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临床试验/NCT01690793
NCT01690793已完成不适用

Measurement of Natriuretic Hormone Peptides in Exacerbation of Asthma

University of South Florida1 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2009年2月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
30
试验地点
1
主要终点
The measurement of NHPs after treatment of an exacerbation of asthma

研究概览

简要总结

The investigators hypothesize that there is a statistically significant decrease of Natriuretic Hormone Peptides (NHPs) in subjects with asthma exacerbation compared to levels following treatment of an exacerbation of asthma.

详细描述

Overall Study Design

  1. Measurement of Natriuretic Hormone Peptides in individuals suffering from exacerbation of asthma.
  2. Measurement of Natriuretic Hormone Peptides 5-7 days after initiation of treatment of exacerbation of asthma.
  3. Measurement of Natriuretic Hormone Peptides 10-14 days after initiation of treatment of exacerbation of asthma.

3 comparisons of Natriuretic Hormone Peptides levels will be made:

  1. Exacerbation compared to 5-7 days after initiation of treatment
  2. Exacerbation compared to 10-14 days after initiation of treatment
  3. 5-7 days after initiation of treatment compared to 10-14 days after initiation of treatment.

Samples of blood will be secured in the Division of Allergy/Immunology at the University of South Florida, Joy McCann Culverhouse Airways Disease Center. All samples will be appropriately coded to maintain confidentiality. Blood specimens will be held at minus 20 degrees Celsius.

研究设计

研究类型
Observational

入排标准

年龄范围
18 Years 至 85 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Both genders, age 18-
  • Females who are pregnant or lactating are not eligible.
  • Read and comprehend English.
  • Ability to give informed consent.
  • Seen in the outpatient setting at one of the clinic.
  • The subject must have a history of physician diagnosed asthma for at least 1 year and must have an exacerbation of asthma for entry into the study.

排除标准

  • 未提供

结局指标

主要结局

The measurement of NHPs after treatment of an exacerbation of asthma

时间窗: 14 days

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Richard Lockey

prinicpal investigator

University of South Florida

研究点 (1)

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