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Eliquis Regulatory Post Marketing Surveillance

Completed
Conditions
NonValvular Atrial Fibrillation
Interventions
Registration Number
NCT01885598
Lead Sponsor
Bristol-Myers Squibb
Brief Summary

The primary objective of this study is to examine the safety profile of Eliquis in Korean nonvalvular atrial fibrillation patients.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
3335
Inclusion Criteria
  • Patients ≥19 years of age
  • Adult patients who are diagnosed with nonvalvular atrial fibrillation and are initiating Eliquis anticoagulation therapy for risk reduction of stroke and systemic embolism
  • Patients with evidence of a personally signed and dated informed consent document indicating that the patient (or a legally acceptable representative) has been informed of all pertinent aspects of the study
Exclusion Criteria
  • Receiving Eliquis treatment for an indication that is not approved in Korea
  • Contraindicated for the use of Eliquis as described in the Korean label

Study & Design

Study Type
OBSERVATIONAL
Study Design
Not specified
Arm && Interventions
GroupInterventionDescription
Nonvalvular Atrial Fibrillation patients with risk of StrokeApixabanPatients undergoing elective total hip replacement arthroplasty or elective total knee replacement arthroplasty and signed on the data release
Primary Outcome Measures
NameTimeMethod
Adverse events (AE) occurrence based on Incidence of serious adverse events, unexpected adverse drug reactions, Identification of AE profile in usual practice Nonserious adverse events, major bleedingwithin 30 days after end of the treatment
Secondary Outcome Measures
NameTimeMethod
Final identification of major events and no event based on Incidence of stroke, systemic embolism, death, Effectiveness or death at 24 months after discontinuation of therapy or at the end of the observation period (whatever is later)At 3, 6, 12, and 24 months after enrollment

Final identification of major events based on Incidence of stroke, systemic embolism, death, Effectiveness: No evidence of stroke, systemic embolism, or death at 24 months after discontinuation of therapy or at the end of the observation period (whatever is later)

Final evaluation of clinical significance of Eliquis is provided by the physician's subjective decision (Excellent, Good, Moderate, Insufficient)At 3, 6, 12, and 24 months after enrollment

Trial Locations

Locations (1)

Local Institution

🇰🇷

Seoul, Korea, Republic of

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