither Liked nor Disliked" at the midpoint.
Changes in Liking of E-cigarette Flavor
时间窗: up to 3 weeks
Following each puff, each participant was assessed to determine if they liked/disliked the flavors in the e-cigarette experience using the Labeled Hedonic Scale (LHS), a bipolar category-ratio scale with 5 symmetrical semantic labels positioned on the scale per their semantic magnitude that ranges from -100 (Most Disliked) to 100 (Most Liked) with "Neither Liked nor Disliked" at the midpoint.
次要结局
- gLMS: Irritation(up to 3 weeks)
- Number of Puffs(up to 3 weeks)
- gLMS: Sweetness(up to 3 weeks)
- gLMS: Coolness(up to 3 weeks)